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Old 04-04-2010, 11:18 AM   #1
Ellie F
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Join Date: Feb 2009
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Re: Tykerb through mastectomy??

Hi Lori
Sorry I have no personal information to offer however a couple of years ago a small trial (about 40 women )of tykerb for IBC was completed. The women on the trial continued tykerb throughout mastectomy surgery and had no problem with wound healing.
Sorry I can't locate the actual trial info to send you but I remember this information well.
Hope this might help.
Ellie
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Old 04-04-2010, 02:19 PM   #2
Chelee
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Location: Southern, CA
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Re: Tykerb through mastectomy??

Lori, I recurred last Sept. & started on Herceptin asap. But I was suppose to start chemo when we found out I had an "impending fracture" of my femur and needed surgery. I wanted to add something to the Herceptin due to the down time I would have with surgery & recovery. So I asked my onc if I could start on Tykerb? She was adamant that it would cause problems with my healing. After surgery I had an open hole from where the drain was and my incision--and it took forever to heal when I was only on Herceptin.

So I don't know if Tykerb would of slowed the healing or not...but my onc insist it would have. I also met this woman that is scheduled to have surgery on her shoulder and was told to stop her Tykerb by her onc. But now I question this advice since the trial Ellie mentioned had no problems with continuing Tykerb? Since a trial allowed it I would be more inclined to believe it's ok. Is there any other 2nd opinon onc's you have seen that you could call this wk before your surgery? Wish I could help more.

Chelee
__________________
DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
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