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Old 07-11-2010, 01:57 PM   #1
Delaney
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taxotere - iron band on chest?

Have had just 2 treatments of taxotere. My chest feels like there is an iron band wrapped tightly around it. Is this a normal side effect? Will this get worse as the treatments go on and has anyone any advice on how to ease it? I admire all the people who survived this particular chemo drug, its a tough one.
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Delaney, dx 2008 lumpectomy,mastectomy,a/c,paxitaxol, tyverb 1 yr.
dx 2010 mets lymph nodes, skin, lung. start taxotere/herceptin.
Stopped taxtere/herceptin, now on tyverb/xeloda.
Lung mets shrinking.
Back on Herceptin with T/X. Partial response.
Skin mets progressing. Radiation scheduled mid february 2011.
Spot found on hip - radiation to hip beginning mid February 2011.
Now trying Gemzar/Tyverb/Herceptin and Zometa.
CT scan Feb 2011 - lung clear!
Brain mets (specks) - radiation mid Feb.
Brain Scan June'11 - Clear
CT Scan June'11 - Good - skin met active - watch and wait.
Surgery to remove skin met. Surgery to back 2012, four titanium rods inserted. Skin mets reappear. On Navelbine, not working. 4 week washout, start Myocet for skin and lung mets August 2012. Brain scan clear despte intermittent blurry vision (something hiding? Am suspicious but hopeful. )On we go, glad to be here.
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Old 07-11-2010, 02:01 PM   #2
Rich66
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Re: taxotere - iron band on chest?

Have you reported this to your onc nurse or staff?
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Old 07-11-2010, 02:05 PM   #3
Emelie B
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Re: taxotere - iron band on chest?

Hi Delaney,
I had very bad rib pain while on was on Herceptin and Taxotere. They hurt so bad that we took x-rays of them to make sure there was no mets. I would say something to your nurse/onc as soon as you can.
Hope it gets better soon and hang in there,
Emelie
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Nov. 2006-IDC with Her2 +++
A/C for 3 rounds
Dec. 2006- Herceptin and Taxotere
March 2007-MRM with 8 of 14 lymph node involvement
May 2007-36 Rads
Sept. 2007- Stopped Herceptin
Jan. 2010- CT scan shows enlarged lymph nodes in sternum and lung involvement
Feb. 2010-PET scan shows mets to liver, lung, lymph nodes and bone
Feb. 2010- Started Herceptin/Taxol and Zometa
April 2010-PET scan clear. Herceptin and Zometa
June 2010- Stopped Herceptin continue Zometa and still NED
August 2010-Back on Herceptin and Zometa every 3 weeks
August 13, 2010- Had another port placed
August 24, 2010- PET scan clear. Herceptin and Zometa every three weeks
Nov. 2010-PET scan clear
Feb. 2011-Brain MRI clear
March 2011- PET scan clear
May 2011- PET scan clear
Sept. 2011- PET, Mammo, Bone Scan all clear- Herceptin only
March 2012-Recurrence in lungs and tumor around pota hepatis artery. Added Navelbine to herceptin
April 2012- Entered palliative care
June 5, 2012-Entered hospice care
Planning my memorial
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Old 07-11-2010, 03:08 PM   #4
tricia keegan
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Re: taxotere - iron band on chest?

Hi Delaney,

I had taxol which is of course similar, but did'nt experience this feeling at all. I'd agree with the other poster's to mention it, just in case it's an allergic reaction. x
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Dx July '05 IDC 1.9cm Triple positive 3/9 nodes positive
A/C X 4 ..Taxol/Herceptin x 12 wks then herceptin 1 yr
Rads x 36 ..oophorectomy August '06
Currently taking Arimidex..
June 2011 osteopenia/ zometa x1 yearly- stopped Zometa 2015 as Dexa show normal bone density.
Stopped Arimidex July 2014- Restarted Arimidex 2015 for a further two years on the advice of my Onc.
2014 Normal Dexa scan
2018 Mammo all clear, still NED!
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Old 07-11-2010, 03:23 PM   #5
karen z
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Re: taxotere - iron band on chest?

Hi. I, too, had taxol but didn't experience this feeling. I agree with other members who suggest discussing this with your team.
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Old 07-11-2010, 03:33 PM   #6
Rich66
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Re: taxotere - iron band on chest?

Chelee had a lung reaction to this, maybe she can share what it felt like.
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Old 07-11-2010, 05:02 PM   #7
Chelee
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Re: taxotere - iron band on chest?

Delaney, I had the same feeling when I did Taxotere. I can only explain it like I had this tightness straight across my chest...it was very uncomfortable. Both sides where my ribs were bothered me too. I told my onc and my bc surgeon and no one seemed concerned. They just told me it was due to the surgery (mastectomy) I had prior mixed with the reaction of the chemo hitting those areas. I didn't know what to think but it made me misrable. You asked if it will get worse...mine stayed about the same all thur each cycle and it did go away a couple months after I finished.

But always make sure your onc is aware of any side affects you experience. We all react differently. Taxotere can be a rough chemo but it does do the job and kicks butt. Hang in there.

Chelee
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DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.

Last edited by Chelee; 07-11-2010 at 10:41 PM.. Reason: Corrected spelling...
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Old 07-11-2010, 06:20 PM   #8
Pam P
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Re: taxotere - iron band on chest?

Does the tightness in your chest include shortness of breath? If so you might have developed pleural effustions from the taxotere. Yes, do investigate the symptoms with your onc. I had pleural effusions from the taxotere and it was very miserable.
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6/01 IBC er+ her2+stage IIIb; mastecomy
7/01 AC, taxol; radiation
2/02 tamoxifen
9/02 stage IV bone mets femara
1/03 taxotere/herceptin/aredia
6/03 herceptin, aredia & faslodex
1/04 navelbine, herceptin, aredia
2/05 herceptin/aredia
7/05 xeloda/herceptin/aredia
3/07 xeloda/tykerb/aredia
5/08 taxol/avastin/aredia
2/09 gemzar/herceptin/zometa
7/09 Taxol/Carbo/Herceptin, zometa
10/09 navelbine/herceptin & zometa
2/10 herceptin & tykerb & zometa
4/10 add xeloda &aromasin
10/10 dx with dermatomyiositis triggered by cancer
11/10 restart herceptin, tykerb, zometa
12/10 surgery-place rod in R femur to stabilize bone
1/11 radiation to R femur - 20 tx
2/11 2nd surgery - rod in Left femur
2/11 tx eribulen -- suspended dx brain mets
3/11 brain mets wbr 20 tx
4/11 halaven; discontine 8/11 not working
8/11 radiation to left femur 20 tx'
8-9/11 rad to lower spine
9/11 abraxane/herceptin/zometa
9/12 xeloda/herceptin/zometa
12/12 ablation of liver
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Old 07-11-2010, 10:22 PM   #9
BonnieR
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Re: taxotere - iron band on chest?

Not to overly alarm you but it could be a cardiac issue too. I hope you are in touch with a doctor asap.
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Post menopause
May 2007 Core biopsy, Rt breast
ER+, Pr-, HER2 +++, Grade 3
Ki-67: 90%
"suspicious area" left breast
Bilateral mastectomy, (NED on left) May 2007
Sentinel Node Neg
Stage 1, DCIS with microinvasion, 3 mm, mostly removed during the biopsy....
Femara (discontinued 7/07) Resumed 10/07
OncoType score 36 (July 07)
Began THC 7/26/07 (d/c taxol and carboplatin 10/07)
Began Herceptin alone 10/07
Finished Herceptin July /08
D/C Femara 4/10 (joint pain/trigger thumb!)
5/10 mistakenly dx with lung cancer. Middle rt lobe removed!
Aromasin started 5/10
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Old 07-12-2010, 03:11 AM   #10
Delaney
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Re: taxotere - iron band on chest?

thanks all for replying. The community nurse is visiting me today to take out the port stitches, I will mention it to her.Have no breathing problems and can still do housework, go walking, etc (in between sleeping, sleeping and sleeping!). Thanks so much.
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Delaney, dx 2008 lumpectomy,mastectomy,a/c,paxitaxol, tyverb 1 yr.
dx 2010 mets lymph nodes, skin, lung. start taxotere/herceptin.
Stopped taxtere/herceptin, now on tyverb/xeloda.
Lung mets shrinking.
Back on Herceptin with T/X. Partial response.
Skin mets progressing. Radiation scheduled mid february 2011.
Spot found on hip - radiation to hip beginning mid February 2011.
Now trying Gemzar/Tyverb/Herceptin and Zometa.
CT scan Feb 2011 - lung clear!
Brain mets (specks) - radiation mid Feb.
Brain Scan June'11 - Clear
CT Scan June'11 - Good - skin met active - watch and wait.
Surgery to remove skin met. Surgery to back 2012, four titanium rods inserted. Skin mets reappear. On Navelbine, not working. 4 week washout, start Myocet for skin and lung mets August 2012. Brain scan clear despte intermittent blurry vision (something hiding? Am suspicious but hopeful. )On we go, glad to be here.
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Old 07-12-2010, 03:30 AM   #11
Ellie F
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Re: taxotere - iron band on chest?

Hi Delaney
I had tightness and severe rib pain whilst on taxotere and herceptin. It took some time after completing the course to resolve. At times it was so bad I thought I had rib mets.

Ellie
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