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Old 10-29-2009, 03:43 PM   #1
ammebarb
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About my sis....

It's been a while since I have given an update. My sister has finished her AC part of treatment and is halfway through her 12 weekly treatments of Taxol. She began to receive Herceptin along with the Taxol each three weeks of the month and then a Herceptin alone on the fourth week of the month. If all continues to go well, we think she will be finished with the chemo part of treatment before Christmas. She will continue with the Herceptin for the remainder of a year, will have a month off and then begin six weeks of radiation.

She is tolerating the Taxol a lot better than the AC, thank goodness. She told me today she is having some peripheral neuropathy, and the steroids she takes are giving her nasty heartburn. There is a good chance she will be able to take less of those, since she has had no hint of allergic reaction to the medium that carries the taxol at infusion.

She is beginning to get her hair back and said that she wasn't aware until now just how many directions it goes on her head! She is quite gray, but like me, is so grateful to have it be returning that color simply isn't mattering!

She is having the BRCA genetic testing done, probably tomorrow. We both have daughters, so findings could be important.

Watching her have to make this journey has been very painful for me, but I am also so very proud of her. She has a strength and determination and resiliency that amaze me....this is my "baby" sister, and she is one remarkable woman!

Wishing all of you the very best. I keep you all in my prayers.

Barb A.
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Old 10-29-2009, 04:17 PM   #2
tricia keegan
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Re: About my sis....

Barb, i had the same treatment as your sister and am glad she is getting thought it okay. I too found the taxol to be easier than a/c.
Good luck to her and you in getting through the rest of this. xx
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Dx July '05 IDC 1.9cm Triple positive 3/9 nodes positive
A/C X 4 ..Taxol/Herceptin x 12 wks then herceptin 1 yr
Rads x 36 ..oophorectomy August '06
Currently taking Arimidex..
June 2011 osteopenia/ zometa x1 yearly- stopped Zometa 2015 as Dexa show normal bone density.
Stopped Arimidex July 2014- Restarted Arimidex 2015 for a further two years on the advice of my Onc.
2014 Normal Dexa scan
2018 Mammo all clear, still NED!
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Old 10-29-2009, 04:23 PM   #3
Sheila
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Re: About my sis....

Barb
Glad to hear she is doing well...Nexium was a godsend when I was on Taxol for the heartburn. I know about the hair...mine is really salt and pepper, but I am so happy to have it, the color doesnt matter. Give your sis a big hug!!!!
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Sheila
Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications)
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression
6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin
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Old 10-29-2009, 07:29 PM   #4
sassy
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Re: About my sis....

Barb,

Hope your sis continues to do well. There were several of us on a previous post who noted that we had a lot of different crowns and cowlicks when our hair grew back. Maybe your sis is the same. No matter--it is great to have hair of any kind!
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dx age 45
DX 2/15/05 Stage IIb (at surgery)restaged IIIa
Left mast .9cm tumor 5 of 14 nodes
Triple Positive
4 DD A/C
12 Taxol/Herceptin
33Rads
Strange infect mast site one year aft surg, hosp 1 wk
Herceptin for total of 18 months
Lupron Monthly 4 yrs
Neurontin for aches, pains and hot flashes(It works!)
Ovaries removed 11/09 stop Lupron and Neurontin
Arimidex 6 yrs (tried Femara, no SE improvement)
Tried Exemestane-hips got so bad could hardly walk
Back to Arimidex for year seven
Zometa 2X Annual for 7years, Lasix
Stop Arimidex 5/13
Stop Zometa 7/13-Bi-lateral Stress Fractures in Femurs from Zometa
5/14 Start Tamoxifen
3/15 Stem cell transplant to stimulate femur bone growth/healing
5/15 Complete fracture of right femur/Titanium rods both femurs
9/16 Start Evista stopTamoxifen
3/17 Stop Evista--unwelcome side effects!
NED and no meds.......
14YEARS NED!
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Old 10-30-2009, 06:16 AM   #5
ammebarb
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Re: About my sis....

Thanks for responding ladies. My sis made me laugh when she told me she is shampooing and using cream rinse...just because she can! I will see her today for the first time in about a month and I'm anxious to see her new hair!

Do any of you who had six weeks of radiation have an tips for her about managing that? It's still a ways in the future, but I'll be starting to delve about it to prep mentally. There was some chance that she could do a week of radiation, twice a day, instead of the more conventional six weeks. Her surgeon was advocating that, but her oncologist likes the traditional better because there is more data on it's efficacy.

Thanks again for reading and being so willing to share with us. You are all Godsends!

Barb A.
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