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Old 02-08-2010, 05:44 PM   #1
Angela
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Join Date: Apr 2006
Location: North Carolina
Posts: 45
Thumbs down Gemzar

My tumors are growing and spreading. I will be taking Gemzar starting next week. Has anyone been on this chemo drug before? If so, what kind of side effects did you experience? Any information you can provide would be most helpful.

Thanks!
Hugs and Smiles
Angela
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Hugs and Smiles,
Angela - NC

Dx May 2003 at age 39
Lt mastectomy, no nodes
DCIS, PR- ER- Her+++
4 rounds AC
Recurrence Dec 2006 Rt lung
2/07 - 3 Brain mets - Radiation
3/07 -
Carboplatin and Herceptin
8/07- mets stable. Finished Carboplatin-remain on Herceptin
12/07 - Herceptin only
5/08 - Lung mets grew - tykerb and Navilbene. Reaction to Tykerb -9/08 Herceptin again
12/08 - Lung mets growing - xeloda.
8/09 - Given Zometa for precaution
10/09 - Lung mets back plus new ones. - Put back on Xeloda.
1/10 – Began short-term disability

2/10 –Lung mets growing - Gemzar
9/2010 – Scan show tumors in lungs growing. Put on Ixempra (every 3 weeks). MRI of the brain showed a brain bleed but it had stopped bleeding.


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Old 02-08-2010, 07:35 PM   #2
Darlene Denise
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Location: Virginia Beach, Virginia
Posts: 145
Re: Gemzar

Angela: I have been on Gemzar with Herceptin since November. I was initally given a lower dose (loved that, zero side effects). Now that my dose has been increased I do have some fatigue. My hair is still with me, it has thinned a little.

My onc says it has fewer side effects than Navelbine. I find it a walk in the park compared to Taxol/Carbo and Tykerb/Xeloda. I hope it is very easy and very effective for you!

I live in Virginia, but go to UNC for some of my treatment. I go down about every 2-3 months.

Good luck and I hope you post some positive results about being on the "Gem."

Darlene
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12/14/07 IDC ER- PR- HER2+++ LIVER METS AT DX CONFIRMED BY LIVER BIOPSY
01/14/08 2 AC TREATMENTS-NOT WORKING
02/04/08 13 TAXOL, CARBO, HERCEPTIN TREATMENT-EXCELLENT RESULTS!
05/12/08 HERCEPTIN EVERY 3 WKS
08/22/08 BRAIN METS! 8 <5MM
09/17/08 CYBERKNIFED BRAIN METS
10/20/08 BRAIN METS SHRINKING
12/29/08 BRAIN SCAN SHOWS 1 LESION GONE, 7 SHRINKING & STABLE, 1MM ? SPOT
01/16/09 LIVER REOCUR-XELODA/HERCEPTIN
03/02/09 BRAIN SCAN 2 LESIONS GONE, 5 STABLE, 1MM ? SPOT STILL A ?
3/27/09 REGRESSION OF 2 LIVER LESIONS XELODA & HERCEPTIN
06/08/09 STUPID BRAIN HAS 3 LESIONS
06/29/09 CYBERKNIFE
07/01/09 LIVER REGRESSION NO NEW METS
07/07/09 TYKERB XELODA HERCEPTIN
11/11/09 GEMZAR/HERCEPTIN FOR LIVER PROGRESSION
03/22/10 BRAIN MRI GOOD-3 SMALL NECROSIS LEFT FROM ORIG 11!!
03/26/10 CHANGE TO NAVELBINE/HERCEPTIN 3 LIVER LESIONS PROGRESSING IN SIZE
05/21/10 NAVELBINE/HERCEPTIN WORKING!
07/19/10 GOOD BRAIN MRI
08/20/10 LIVER PROGRESSION
09/08/10 TDM1 - NASHVILLE TN
01/10/11 LIVER RESPONDING TO TDM1
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Old 02-08-2010, 08:20 PM   #3
Rich66
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Location: South East Wisconsin
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Re: Gemzar

Gemzar link HERE

Scroll down to see some supplements that might help.

What was the issue with Tykerb?
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Mom's treatment history (link)
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Old 02-09-2010, 08:24 AM   #4
jml
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Posts: 415
Re: Gemzar

Hi Angela~

I have been on Gemzar on 2 occasions for recurrences to supraclav nodes and sternal nodes.
I tolerated it pretty well on both occassions, though did feel very fluish for ~3 days after the infusion, and I got a rash on my torso - hip bones, groin, shoulder blades. And you don't lose your hair.
The 1st time I was on this combo for ~4 mos, and the nodes resolved. Unfortunately, they came back about 6 months later, which we then addressed with 7 wks of Rads.
When I had the next recurrence in my sternal nodes, the Gemzar seemed to work initially, but didn't keep the nodes down for very long.

But remember, everyone is different and this drug could be The silver bullet for you. I've been on a bunch of different combos and found this combo to be pretty well tolerated. I hope this combo does the trick for you and that you tolerate the treatment well.
Keep us posted, okay?

ps-there's so much information to absorb about which supplements to take & when, on different treatment combos and how to manage all that. i have a very specific regimen that I follow, but under the direct instructions of a tcm. do what feels right for you and follow the advice that make sense to you.

Last edited by jml; 02-09-2010 at 08:26 AM.. Reason: typos
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