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Old 01-09-2007, 10:29 AM   #1
CLTann
Senior Member
 
Join Date: Oct 2005
Posts: 476
Joints ache probably Arimidex side effect

Dear Friends,

I have been on Arimidex more than 15 months. Lately, my joints (most of the right side) gave me sore and painful feeling, particularly when lying down. If I had sufficient sleep, the discomfor is much less. Do any of you have a similar problem? If so, how did you remedy the problem? Does a change to Femara help? Thanks for answering.
__________________
Ann

Stage 1 dx Sept 05
ER/PR positive HER2 +++ Grade 3
Invasive carcinoma 1 cm, no node involvement
Mastec Sept 05
Annual scans all negative, Oct 06
Postmenopause. Arimidex only since Sept 06, bone or muscle ache after 3 month
Off Arimidex, change to Femara 1/12-07, ache stopped
Sept 07 all tests negative, pass 2 year mark
Feb 08 continue doing well.
Sep 09 four year NED still on Femara.
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Old 01-09-2007, 10:40 AM   #2
Linda2
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Join Date: Dec 2006
Location: Millstadt, IL
Posts: 19
Dear Ann,

I started on Arimidex and had joint and bone pain so bad, could hardly walk. I told my Onc and she started me on Femara. I have been on Femara for 3 months and the pain is gone. I also workout on an elliptical and this seems to really help your joints. I do find that if I sit real long, it is hard to get up at first; your bones get really stiff.

I have no side effects with Femara like I did with Arimidex. Good luck with whatever you choose.
__________________
Linda2

DX 6/2005
Stage IIA, Grade I
ER/PR +, HER2 +++
Lumpectomy on Left breast 7/2005
No lymph nodes involved
4 cycles of A/C
12 weekly doses Taxol and Herceptin
33 Rads
Herceptin for one year ended 12/2006
Femara for 5 years
NED as of now
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Old 01-09-2007, 11:59 AM   #3
Hopeful
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Join Date: Aug 2006
Posts: 3,380
Dear Ann,

I started on Femara, and developed severe tinnitus within the first month. I had no joint pain. My onc switched me to Arimidex, to see if that would help. It took the tinnitus down a notch (it is related to estrogen deprivation, I believe, and Femara gets the levels down lower), however, on day 21 of Arimidex I noticed a sudden onset of joint pain and stiffness in the hands. These drugs definitely have side effects! It is a real case of "pick your poison." Good luck with your choice.

Hopeful
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Old 01-09-2007, 04:36 PM   #4
CLTann
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Join Date: Oct 2005
Posts: 476
Thanks for your answers. Linda2, what do you mean by elliptical? I guess the medication gives side effects varying with people. We just have to try out the least offense medicine.
__________________
Ann

Stage 1 dx Sept 05
ER/PR positive HER2 +++ Grade 3
Invasive carcinoma 1 cm, no node involvement
Mastec Sept 05
Annual scans all negative, Oct 06
Postmenopause. Arimidex only since Sept 06, bone or muscle ache after 3 month
Off Arimidex, change to Femara 1/12-07, ache stopped
Sept 07 all tests negative, pass 2 year mark
Feb 08 continue doing well.
Sep 09 four year NED still on Femara.
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Old 01-09-2007, 05:15 PM   #5
Linda2
Member
 
Join Date: Dec 2006
Location: Millstadt, IL
Posts: 19
An elliptical is sort of like a stair stepper and treadmill. You can work your arms and legs.

I think you are right. Everyone has different side effects from their medicine.

Wish you the best.
__________________
Linda2

DX 6/2005
Stage IIA, Grade I
ER/PR +, HER2 +++
Lumpectomy on Left breast 7/2005
No lymph nodes involved
4 cycles of A/C
12 weekly doses Taxol and Herceptin
33 Rads
Herceptin for one year ended 12/2006
Femara for 5 years
NED as of now
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Old 01-09-2007, 07:52 PM   #6
Jean
Senior Member
 
Join Date: Oct 2005
Location: New Jersey
Posts: 3,154
ONE YEAR on Arimidex....

Ann,
had a great deal of bone and joint pain. Esp. in the hip and hands.
Was so stiff in the morning but exercise helped. I also have an
eiliptical exercise machine at home and it is a wonderful piece of
euipment as it does not impact on the joints but allows you to have
a great workout.

I did stop taking the Arimidex after one year and now have been on
Femara since Sept. I am finding it much better and do not have
the heavy joint pain. But I do experience some mild ache and stiffness
after sitting in the car for a period of an hour or more. But once I
move around it goes away. I truly beleive that moving and exercise
are very important while on either AI. For me Femara seems to
be better.

Hope you feel better.
Jean
__________________
Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
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