Meta Analysis of Ki-67

[Hopeful]

http://www.breastcancersource.com/breastcancersourcehcp/6096_27059___.aspx

Hopeful

[Jean]

Hopful,

Very interesting article, when I saw Dr. Slamon last April we discussed Ki-67 levels and he told then that this was a very important aspect of the tumor
and that the level and the fact of having a postive Ki-67 was extremely important and that my dr. in New York had missed the boat in not addressing
this aspect of my tumor.

Interesting, thanks for posting this article.

Jean

[R.B.]

Less omega six + more omega three = less Ki-67



RB


http://www.leaonline.com/doi/abs/10.1207/S1532791444-49?cookieSet=1&journalCode=nc

Tumor prostaglandin E2 concentrations were reduced by feeding the lower LA level; further dose-dependent decreases occurred in the DHA dietary groups and were accompanied by reduced levels of 12- and 15-hydroxyeicosatetraenoic acids. These changes in eicosanoid biosynthesis may have been responsible for the observed decreases in cell proliferation, indicated by suppressed Ki-67 expression, and increases in apoptotic activity, as reflected in TdT-mediated dUTP nick end labeling immunohistochemical staining.