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Old 05-07-2007, 07:49 PM   #1
LittleLegos
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Herceptin frequency - anyone do every 2 weeks?

Hi gals,

Right now I'm doing Taxol and Herceptin weekly and I really like doing it weekly. After my 12 weeks, I'm supposed to move to every three weeks for the Herceptin. I'm concerned I'll be getting 3 times as much drug. Has anyone done every two weeks with 2 times as much drug? That would be the same as my initial loading dose. Any thoughts?

Thanks so much.
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Little Legos, 34 yrs old
dd 3yrs, ds 6.5yrs

12/29/06 DCIS dx grade 2-3 with necrosis and focal early microinvasion
2/7/07 Partial Mastectomy and Sentinel Node Biopsy
2/18/07 dx .6cm IDC with DCIS 1.4cm, grade 2 ER-PR-HER2+++
neg nodes (3 taken), clean margins
3/20/07 Start 12 weekly Taxol - Herceptin, more Herceptin to follow
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Old 05-08-2007, 04:27 AM   #2
Mary Jo
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Hello,

I did NOT do herceptin every 2 weeks. I did taxol every 2 weeks. My first taxol treatment is when I had my loading dose (first treatment) of herceptin. I then received the herceptin every 3 weeks and taxol every 2. Occasionally, (I think twice) the herceptin and taxol fell on the same day. I had absolutely no problems receiving herceptin every 3 weeks and actually enjoyed receiving it that way. I have to travel a little more than an hour to my treatment facility and doing that every 3 weeks was plenty.

Hugs to you,

Mary Jo
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"Be still and know that I am God." Psalm 46:10

Dx. 6/24/05 age 45 Right Breast IDC
ER/PR. Neg., - Her2+++
RB Mast. - 7/28/05 - 4 cm. tumor
Margins clear - 1 microscopic cell 1 sent. node
No Vasucular Invasion
4 DD A/C - 4 DD Taxol & Herceptin
1 full year of Herceptin received every 3 weeks
28 rads
prophylactic Mast. 3/2/06

17 Years NED

<>< Romans 8:28
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Old 05-08-2007, 12:57 PM   #3
chrisy
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I did Herceptin every 3 weeks, but sometimes for my personal scheduling reasons, did a 2 week interval. I think either one would be fine - if you can tolerate the 3 week dose, it gives you more time to forget about infusions!
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Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial

5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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Old 05-08-2007, 05:06 PM   #4
Patb
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HI ALL

I do Herceptin every two weeks and always have. My oncologist said this
is great. I get twice the dose of one week and get it over an hour drip.
This gives me more free time rather than every week. They won't do three
weeks unless a trip is planned. I have done well on herceptin with no
side effects.

patb
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Diagnosed June, 06, Stage I, Grade3, ER+PR- Her2positive, No Nodes. A/C X 4. Radiation 33 with boost, Herceptin every two weeks until Nov.
07, Arimedex for 5 years. Mugas and Echo and chest xRay. Bone scan of whole Body, and Back of Brain and spine MRI.
CT scan of Lungs every six months
due to two small places. December
2009, bone scan due to bone pain.
Follow up test in 2010.
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