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Old 10-03-2006, 03:52 PM   #1
Val Pfeiffer
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Hyperintense mass within pituitary--familiar to anyone?

Last week I got the MRI I wanted so badly. Today via fax I received the radiologist's report, but I haven't talked to my oncologist yet. (However I did fax it to my surgeon buddy who will see it later and call me tonight.)

Of course I have to talk to you all first! Below is the exact wording of the Impression on the report written by the doc who read the MRI. Doesn't sound like brain mets, but I'm interested in knowing whether this sounds like anything any of you have encountered:

1. No abnormalities of the brain stem or cerebral or cerebellar hemispheres identified.

2. Nonenhancing T1 and T2 hyperintense mass within the left paramedian aspect of the pituitary. Differential diagnosis would include a small hemorrhagic adenoma. Unlikely for this to represent an isolated pituitary metastasis. Recommend short term followup. Consider dedicated study of the pituitary.



thanks!
Val
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Dx 11/04, Age 42, ER-/PR-, HER2+++
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Mastectomy 3/05; Stage 3b, 9 cm tumor, 5/8+ nodes
3 more months weekly Herceptin, Taxol. Carboplatin
7/05 30 radiation treatments, IMRT planning approach
Started 1 year of Herceptin 9/05
9/06 Began quarterly triple doses Herceptin. Brain & breast MRIs semi annually.
* * * * * * * * * * * * * * * * * * * * * * * * * * *

6/08 Right breast, intraductal carcinoma, high nuclear grade associated with comedo necrosis; extensive diffusely involved the entire biopy specimen. ER+, PR-, Her2 unknown at this point, 07/08 mastectomy.
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Old 10-03-2006, 04:26 PM   #2
Lani
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microadenomas of the pituitary can be part of a triad

named Wermer's syndrome or MEA I(multiple endocrine adenomatosis type I)

My father may have it

They may also not be part of the triad

The other parts of the triad can be islet cell tumors of the pancreas (my dad has), tumors of the parathyroids, or other endocrine tumors.

Many people have this Wermer's syndrome or a variation of it without knowing it.

I may be completely off base, but you asked for info...
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Old 10-03-2006, 04:32 PM   #3
Val Pfeiffer
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Your description sounds like a completely different condition. That would be freaky to discover a whole new issue after getting a MRI to determine if I had brain mets. I was on PubMed just now and searched this condition with Her2 also in the search and came up with two articles (haven't read them yet).

Still looking for additional input on this if any of you have it. Of course my doc and my friend with give me advice, which I am sure will include more testing specifically focusing on the pituitary.
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BLOG:
http://valleygirlvnp.blogspot.com/
Dx 11/04, Age 42, ER-/PR-, HER2+++
3 months weekly Herceptin, Taxol. Carboplatin
Significant tumor shrinkage
Mastectomy 3/05; Stage 3b, 9 cm tumor, 5/8+ nodes
3 more months weekly Herceptin, Taxol. Carboplatin
7/05 30 radiation treatments, IMRT planning approach
Started 1 year of Herceptin 9/05
9/06 Began quarterly triple doses Herceptin. Brain & breast MRIs semi annually.
* * * * * * * * * * * * * * * * * * * * * * * * * * *

6/08 Right breast, intraductal carcinoma, high nuclear grade associated with comedo necrosis; extensive diffusely involved the entire biopy specimen. ER+, PR-, Her2 unknown at this point, 07/08 mastectomy.
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Old 10-03-2006, 05:54 PM   #4
Val Pfeiffer
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I just spoke with my surgeon about my MRI. He said that this mass is almost definitely not a distant met. He said it could have been there for awhile. His recommendation was to have a followup MRI in two months with special emphasis on the pituitary area. So unless my oncologist has a different idea, that's probably what I will recommend to him. :-)

Howe weird that something would show up unrelated to what we were looking for! I'm so glad that everything else looks clear.
__________________
BLOG:
http://valleygirlvnp.blogspot.com/
Dx 11/04, Age 42, ER-/PR-, HER2+++
3 months weekly Herceptin, Taxol. Carboplatin
Significant tumor shrinkage
Mastectomy 3/05; Stage 3b, 9 cm tumor, 5/8+ nodes
3 more months weekly Herceptin, Taxol. Carboplatin
7/05 30 radiation treatments, IMRT planning approach
Started 1 year of Herceptin 9/05
9/06 Began quarterly triple doses Herceptin. Brain & breast MRIs semi annually.
* * * * * * * * * * * * * * * * * * * * * * * * * * *

6/08 Right breast, intraductal carcinoma, high nuclear grade associated with comedo necrosis; extensive diffusely involved the entire biopy specimen. ER+, PR-, Her2 unknown at this point, 07/08 mastectomy.
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Old 10-03-2006, 06:38 PM   #5
sassy
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Glad for your good news Val.
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Last edited by sassy; 08-22-2011 at 08:55 AM..
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Old 10-03-2006, 09:44 PM   #6
tousled1
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Val,

Glad that the MRI is all clear for mets. I'm sure they will watch the pituitary very closely but I would doubt seriously that it's cancer.
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Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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