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Old 07-08-2012, 12:32 PM   #1
sassy
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Location: Mountains of Virginia
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Re: arimidex side effects.

Debbie L. said:

"I've seen studies that report they can see "tenosynovial thickening" (or edema) and sometimes more fluid around the joints, on MRI looking for reasons for pain while on AIs."

I like to bring this up when questions about Arimidex side effects come up. My GP has had me on Lasix for several years to address the fluid that increases in the joints. It has made a significant difference in the amount of stiffness I experience. It has not "cured" the symptoms, but certainly an improvement.

At one point I cited a small study that supported this theory as an incidental finding in a study of cancer patients with heart issues using diuretics. The study found that those on AI's using the diuretics seemed to have less issue with joint stiffness.

I recommend discussing this with your onc and/or GP. For most, I would think giving it a try would not pose any problems and might prove helpful.
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Rhonda (Sassy)
dx age 45
DX 2/15/05 Stage IIb (at surgery)restaged IIIa
Left mast .9cm tumor 5 of 14 nodes
Triple Positive
4 DD A/C
12 Taxol/Herceptin
33Rads
Strange infect mast site one year aft surg, hosp 1 wk
Herceptin for total of 18 months
Lupron Monthly 4 yrs
Neurontin for aches, pains and hot flashes(It works!)
Ovaries removed 11/09 stop Lupron and Neurontin
Arimidex 6 yrs (tried Femara, no SE improvement)
Tried Exemestane-hips got so bad could hardly walk
Back to Arimidex for year seven
Zometa 2X Annual for 7years, Lasix
Stop Arimidex 5/13
Stop Zometa 7/13-Bi-lateral Stress Fractures in Femurs from Zometa
5/14 Start Tamoxifen
3/15 Stem cell transplant to stimulate femur bone growth/healing
5/15 Complete fracture of right femur/Titanium rods both femurs
9/16 Start Evista stopTamoxifen
3/17 Stop Evista--unwelcome side effects!
NED and no meds.......
14YEARS NED!
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Old 07-18-2012, 09:30 AM   #2
v-ness
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Re: arimidex side effects.

how soon did side effects kick in on Arimidex? i just started it last week after my onco had me do a bone density test. i don't feel anything different as of yet, and hope it continues that way. already aching from 2 yrs of tamoxifen.
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8/09 - IDC 1.8 cm triple positive, lumpectomy left breast
10/09 began chemo (taxotere & carboplatin) and weekly herceptin.
1/21/10 finished chemo, continued on herceptin every 3 weeks until 10/2010.
2/10 began 7 wks of radiation
6/10 mom dies of primary peritoneal ovarian cancer
8/10 got my last remaining ovary out
10/10 mammogram all clear
3/11 MRI shows 5 'spots' in right breast, largest 1 cm unidentifiable on US
needle biopsy proved the largest to be old inflamed cyst -phew!
7/10 switched to Arimidex
8/9 switched to Femara - allergic to arimidex
Femara made me lose hair quickly so switched to Aromasin
Aromasin made my hair fall out too and the bone pain was too much.
back on Tamoxifen 1/2013.
blood clot from trains and planes 5/2014 so on coumadin per onco for as long as i am on tamoxifen
tamoxifen was supposed to be up with my 5 yrs in may but my boyfriend was diagnosed with stage 4 colon cancer so i am staying on tamoxifen indefinitely because i want some ammo against BC, given the stress. lost my husband in only 10 wks in 2007 to stage 4 esophageal cancer.
cancer's screwing with another man i love
2/2016 - 6yrs in remission, off tamoxifen and off coumadin - yay!
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