Blc2 is a prognosticator for IDC [Archive]

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Hopeful

07-23-2007, 07:28 AM

The article: http://www.breastcancersource.com/breastcancersourcehcp/6096_27859___.aspx

The abstract: http://annonc.oxfordjournals.org/cgi/content/abstract/18/6/1004

Of interest:

"Results: In the entire series, the Bcl2 variable was an independent predictor of clinical outcome, and its prognostic independence was maintained when lymph node-negative and -positive patients were considered separately. In this regard, of particular interest was the observation of a subgroup of node-negative breast cancer patients with a negative Bcl2 immunostaining, who had a very high probability of relapse or death (respectively about five and seven times greater than patients with a positive Bcl2 immunostaining). Moreover, the Bcl2 variable retained prognostic significance also in subgroups of patients treated with either adjuvant endocrine therapy or chemotherapy."


Hopeful

Mary Jo

07-23-2007, 07:36 AM

Thanks for posting this Hopeful. As most of the articles posted here I don't understand most of them really and have no idea how I would find out half the stuff mentioned in them as it pertains to my particular cancer BUT this article caused me to chuckle anyway. There was a quote by a "team" from the "University of Bologna." LOL LOL LOL! I got a kick out of that.

Have a great day and thanks to everyone who stays on top of this world called breast cancer. You are a blessing to all of us.

Mary Jo

jhandley

07-23-2007, 09:06 PM

Co-enzyme Q10 restores the bcl 2 gene to its normal fuction. Search under bcl-2 and Q10.
cheers
jackie