Hi Donna; I'm on Navelbine/Herceptin for lymph node metastasis. I receive it weekly; side effects for me have been stomach pain and nausea if I don't take medication(Prilosec daily and I'm given Zofran before infusion, plus have pills to take at home but usually only need one additional pill the evening of treatment), muscle and joint aches along with mild cramping, some mild neuropathy of fingers and toes, and low red and white blood cell counts which result in tiredness and risk of infection. The side effects are pretty manageable, your mom's onc/nurses will fill you in on that; the trade-off is that Navelbine is a very effective drug with a proven track record. Good Luck, and keep us posted
<3 Lolly