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Old 10-24-2006, 06:29 PM   #1
Mary Jo
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Anyone Know............?

Hi,

Being completely finished with treatment, I was just curious if anyone knows how long it takes for all drugs to be out of your system? Chemo ended Nov. 30, 2005 (A/C and Taxol) and herceptin ended October 11, 2006. I know herceptin is still in my system as I received it every 3 weeks. Just wondering how long that stuff stays in your system.

Thanks ~

Mary Jo
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"Be still and know that I am God." Psalm 46:10

Dx. 6/24/05 age 45 Right Breast IDC
ER/PR. Neg., - Her2+++
RB Mast. - 7/28/05 - 4 cm. tumor
Margins clear - 1 microscopic cell 1 sent. node
No Vasucular Invasion
4 DD A/C - 4 DD Taxol & Herceptin
1 full year of Herceptin received every 3 weeks
28 rads
prophylactic Mast. 3/2/06

17 Years NED

<>< Romans 8:28
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Old 10-24-2006, 06:45 PM   #2
Jackie
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Question

Mary Jo,

I finished with my chemo 11-05 and Herceptin 9-5-06. I am just now feeling like the Herceptin is out of my system. I do not know how long it is suppose to take.
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Stage II, Grade 2, DX 4-05
EP +, HER2 +++,
1 node+, 1.6cm
46 yrs. old at time of dx.
Completed Chemo 11-05
Completed 1 yr. Herceptin 8-06
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Old 10-24-2006, 08:19 PM   #3
Lani
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Lani

Herceptin is supposed to stay in your system for 6 months after the last dosage. Chemotherapy does not linger in your system, but some of its side effects can go on for months or forever in some.
Hope this helps!
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Old 10-25-2006, 07:33 AM   #4
panicked911
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My onc said that herceptain lasts three months and I should see an abatement in my side effects starting at about 1 month after and gardually subsiding over time IF they are attributable to the herceptain. Sh has her doubts.


Susanne
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Old 10-25-2006, 09:34 AM   #5
CPA
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Here is a quote directly from the prescribing info for Herceptin:

"In studies using a loading dose of 4 mg/kg followed by a weekly maintenance dose of 2 mg/kg, a mean half-life of 5.8 days (range = 1 to 32 days) was observed."

I seem to remember reading something else that said herceptin is actually detectible longer than initially thought. In any case, note the range for half-life. Different people appear to respond dramatically different to this drug. I am not sure if other chemo tx will impact the body's ability to eliminate the drug.

Hope this helps...
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