Amgen Bone Drug Shows Promise

[tousled1]

Patients taking hormone blockers to fight breast cancer showed improvements in bone density when given shots of an experimental Amgen Inc. bone drug, researchers said

To read full article:
http://online.wsj.com/article/SB119768630938831075.html?mod=googlenews_wsj

[suzan w]

wonder what the drug is?

[alw]

Denosumab

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<!-- start content -->Denosumab (formerly known as AMG 162) is a human (http://en.wikipedia.org/wiki/Human) monoclonal antibody (http://en.wikipedia.org/wiki/Monoclonal_antibody) which is used to treat osteoporosis (http://en.wikipedia.org/wiki/Osteoporosis). Denosumab is designed to target RANK Ligand, a protein that acts as the primary signal to promote bone removal. In many bone loss conditions, RANK Ligand overwhelms the body's natural defense against bone destruction.