Bone mets; role the bone microenvironment plays in metastasis

Technical and 2002, but gives an idea how complex it all is, how inter realted, and how little is known.

What caught my attention was Endothelin being part of it all. As previously posted - in a trial (mice) Endothelin B receptor Ednrb expression was unpregulated by a factor of 10 in mice with low omega three high six v high omega three low six.

RB





http://grants.nih.gov/grants/guide/r...CA-03-013.html