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Old 08-28-2006, 10:35 PM   #1
Cheryl E
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Red face Decaf green tea?

Was wondering if anyone knows of a brand of pre-brewed DECAF green tea (without sweeteners) that I can take from the store shelf and put directly into my frig. I am very sensitive to the caffeine in regular green tea. It keeps me awake at night, even if I drink only a few glasses before 3:00 pm. I have never been a coffee or coke drinker. I have decaf green tea bags, but I never seem to get around to brewing it, then icing it.

Cheryl
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Old 08-29-2006, 12:30 AM   #2
Tom
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Cheryl,

I know you want ready to go tea, but the fresh brewed is far better. There aren't tons of chemicals and preservatives in it. I went out and bought a big 2 1/2 gallon plastic container that fits neatly in the fridge, and has a spring loaded spout on one end. The trick is to brew up a huge load of the stuff at one time, so you don't mind the work. Try Harris brand decaf green tea in bags. I put 24 bags in about 2 gallons of water that has just been shut down from a full boil. Add the grated rind (zest) of one large navel orange to give you a kick of d-limonene as well. Let it steep for about half and hour, then cool with ice before putting in the fridge. You can add honey if you like to sweeten it up a bit. This will last you a while, and give you the benefits of the EGCG in the tea, which is a naturally occuring tyrosine kinase inhibitor, having the effect of blocking trans-membrane cell signalling associated with HER2 cell surface protein production.

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Old 08-29-2006, 01:18 AM   #3
karenann
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Tom,

That sounds great!! I am going to go out tomorrow and get some of that green tea. The orange zest sounds great, too.

Thanks for the wonderful idea.

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Old 08-29-2006, 08:16 AM   #4
Barbara2
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Tyrosine Kinase Inhibitor/Tea instead of water?

Thanks for the information and good tips, Tom. I didn't realize tea was a tyrosine kinase inhibitor; that is great. I used to brew a batch in the way you had suggested, but have slacked off recently to drink the bottled tea that you can find in the store. (Not green tea, though; the only bottled green tea I've found has sweetners added to them.) After reading this, I will start making more tea again.

In regards to the tea bags, someone here had suggested the Salada decaffeinated green tea, which is processed with water and effervescence, so that is what I buy. I'll also look to see if the Harris brand is offered in the stores.

I drink tea throughout the day instead of water. I've read where tea, coffee, etc shouldn't replace the amount of water you drink, but I wonder if those of us that are battling cancer should focus on the tea, anyway.

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Old 08-29-2006, 09:57 AM   #5
Tom
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I have been giving Mom buckets of green tea since we first found out she was HER2+. It's nice to be able to get somebody to drinks lots of water, but they won't always do it. The bottled teas are total garbage from what I have seen. They are all sweetened with high fructose corn syrup, are generally watered down. You hold them up to the light, and can barely see any tea coloring to them.

Another advantage to the homebrewed, is that you can adjust your sweetening level/method to meet your own tastes. I began adding the orange zest to get some added d-limonene into Mom, as there was not that much available (10mg) in each Life Extension brand 100mg CoQ-10 capsule I was giving her. However, you may not have noticed that Life Extension has released a high concentration version (1000mg) of d-limonene by itself, that is offered as a treatment for severe GERD. I now use one of those each day as an added source of d-limonene for Mom. Additionally, a friend who has had GERD for years, has tried this new product, and has completely stopped taking his Rx drugs for the same problem. He swears by the d-limonene.

Many people do not find green tea to their liking, but if you add a few fresh cloves to the orange zest as well, it starts to roughly approach the flavor of Constant Comment tea, which many people enjoy.

Epigallocatechin-3-gallate inhibits activation of HER-2/neu and downstream signaling pathways in human head and neck and breast carcinoma cells.

Masuda M, Suzui M, Lim JT, Weinstein IB.

Herbert Irving Comprehensive Cancer Center, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA.

Overexpression of the HER-2/neu receptor (HER-2) is associated with a poor prognosis in patients with breast carcinoma and also in patients with head and neck squamous cell carcinoma (HNSCC). In a previous study on HNSCC cell lines, we found that epigalocathechin-3-gallate (EGCG), a major biologically active component of green tea, inhibited activation of the epidermal growth factor receptor (EGFR) and thereby inhibited EGFR-related downstream signaling pathways in HNSCC cells. In the present study, we examined the effects of EGCG on activation of the HER-2 receptor in human HNSCC and breast carcinoma cell lines that display constitutive activation of HER-2. Treatment of these cells with 10 or 30 microg of EGCG, respectively, doses that cause 50% inhibition of growth, markedly inhibited the phosphorylation of HER-2 in both cell lines. This was associated with inhibition of Stat3 activation, inhibition of c-fos and cyclin D1 promoter activity, and decreased cellular levels of the cyclin D1 and Bcl-XL proteins. Although these concentrations of EGCG are quite high, we found that concentrations of 0.1-1.0 microg/ml, which are in the range of plasma concentrations after administering a single oral dose of EGCG or a green tea extract, markedly enhanced the sensitivity of both types of cell lines to growth inhibition by Taxol, a drug frequently used in the treatment of breast carcinoma and HNSCC. These results, taken together with previous evidence that EGCG also inhibits activation of the EGFR in carcinoma cells, suggest that EGCG may be useful in treating cases of breast carcinoma and HNSCC in which activation of the EGFR and/or HER-2 plays important roles in tumor survival and growth.

Here's another link:

http://cancerres.aacrjournals.org/cg.../full/62/3/652

Here's some d-limonene info:

http://cancerres.aacrjournals.org/cg.../full/62/3/652


Cheers,
Tom
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Old 08-29-2006, 03:22 PM   #6
Tom
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Foot note

I forgot to mention one small point. I love lemon in my tea, but I read that citric acid in lemon juice reduces the positive effects that EGCG have, so lemon is a no-no right in the tea. I'll look for that info and post it if I can find it.
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