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Old 02-01-2008, 02:01 PM   #1
debski
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Smile splits in finger ends?

I know it's a small price to pay but they are surprisingly inconvenient and painful.

Anyone else got them?
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Old 02-01-2008, 02:48 PM   #2
Gerri
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Yes, yes, yes. I'm about 10 months out of Herceptin and STILL get them occaissonally. They bleed and hurt like crazy! Fortunately they heal over in a few days - until the next time. Very annoying, but like you said worth it in the long run.
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Gerri
Dx: 11/23/05, Lumpectomy 12/12/05
Tumor 2.2 cm, Stage II, Grade 3, Sentinel Node biopsy negative
ER+ (30%) /PR+ (50%), HER2+++
AC X 4 dose dense, Taxol X 4 dose dense
Herceptin started with 2nd Taxol, given weekly until chemo done
then given every 3 weeks for one year ending on March 16, 2007
Radiation 30 treatments
Tamoxifen - 2 yrs (pre-menopausal)
May 2008 - Feb 2012 Femara
Aug 2008 - Feb 2012 Zometa every 6 months
March 2012 - Stop Femara, now Evista for bone strengthening
**********
Enjoy the little things, for one day you may look
back and realize they were the big things.
- Robert Brault
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Old 02-01-2008, 02:53 PM   #3
Brenda_D
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Do you mean at the sides of your fingertips, where the nail and flesh meet? I get those quite a lot now. Never did before, and yes, they hurt.
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12/12/06- IDC Stage III, 4x A/C, 35 rads, Herceptin 1 year
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Old 02-01-2008, 03:06 PM   #4
Gerri
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Yep, they split at the sides. I have this weird ointment that I bought several years ago - "Beaver Balm", it comes in a tin - and I put it on them at night. This seems to help the cracks heal faster.
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Gerri
Dx: 11/23/05, Lumpectomy 12/12/05
Tumor 2.2 cm, Stage II, Grade 3, Sentinel Node biopsy negative
ER+ (30%) /PR+ (50%), HER2+++
AC X 4 dose dense, Taxol X 4 dose dense
Herceptin started with 2nd Taxol, given weekly until chemo done
then given every 3 weeks for one year ending on March 16, 2007
Radiation 30 treatments
Tamoxifen - 2 yrs (pre-menopausal)
May 2008 - Feb 2012 Femara
Aug 2008 - Feb 2012 Zometa every 6 months
March 2012 - Stop Femara, now Evista for bone strengthening
**********
Enjoy the little things, for one day you may look
back and realize they were the big things.
- Robert Brault
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Old 02-01-2008, 03:20 PM   #5
harrie
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I found tea tree oil to be very beneficial.
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*** MARYANNE *** aka HARRIECANARIE

1993: right side DCIS, lumpectomy, rads
1999: left side DCIS, lumpectomy, rads, tamoxifen

2006:
BRCA 2 positive
Stage I, invasive DCIS (6mm x 5mm)
Grade: intermediate
sentinal node biopsy: neg
HER2/neu amplified 4.7
ER+/PR+
TOPO II neg
Oncotype dx 20
Bilat mastectomy with DIEP flap reconstruction
oophorectomy

2007:
6 cycles TCH (taxotere, carboplatin, herceptin)
finished 1 yr herceptin 05/07
Arimidex, stopped after almost 1 yr
Femara
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Old 02-01-2008, 04:44 PM   #6
R.B.
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Cracked heels and fingers is cited by some a possible indication of a fat imbalance. Michael A Schmidt - Smart Fats

Please discuss dietary change with your medical advisor.

I have been asking for a long time if herceptin intervenes in fat pathways. Many of the side effects cited could suggest that is a possibility.

This thread might be of interest.


http://her2support.org/vbulletin/sho...ght=greek+diet
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Old 02-02-2008, 07:44 AM   #7
doh2pa
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Yes, they are a pain, aren't they, especially worse in the cold weather. I found keeping them covered with those special finger band aids helped them to heal faster.
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Donna
Diagnosed 2/04 - Invasive ductal - no clean margins
node negative - er+pr+, her2++
Mastectomy 4/04 - 4 rounds AC
9/05 - mets to liver treated with carbo/ixabipelone/herceptin
3/06 - complete remission
9/06 - new liver mets, starting Taxotere/Herceptin
1/07 -Liver mets stable, staying on Herceptin
5/07 - Liver, lung progression - starting T/X
12/07 - Liver, lung progression - starting weekly Navilbene/Herceptin
4/08 - Liver progression - started Abraxane, Carbo, Tykerb and Herceptin
7/08 - Liver Progression - started Gemzar, Avastin and Tykerb
10/08 - Liver progression - starting Doxil
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Old 02-02-2008, 09:07 AM   #8
BethC
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Yes, I get them every winter. They are really annoying and painful for such a small thing. The year my twins were born was the worst - from all the hand washing, etc. Anyway, the thing that helps me is to blob on the neosporin and cover it with a band aid for a few days. Also, I try to keep my hands out of the water unnecessarily (washing pans, etc.) I hope you find some relief!!
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DX 9-19-07 at age 40
DCIS, Inv. Duct. Car. 3 cm
Positive lymph node biopsy
Er+Pr+Her+++
Carboplatin/Taxotere/Herceptin
10-1-07 -- 1-16-08
Herceptin every 3 weeks until 9/24/08
Lump. and node dissection 2-12-08
BRCA1 and 2 negative
30 rads finished 4-23-08
oophorectomy 5-6-08
Femara started 5/25/08
Zometa for osteoporosis every 6 mo. started 9-24-08

Married 16 years!
3 kids - daughter (10), twin sons (7)
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Old 02-02-2008, 01:29 PM   #9
Jean
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Oh Yes,
they hurt and are painful, it seems that once open you hit your finger against everything....oooch...

Found the following and it helped:

1. Wear the best rubber gloves to protect your hands from water when washing dishes, etc. Keep your hands out of water.

2. Now this was a surprise: Use Balmex on hands and fill in the cracks with Balmex especially at night, so the cream has hours to heal. This is a
zinc oxide diaper rash cream, with Aloe and vit. e. Works Great...can be purchased in any CVS store.

Kind Regards,
Jean
PS Also great for plain old red winter hands.
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Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
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Old 02-02-2008, 09:24 PM   #10
hutchibk
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Thanks for the Balmex tip, Jean! I need it, I have two paper cuts on fingertips that won't heal due to Tykerb/Xeloda. I will try that tomorrow!
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Brenda

NOV 2012 - 9 yr anniversary
JULY 2012 - 7 yr anniversary stage IV (of 50...)

Nov'03~ dX stage 2B
Dec'03~
Rt side mastectomy, Her2+, ER/PR+, 10 nodes out, one node positive
Jan'04~
Taxotere/Adria/Cytoxan x 6, NED, no Rads, Tamox. 1 year, Arimadex 3 mo., NED 14 mo.
Sept'05~
micro mets lungs/chest nodes/underarm node, Switched to Aromasin, T/C/H x 7, NED 6 months - Herceptin only
Aug'06~
micro mets chest nodes, & bone spot @ C3 neck, Added Taxol to Herceptin
Feb'07~ Genetic testing, BRCA 1&2 neg

Apr'07~
MRI - two 9mm brain mets & 5 punctates, new left chest met, & small increase of bone spot C3 neck, Stopped Aromasin
May'07~
Started Tykerb/Xeloda, no WBR for now
June'07~
MRI - stable brain mets, no new mets, 9mm spots less enhanced, CA15.3 down 45.5 to 9.3 in 10 wks, Ty/Xel working magic!
Aug'07~
MRI - brain mets shrunk half, NO NEW BRAIN METS!!, TMs stable @ 9.2
Oct'07~
PET/CT & MRI show NED
Apr'08~
scans still show NED in the head, small bone spot on right iliac crest (rear pelvic bone)
Sept'08~
MRI shows activity in brain mets, completed 5 fractions/5 consecutive days of IMRT to zap the pesky buggers
Oct'08~
dropped Xeloda, switched to tri-weekly Herceptin in combo with Tykerb, extend to tri-monthly Zometa infusion
Dec'08~
Brain MRI- 4 spots reduced to punctate size, large spot shrunk by 3mm, CT of torso clear/pelvis spot stable
June'09~
new 3-4mm left cerrebellar spot zapped with IMRT targeted rads
Sept'09~
new 6mm & 1 cm spots in pituitary/optic chiasm area. Rx= 25 days of 3D conformal fractionated targeted IMRT to the tumors.
Oct'09~
25 days of low dose 3D conformal fractionated targeted IMRT to the bone mets spot on rt. iliac crest that have been watching for 2 years. Added daily Aromasin back into treatment regimen.
Apr'10~ Brain MRI clear! But, see new small spot on adrenal gland. Change from Aromasin back to Tamoxifen.
June'10~ Tumor markers (CA15.3) dropped from 37 to 23 after one month on Tamoxifen. Continue to monitor adrenal gland spot. Remain on Tykerb/Herceptin/Tamoxifen.
Nov'10~ Radiate positive mediastinal node that was pressing on recurrent laryngeal nerve, causing paralyzed larynx and a funny voice.
Jan'11~ MRI shows possible activity or perhaps just scar tissue/necrotic increase on 3 previously treated brain spots and a pituitary spot. 5 days of IMRT on 4 spots.
Feb'11~ Enrolled in T-DM1 EAP in Denver, first treatment March 25, 2011.
Mar'11~ Finally started T-DM1 EAP in Denver at Rocky Mountain Cancer Center/Rose on Mar. 25... hallelujah.

"I would rather be anecdotally alive than statistically dead."
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Old 02-06-2008, 01:07 PM   #11
mabrooks
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Fingers sore and cracked and my nails are broken below the skin line with ridges and splits. Will try the Balmex, thanks.
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3/16/07 dx DCIS - microinvasion - grade 1
lumpectomy - mammosite radiation treatment 4/07
Estrogen+ and Progestrone+ and HER2neu 3+
Started Herceptin 5/07 once every three weeks
Was On Arimidex -switched to Femara
Oncotype 23
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Old 02-07-2008, 09:56 AM   #12
debski
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well I know it sounds mean but I 'm glad it's not just me!

Yeah they split at the edges of the nails at the tip of the finger-even if I just hit them lightly against something.

Fat metabolism? Interesting one-I have been on a very healthy diet since diagnosis-so my body should be able to cope unless,as you say there is some metabolic interference.

I have considered sticking superglue on the cracks!!!!!!!!!!!! Not been brave enough yet though.
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Old 07-18-2008, 10:36 AM   #13
Mary Jeanne Phillips
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Humecta pd is the best prescription for all the symptoms of nail beds and finger splits. It is 41% urea. May have to have a prescription but after using everything a friend with the side effect from Tykerb has found that as an answer.
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Old 07-19-2008, 08:55 AM   #14
Lani
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looked up product info on balmex for diaper rash and found

(my)NOTE--THOSE WHO ARE HER2+ER+ who are trying to avoid parabans may not realize that there are both methyl and
propylparabens in this cream


NEW! BALMEX® with ActiveGuard™

New Balmex® with patented ActivGuard™ formula works on contact in two ways:
1. Clinically proven to reduce redness in ONE diaper
change.
2. New ActivGuard protection to neutralize irritants in
dirty diapers.
Contains doctor-recommended zinc oxide plus three soothing botanicals and skin nourishing vitamins B5 and E to help soothe and treat diaper rash, while moisturizing and nourishing baby's irritated skin.
Provides a protective barrier against wetness and irritants to help prevent rashes from getting worse.
Goes on smooth, wipes off easily and has a pleasant, fresh scent.
How to use:
Change wet and soiled diapers promptly. Clean the diaper area, and allow skin to dry. Apply BALMEX® Zinc Oxide Diaper Rash Cream liberally as often as necessary, with each diaper change, and especially before bed or anytime when exposure to wet diapers may be prolonged.

Warnings:
For external use only
When using this product avoid contact with eyes.
Stop use and ask a doctor if condition worsens or does not improve within 7 days.
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Ingredients:
ACTIVE INGREDIENT: Zinc Oxide (11.3%)

ALSO CONTAINS: beeswax, benzoic acid, dimethicone, fragrance, glycine soja (soybean) oil, magnesium aspartate, methylparaben, microcrystalline wax, mineral oil, oenothera biennis (evening primrose) seed extract, olea europaea (olive) leaf extract, panthenol, potassium aspartate, potassium hydroxide, propylene glycol, propylparaben, sarcosine, sodium cocoyl amino acids, sorbitan sesquioleate, synthetic beeswax, tocopherol, water
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Old 07-19-2008, 10:22 AM   #15
SoCalGal
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My nails are a mess - I have to keep them polished every 3 days and they still break/peel/crack.

What I for sure realized is that when I cut them very short I get these cracks on the sides of my thumbs. If I keep the nail slightly long (and I mean slight since they don't really grow much) the cracks don't appear. Also - wearing gloves for almost everything is a MUST. Hands get tender from the most stupid tasks.

Nails are so soft I can't put on a necklace - can't pull the spring hinge back on the clasp - it just slices the nail. Not complaining - just saying as an example of how weak my nails are.

Perhaps I need a jewelry assistant?

I take this as a sign that the meds are working if they are producing side effects.

I don't know about avoiding parabans - what are they and what can they do to us?

Flori
__________________
1996 cancer WTF?! 1.3 cm lumpectomy Er/Pr neg. Her2+ (20nodes NEGATIVE) did CMF + rads. NED.
2002 recurrence. Bilateral mastectomy w/TFL autologous recon. Then ACx2. Skin lymphatic rash. Taxotere w/Herceptin x4. Herceptin/Xeloda. Finally stops spreading.
2003 - Back to surgery, remove skin mets, and will have surgery one week later when pathology can confirm margins.
‘03 latisimus dorsi flap to remove skin mets. CLEAN MARGINS. Continue single agent Herceptin thru 4/04. NED.
‘04 '05 & 06 tiny recurrences - scar line. surgery to cut out. NED each time.
1/2006 Rads again, to scar line. NED.

3/07 Heartbreaking news - mets! lungs.sternum. Try Tykerb/Xeloda. Tykerb/Carbo/Gemzar. Switch Oncs.
12/07 Herceptin.Tykerb. Markers go stable.
2/8/08 gamma knife 13mm stupid brain met.
3/08 Herceptin/tykerb/avastin/zometa.
3/09 brain NED. Lungs STABLE.
4/09 attack sternum (10 daysPHOTONS.5 days ELECTRONS)
9/09 MARKERS normal!
3/10 PET/CT=manubrium intensely metabolically active but stable. NEDhead.
Wash out 5/10 for tdm1 but 6/10 CT STABLE, PET improving. Markers normal. Brain NED. Resume just Herceptin plus ZOMETA
Dec 2010 Brain NED, lungs/sternum stable. markers normal.
MAR 2011 stop Herceptin/allergy! Go back on Tykerb and switch to Xgeva.
May-Aug 2011 Tykerb Herceptin Xgeva.
Sept 2011 Tykerb, Herceptin, Zometa, Avastin.
April 2012 sketchy drug trial in NYC. 6 weeks later I’m NED!
OCT 2012 PET/CT shows a bunch of freakin’ progression. Back to LA and Herceptin.avastin.zometa.
12/20/12 add in PERJETA!
March 2013 – 5 YEARS POST continue HAPZ
APRIL 2013 - 6 yrs stage 4. "FAILED" PETscan on 4/2/13
May 2013: rePetted - improvement in lungs, left adrenal stable, right 6th rib inactive, (must be PERJETA avastin) sternum and L1 fruckin'worsen. Drop zometa. ADD Xgeva. Doc says get rads consultant for L1 and possible biopsy of L1. I say, no thanks, doc. Lets see what xgeva brings to the table first. It's summer.
June-August 2013HAPX Herceptin Avastin Perjeta xgeva.
Sept - now - on chemo hold for calming tummy we hope. Markers stable for 2 months.
Nov 2013 - Herceptin-Perjeta-Avastin-Xgeva (collageneous colitis, which explains tummy probs, added Entocort)
December '13 BRAIN MRI ned in da head.
Jan 2014: CONTINUING on HAPX…
FEB 2014 PetCT clinical “impression”: 1. newbie nodule - SUV 1.5 right apical nodule, mildly hypermetabolic “suggestive” of worsening neoplastic lesion. 2. moderate worsening of the sternum – SUV 5.6 from 3.8
3. increasing sclerosis & decreasing activity of L1 met “suggests” mild healing. (SUV 9.4 v 12.1 in May ‘13)
4. scattered lung nodules, up to 5mm in size = stable, no increased activity
5. other small scattered sclerotic lesions, one in right iliac and one in thoracic vertebral body similar in appearance to L1 without PET activity and not clearly pathologic
APRIL 2014 - 6 YRS POST GAMMA ZAP, 7 YRS MBC & 18 YEARS FROM ORIGINAL DX!
October 2014: hold avastin, continue HPX
Feb 2015 Cancer you lost. NEDHEAD 7 years post gamma zap miracle, 8 years ST4, +19 yrs original diagnosis.
Continue HPX. Adding back Avastin
Nov 2015 pet/ct is mixed result. L1 SUV is worse. Continue Herceptin/avastin/xgeva. Might revisit Perjeta for L1. Meantime going for rads consult for L1
December 2015 - brain stable. Continue Herceptin, Perjeta, Avastin and xgeva.
Jan 2016: 5 days, 20 grays, Rads to L1 and continue on HAPX. I’m trying to "save" TDM1 for next line. Hope the rads work to quiet L1. Sciatic pain extraordinaire :((
Markers drop post rads.
2/24/16 HAP plus X - markers are down
SCIATIC PAIN DEAL BREAKER.
3/23/16 Laminectomy w/coflex implant L4/5. NO MORE SCIATIC PAIN!!! Healing.
APRIL 2016 - 9 YRS MBC
July 2016 - continue HAP plus Xgeva.
DEC 2016 - PETCT: mets to sternum, lungs, L1 still about the same in size and PET activity. Markers not bad. Not making changes if I don't need to. Herceptin/Perjeta/Avastin/Xgeva
APRIL 2017 10 YEARS MBC
December 2017 - Progression - gonna switch it up
FEB 2018 - Kadcyla 3 cycles ---->progression :(
MAY30th - bronchoscopy, w/foundation1 - her2 enriched
Aug 27, 2018 - start clinical trial ZW25
JAN 2019 - ZW25 seems to be keeping me stable
APRIL 2019 - ONE DOZEN YEARS LIVING METASTATIC
MAY 2019 - progression back on herceptin add xeloda
JUNE 2019 - "6 mos average survival" LMD & CNS new single brain met - one zap during 5 days true beam SBRT to cord met
10/30/19 - stable brain and cord. progression lungs and bones. washing out. applying for ds8201a w nivolumab. hope they take me.
12/27/19 - begin ds8401a w nivolumab. after 2nd cycle nodes melt away. after 3rd cycle chest scan shows Improvement, brain MRI shows improvement, resolved areas & nothing new. switch to plain ENHERTU. after 4th cycle, PETscan shows mostly resolved or improved results. Markers near normal. I'm stunned but grateful.
10/26/20 - June 2021 Tucatinib/xeloda/herceptin - stable ish.
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Old 07-19-2008, 11:50 AM   #16
rentrac
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I've had the same problem ever since starting Tykerb/Xeloda July '07. Superglue now OK'd by oncologists but I find you still have to be very careful. I tend to have 4-6 all the time. I tell the kids who ask that I'm taking Mummies for Dummies and that we start with the fingers when they ask me about my butterflies. The best thing I've found for heels and hands is neosporin, plus super hydrating cream from Bath and Body Works plus wrapping in bread bags or other plastic bags and sleep in the mess. It really helps alot. But meanwhile, the sure do hurt!








__________________
Oct. 2003: Dx age 48, Stage IIIA Ductal Ca. dense dose neoadjuvent AC. BrCa 1&2 -, ER+, PR-, Her2+. 2004: R mastectomy, 3+ nodes, dense doseTaxotere ( allergic), total hysterectomy, radiationx36 . Tamoxifen x6 mo., Arimidex x9 mo. Jan. '06: Multi left metastatic nodes left neck. Stage IV. Taxol, Carboplatin (allergic to both), Herceptin, radiationx27. Herceptin cont'd. 1 mediastinal met in old rad field. April: 2 brain mets - Rcerebellar, Ltemporal lobe. Gammaknife. Stop Herceptin, Start Tykerb. May: CyberKnife-mediastinal node, Zometa restart. July: New RLung mets. Xeloda add. Jan. 2008: CT: Lung mets shrinking. Fatty liver w/increased liver function panel. Feb '08: MRI: brain mets back, 2nd GammaKnife. June: Migraine headaches from cerebellar tumor. Team for WBR - Choose Craniotomy on Cerebellum only. Aug: Crainiotomy successful. Sept: PET -right lung apex clean; left internal mammary artery appears malignant. Herceptin in future. Left mastectomy?
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Old 07-19-2008, 12:28 PM   #17
CindyE
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I have a split right now in my thumb. It's making it hard for me to crochet as it is where I hold the hook. I'm trying a little bag balm on it and it seems to be helping.
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Cindy

L/IDC, 1.2 cm, Stage 1, Her2+, ER+/PR+ at age 48
4/15/2008 Lumpectomy + sentinel node biopsy
Margins neg and Nodes neg (2 tested)
MUGA score 55 on 5/6/2008

Treatment starting 05/08/2008:
Chemo 4 cycles, 3 weeks apart with Taxotere & Cytoxan - Chemo - Done 7/24/2008!
Herceptin for 1 year
Radiation starting in 9/2008
MUGA score 61.9 on 9/04/2008
33 Rads with boost - Done 10/13/2008
MUGA score 58 on 12/01/2008
MUGA score 59 on 3/16/2009
Herceptin for 1 year - Done 4/27/2009
MUGA score 64 on 6/22/2009
All scans - NED 6/24/2009
MRI - NED 11/10/2009
All scans - Still NED 8/25/2011
Still NED 2017!



I am calling this my pink journey
Follow my journey into the pink at my blog here

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Old 08-03-2008, 07:12 AM   #18
TerriC
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I have the weak, thin nails and the splits in the end of my fingers too. I have found that if I use Glove Me Tender from Bath & Body, it prevents those. It is a little on the pricey side, but it worked for me.
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Old 08-03-2008, 08:41 AM   #19
hutchibk
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For my feet, it turns out the best thing I have found so far is Cetaphil Cream in a tub... it works amazing, with socks at night while sleeping. I have no more cracked heels. I use it only 2 nights a week. It does have Petrolatum in it, but at this point I have decided to go with what works... I suppose you could use it on hands and sleep in light cotton gloves a couple of times a week.

When I get the splits in my fingertips (it only happens rarely these days) I just use antibiotic gel and keep em dry with [supposed] water-proof band-aids until they heal over. It has worked well for me when I need it, and I am well invested in the generic band-aid market...

I tried to get the Uria creams as prescribed by my Dermo, but my Prescription Part D plan laughed. They are not covered on any tier of my coverage and the one I was written for was going to cost $280. Oh well. I chose Cetaphil instead.
__________________
Brenda

NOV 2012 - 9 yr anniversary
JULY 2012 - 7 yr anniversary stage IV (of 50...)

Nov'03~ dX stage 2B
Dec'03~
Rt side mastectomy, Her2+, ER/PR+, 10 nodes out, one node positive
Jan'04~
Taxotere/Adria/Cytoxan x 6, NED, no Rads, Tamox. 1 year, Arimadex 3 mo., NED 14 mo.
Sept'05~
micro mets lungs/chest nodes/underarm node, Switched to Aromasin, T/C/H x 7, NED 6 months - Herceptin only
Aug'06~
micro mets chest nodes, & bone spot @ C3 neck, Added Taxol to Herceptin
Feb'07~ Genetic testing, BRCA 1&2 neg

Apr'07~
MRI - two 9mm brain mets & 5 punctates, new left chest met, & small increase of bone spot C3 neck, Stopped Aromasin
May'07~
Started Tykerb/Xeloda, no WBR for now
June'07~
MRI - stable brain mets, no new mets, 9mm spots less enhanced, CA15.3 down 45.5 to 9.3 in 10 wks, Ty/Xel working magic!
Aug'07~
MRI - brain mets shrunk half, NO NEW BRAIN METS!!, TMs stable @ 9.2
Oct'07~
PET/CT & MRI show NED
Apr'08~
scans still show NED in the head, small bone spot on right iliac crest (rear pelvic bone)
Sept'08~
MRI shows activity in brain mets, completed 5 fractions/5 consecutive days of IMRT to zap the pesky buggers
Oct'08~
dropped Xeloda, switched to tri-weekly Herceptin in combo with Tykerb, extend to tri-monthly Zometa infusion
Dec'08~
Brain MRI- 4 spots reduced to punctate size, large spot shrunk by 3mm, CT of torso clear/pelvis spot stable
June'09~
new 3-4mm left cerrebellar spot zapped with IMRT targeted rads
Sept'09~
new 6mm & 1 cm spots in pituitary/optic chiasm area. Rx= 25 days of 3D conformal fractionated targeted IMRT to the tumors.
Oct'09~
25 days of low dose 3D conformal fractionated targeted IMRT to the bone mets spot on rt. iliac crest that have been watching for 2 years. Added daily Aromasin back into treatment regimen.
Apr'10~ Brain MRI clear! But, see new small spot on adrenal gland. Change from Aromasin back to Tamoxifen.
June'10~ Tumor markers (CA15.3) dropped from 37 to 23 after one month on Tamoxifen. Continue to monitor adrenal gland spot. Remain on Tykerb/Herceptin/Tamoxifen.
Nov'10~ Radiate positive mediastinal node that was pressing on recurrent laryngeal nerve, causing paralyzed larynx and a funny voice.
Jan'11~ MRI shows possible activity or perhaps just scar tissue/necrotic increase on 3 previously treated brain spots and a pituitary spot. 5 days of IMRT on 4 spots.
Feb'11~ Enrolled in T-DM1 EAP in Denver, first treatment March 25, 2011.
Mar'11~ Finally started T-DM1 EAP in Denver at Rocky Mountain Cancer Center/Rose on Mar. 25... hallelujah.

"I would rather be anecdotally alive than statistically dead."

Last edited by hutchibk; 08-03-2008 at 08:48 AM.. Reason: spelling
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Old 08-03-2008, 10:00 AM   #20
DanaRT
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Join Date: Dec 2007
Location: Avilla, Indiana
Posts: 261
The skin at my finger tips split wide open. Very painful. Liquid bandaid worked well. It stings intially. I wore gloves to clean house and do dishes.
Now that I am on Herceptin alone I have not had any trouble.
My biggest complaint now is sore hip, knee and ankle joints, it's worse in the evening. It takes a few seconds to become mobile.

Dana
__________________
-Dana-

]
Diagnosed - Nov. 2, 2007 at 45
Lumpectomy - Nov. 13, 2007
Tumor 1.2 cm
Stage 1 Grade 3
ER/PR - Her2 +++ (3.8)
Taxotere/Carboplatin/Herceptin- 6 rounds
Neulasta
Radiation 33 treatments - will be done 6/6/08
Herceptin through 12/08
12/07 MUGA 61%, 4/08 MUGA 60%, 7/08 MUGA 64%
three wonderful daughters, a terrific husband,
Life is Good
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