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Old 07-30-2007, 02:36 PM   #1
Alice
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After my last CT the tech that did the test made a comment that I should only have half of the contrast agent due to having only one kidney as the agents can be hard on the kidneys. He also stressed to make sure to drink enough liquids to flush it from my system.
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Old 07-30-2007, 04:56 PM   #2
Grace
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Thanks Stephanie,

When I recently had my MRI I was not asked about kidney or liver function problems! I hope this news gets out to all the people who should be hearing it! Wow!
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Old 07-30-2007, 05:06 PM   #3
chrisy
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Wow, scary stuff! I do get asked about liver/kidney problems and at some places they require current creatinine labs. They also insist on LOTS of water....after reading this, I think I'll strap on a gallon!
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June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial

5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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Old 07-30-2007, 07:56 PM   #4
tousled1
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I always get asked about kidney problems and am told to drink plenty of fluids after the scan.

I had a brain scan today and when they started to put the contrast in my vein collapsed and infiltrated. Thankfully, the tech was standing right there and was putting it in extra slow. My veins are really bad and they can only use my left arm due to lymphedema in the right arm. Well, I ended up getting stuck 3 times today and had to apply warm compresses to the hand where it infiltrated and keep arm elevated. The hand is fine now but in the future I will ask for an IV team member to access my veins. The last thing I need right now is an infection due to infiltration of the contrast.
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Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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Old 07-30-2007, 09:27 PM   #5
Lolly
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The tech who did my last abdominal CT w/contrast actually talked to me about this complication, asked if I'd ever had any problems with contrast, and really emphasized water, water, water.

I haven't had any problems so far, and have several scans per year since '99 which involve contrast. I drink lots of water anyway, and the techs always remind me to drink extra. The only side effect I notice after the contrast injections is tiredness that day, and sometimes the next, and being slightly headachey.

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Sept.'99 - Dx.Stage IIIB, IDC ER/PR-, HER2+++ by IHC, confirmed '04 by FISH. Left MRM, AC x's 4, Taxol x's 4, 33 Rads, finishing Tx May 2000. Jan.'01 - local/regional recurrence, Stage IV. Herceptin/Navelbine weekly till NED August 2001, then maintenance Herceptin. Right Mast. April 2002. Local/Regional recurrence April '04, Herceptin plus/minus chemo until May '07. Gemzar added from Feb.'07-April '07; Tykerb/Abraxane until August '07, back on Herceptin plus Taxotere and Xeloda Sept. '07. Stopped T/X Nov. '07, stopped Herceptin Dec. '07, started Avastin/Taxol/Carboplatin Dec. '07. Progression in chest skin, stopped TAC March '03, started radiation.

Herceptin has served as the "Backbone" of my treatment strategy for over 6 years, giving me great quality of life. In 2005, I was privileged to participate in the University of Washington/Seattle HER2 Vaccine Trial.
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