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Old 07-23-2009, 09:51 AM   #1
bejuce
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Question My MRI Results Post Neoadjuvant Chemo

Hi everyone,

I just got my MRI report after almost completing my neo-adjuvant chemo regimen. Here's what it said:

"The breast tissue is predominantly fatty. There is persistent architectural distortion in the outer aspect of the right breast. The previously identified right axillary node is still present; however, the cortex appears thinner than prior exam. The abnormal enhancement seen on prior exam within the right breast is no longer present. There is still marked skin thickening."

The summary highlighted the fact that there is "no abnormal enhancement to suggest invasive malignancy." I also did a mammogram (showed microcalcifications but no area of concern around the biopsy marker) and an ultrasound (showed nothing, was normal).

So I'm hoping that the "architectural distortion" is just scar tissue. Before neo-adjuvant chemo, I had a huge (12 x 10 cm) area of enhancement that is now gone and my breast was predominantly dense (and is now fatty).

Has anyone else had this term "architectural distortion" come up? Any insights into my results will be appreciated! I'll be speaking with my surgeon this afternoon and will get more information then.

Thanks!!!
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ER+ (30%)/PR-/HER-2+, stage 3

Diagnosed on 02/18/09 at 38 with a huge 12x10 cm tumor, after a 6 month delay. Told I was too young and had no risk factors. Found swollen node during breastfeeding.
March-August 09: neo-adjuvant chemo, part of a trial at Stanford (4 DD A/C, 4 Taxotere with daily Tykerb), loading dose of Herceptin
08/12/09 - bye bye boobies (bilateral mastectomy)
08/24/09 - path report shows 100 % success in breast tissue (no cancer there, yay!), 98 % success in lymphatic invasion, and even though 11/13 nodes were still positive, > 95 % of the tumor in them was killed. Hoping for the best!
September-October 09: rads with daily Xeloda
02/25/10 - Cholecystectomy
05/27/10 - Bone scan clear
06/14/10 - CT scan clear, ovarian cyst found
07/27/10 - Done with Herceptin!
02/15/11 - MVA-BN HER-2 vaccine trial
03/15/11 - First CA 15-3: 12.7 and normal, yay!
10/01/11 - Bone scan and CT scan clear, fatty liver found
now on Tamoxifen and Aspirin


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Old 07-23-2009, 11:35 AM   #2
Rich66
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Location: South East Wisconsin
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If only Frank Llloyd Wright was around to chime in

I came across these which may or may not be relevant:
http://radiology.rsnajnls.org/cgi/co...tract/250/1/41

http://www.medscape.com/viewarticle/487388_2

http://books.google.com/books?id=p-u...esult&resnum=5
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