High potential discovery on gene therapy for metastatic liver tumors using adenovirus

[heblaj01]

This early research shows that gene therapy for liver cancer is not only showing signs of effectiveness in humans but is also safe for normal cells, an important point following the death of a patient in an past unrelated clinical trial using gene therapy.
http://health.ucsd.edu/news/2007/2_13_Reid.htm

Study Shows Liver an Excellent Target For Cancer Gene Therapy Using Viral Vectors

[jhandley]

Hi
I have been following this adenoviral theme as it has developed. This is great news..let's keep our eye out for the patient trials.
Jackie

[heblaj01]

Although not specific to liver cancer cells (as in the previous post) this modified type 2 herpes simplex virus,HSV-2, called FusOn-H2 is effective against in vivo primary & metastatic breast tumors by selectively replicating in cancer cells (& thus killing them) as well as activating the immune system

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17266169&query_hl
Induction of strong antitumor immunity by an HSV-2-based oncolytic virus in a murine mammary tumor model.