Paul C.
08-11-2003, 04:39 AM
The p53 tumor suppressor gene is frequently mutated in breast cancer. The immunohistochemical(IHC)detection of p53 characterizes patients with metastatic breast cancer unlikely to respond to paclitaxel (Taxol).
[Source: J Cancer Res Clin Oncol. 2003 May;129(5):295-302.]
[Source: J Cancer Res Clin Oncol. 2003 May;129(5):295-302.]