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Old 11-10-2023, 10:53 AM   #1
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Join Date: Nov 2005
Posts: 524
GATA3 mediates doxorubicin resistance ...

Of late, I've been seeing Gata-3 in pathology report. Gata-3 status is one of the information needed to determine if cells are from the breast or elsewhere and if cells are malignant. Below articles should be discussed with your oncologist if you are Gata-3 positive and considering chemo especially doxorubicin. Incidentally Gata-3 status can be determine via staining.

GATA3 mediates doxorubicin resistance by inhibiting CYB5R2-catalyzed iron reduction in breast cancer cells


Clinicopathological analysis of GATA3-positive breast cancers with special reference to response to neoadjuvant chemotherapy

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