Switch to Fulvestrant and Palbociclib vs No Switch in Advanced Breast Cancer With Rising ESR1 Mutations During Aromatase Inhibitor and Palbociclib Therapy
https://www.thelancet.com/journals/l...555-1/fulltext
Note the "take home message" section and DO's comment. But I think one of the key point is the use of liquid biopsy to change regimen.
https://www.practiceupdate.com/c/142...1&lid=20849614