 |
08-20-2006, 04:54 PM
|
#1
|
|
Senior Member
Join Date: Feb 2006
Location: Southern, CA
Posts: 2,511
|
Herceptin 3wk dose & burising?
I usually get my hercepten weekly. But a while ago I thought I would try the 3 week dose since its easier...less appts.
I noticed I burised quite easily after this 3 weeks dose? I had burises every where on my arms. Any place I barely bumped had one. But with the weekly...I never noticed that. I even showed my infusion nurse and she asked what happened to me. lol
Anyone else had this problem?
Chelee
__________________
DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
|
|
|
|
08-20-2006, 05:50 PM
|
#2
|
|
Senior Member
Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
|
Hi Chelee,
Hmmm. I haven't noticed this with 3 weekly Herceptin; I've been on this regimen for over a year.
I did notice it at times when I was getting TCH but this seemed to be related to how high/low my platelets were. It sure was embarassing - my poor husband was afraid people would think he was mistreating me LOL!
Do you get CBC (blood test) before your treatment? Maybe this is the culprit. My platelet level fluctuates and is usually towards the low end of normal with the amount of which I attribute to taking a lot of fish oil.
__________________
Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial
5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
|
|
|
|
|
08-20-2006, 07:12 PM
|
#3
|
|
Senior Member
Join Date: Feb 2006
Location: Southern, CA
Posts: 2,511
|
Chrisy, I know my infusion nurse asked what I had been doing because she had NEVER ran across this before. So her first thought is to check my blood work. She said as you did...that is usually a sign of low platelets which I was NOT on any other chemo or drugs other then herceptin.
In fact on my LAST full cycle chemo back in June my platelets hit a all time low of 32. So there was an explanation for the bruising at that time.
But this last time I have NO idea why so many bruises? The only thing I did different was get the 3 wk dose of herceptin. I felt fine...didn't notice anything different from my WEEKLY doses expect that one thing? Maybe it was a freak thing. I don't think I was bouncing off the walls and I just did not notice it. LOL  The only thing a TAD low was my RBC...but not enough to make any difference like that.
I was just curious if it was only me...next time I do the 3 wk dose I am going to pay close attention to that just to see if it happens again. Thanks Christy. (Tell your hubby to behave himself...no hitting.) LOL...poor guy!
Chelee
__________________
DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
|
|
|
|
|
08-21-2006, 05:57 AM
|
#4
|
|
Senior Member
Join Date: Oct 2005
Location: New Jersey
Posts: 3,154
|
Hi Chelee,
I noticed one or two bruises - but I think it is TCH.....I am still on the wkly herceptin. Will update you when I start the 3wkly which should start in Sept.
Hope your feeling well.
All good wishes,
Jean
|
|
|
|
|
08-21-2006, 02:11 PM
|
#5
|
|
Senior Member
Join Date: Nov 2005
Location: Ireland
Posts: 3,463
|
Me Too!
Hi Chelee
I had'nt connected this to herceptin before now until Ii read your post.Lately I do seem to bruise more easily and last week I had an oophorectomy and although some bruising is expected,mine is extremly excessive.I'm dark purple from my stomach down to my thigh! I usually swim a lot but won't be getting into a swimsuit for some time by the look of it! I'm wondering now if herceptin has something to do with it having read your post.
Tricia
|
|
|
|
|
08-23-2006, 01:39 AM
|
#6
|
|
Senior Member
Join Date: Feb 2006
Location: Southern, CA
Posts: 2,511
|
Hi Tricia, Finally, someone else that noticed this problem. I was sure it was herceptin...but it seemed like the bursing had to be from the herceptin since it happened right after I got the 3 weeks dose. I am back on the weekly and it does seem better. But I still think herceptin did cause my burising with the higher dose.
Sounds like you had some bad bruising too. I realize that would cause you to have some bruising...but as you stated...sounds worse then would be expected. I think that is something most on herceptin would not put two and two together since we all get a bruise now and then. Yours might not be from herceptin...but makes you wonder huh. (Something to think about?)
Jean, Your right...being on TCH would make it difficult to know for sure which is the cause of it? I know when I was on TCH...I did notice bruising too. So with you...we WILL have to wait till your done and just doing herceptin...which won't be long now. You only have one more to do...right? Almost done...yea.
Sending you warm healing thoughts Jean...it won't be long now. Hang in there.
Chelee
__________________
DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
|
|
|
|
Posting Rules
|
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts
HTML code is Off
|
|
|
All times are GMT -7. The time now is 02:53 PM.
|
Linear Mode
