 |
06-10-2013, 06:08 PM
|
#1
|
|
Senior Member
Join Date: Dec 2012
Location: Attica, IN
Posts: 371
|
Does anyone know about skipping hercept?
My dad had a heart attack and will be having open heart surgery Friday. He takes plavix so if they can keep him stable and he can not have any episodes while in hospital then Friday is triple bypass surgery day.
Anyway, I have herceptin Wednesday and I have side effects from it, and I will be with him Friday thru the weekend. Then my next herceptin is already scheduled for July3rd. I know I have missed 1 other time because I was sick and I think nurse said we just add one on at the end.
Does anyone think missing June12th and just going to my July 3rd herceptin is a big deal. I will call the doctor tomorrow, but I am just curious what others have done.
__________________
myleftlump.wordpress.com - started blogging my
IDC breast cancer
7/2012 diagnosed with multiple solid lesions
7/20/12 biopsy done. ER+ 30 PR -, HER+++,k167 80% Grade 2
9/2012 biopsy on lymph node - showed malignant
9/2012 Pre-adjunctive TCH chemo.
12/6/12 MRI after Pre-adj.
Results: Modest Decrease in size of left breast malignancy As well as the associated satellite lesions and auxiliary Adenopathy compared to prior study. Doctors hoped for better but good response it didn't grow.
12/18/2012 left masectomy with axillary nodes
Size 3.2 CM, Nottingham score 9/9
Grade 3, no evidence of in situ carcinoma
Areas of angiolymphatic are identified
Carcinoma is 0.5 cm from inked deep
Margin of excision
Attached axillary lymph nodes: metastatic
Carcinoma in 6 of 8 nodes.
Size of largest node 1.5 cm
Extracapsular
ER + 73%, PR+2%, HER2+
2/27/13 6 weeks of IMRT radiation finished
2/2013 Started on Tamoxifan 5 years.
8/2013 will take last Herceptin, 17 treatments total every 3 weeks.
BRCA1 & BRAC2 - Negative
August 28, 2013 DIEP flap on the left breast.
February 2014 Nip & Tuck
March 14, 2014 nipple reconstruction and removed port.
August 14, 2014 lump in lymph nodes under arm and above clavicle. Stage IV
August 28, 2014 herceptin And projeta starting and port put back in.
3/18/15 stopped arimidex.
3/18/15 progression....Tdm1
|
|
|
|
06-10-2013, 06:43 PM
|
#2
|
|
Senior Member
Join Date: Sep 2005
Location: Stockton, NJ
Posts: 4,179
|
Re: Does anyone know about skipping hercept?
Go as early as you can to take the skipped dose and redo your schedule.
__________________
Kind regards
Becky
Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia
NED 18 years!
Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
|
|
|
|
|
06-11-2013, 02:58 AM
|
#3
|
|
Senior Member
Join Date: Feb 2009
Posts: 1,526
|
Re: Does anyone know about skipping hercept?
Hi
My understanding is that if you skip a dose by more than 4 weeks you need another loading dose to ensure its effectiveness. Could your Doctor give you anything to deal with the side effects?
Ellie
|
|
|
|
|
06-11-2013, 07:58 AM
|
#4
|
|
Senior Member
Join Date: Dec 2012
Location: Attica, IN
Posts: 371
|
Re: Does anyone know about skipping hercept?
What do you mean by a loading dose to ensure it's effectiveness?? I called today and she rescheduled for Tuesday, June 18th instead of Wednesday the 12th.
__________________
myleftlump.wordpress.com - started blogging my
IDC breast cancer
7/2012 diagnosed with multiple solid lesions
7/20/12 biopsy done. ER+ 30 PR -, HER+++,k167 80% Grade 2
9/2012 biopsy on lymph node - showed malignant
9/2012 Pre-adjunctive TCH chemo.
12/6/12 MRI after Pre-adj.
Results: Modest Decrease in size of left breast malignancy As well as the associated satellite lesions and auxiliary Adenopathy compared to prior study. Doctors hoped for better but good response it didn't grow.
12/18/2012 left masectomy with axillary nodes
Size 3.2 CM, Nottingham score 9/9
Grade 3, no evidence of in situ carcinoma
Areas of angiolymphatic are identified
Carcinoma is 0.5 cm from inked deep
Margin of excision
Attached axillary lymph nodes: metastatic
Carcinoma in 6 of 8 nodes.
Size of largest node 1.5 cm
Extracapsular
ER + 73%, PR+2%, HER2+
2/27/13 6 weeks of IMRT radiation finished
2/2013 Started on Tamoxifan 5 years.
8/2013 will take last Herceptin, 17 treatments total every 3 weeks.
BRCA1 & BRAC2 - Negative
August 28, 2013 DIEP flap on the left breast.
February 2014 Nip & Tuck
March 14, 2014 nipple reconstruction and removed port.
August 14, 2014 lump in lymph nodes under arm and above clavicle. Stage IV
August 28, 2014 herceptin And projeta starting and port put back in.
3/18/15 stopped arimidex.
3/18/15 progression....Tdm1
|
|
|
|
|
06-11-2013, 11:30 AM
|
#5
|
|
Senior Member
Join Date: Mar 2012
Posts: 199
|
Re: Does anyone know about skipping hercept?
4 days wont make a difference Ellie is right, if it is longer (forgot how long) they will have to give you a loading dose, its the same amt that you got when you first started, which is different then the subsequent amts
__________________
diagnosed aug/11
right breast IDC 2.2 cm LVI
neoadjuvant fecx3, tax and her x3
surgery -pCR 0/2 nodes
25 rads
herceptin x18
tamox
prophy bi-msx with TE's oct 15/12
LD flap reconstruction (PM me if you want the details)
zoladex shots monthly until SOFT studies come out
|
|
|
|
|
06-11-2013, 11:40 AM
|
#6
|
|
Senior Member
Join Date: Dec 2012
Location: Attica, IN
Posts: 371
|
Re: Does anyone know about skipping hercept?
My first 6 were with TCH which finished November 27th which the Herceptin was less then because of the chemo drugs. Herceptin Alone started in December, and I assumed it was the 400 mg since I started doing it alone. Geez, I had no idea about the dosage and missing a cycle. I see my ONC next on July 9th, so I will have to write these questions down. The only thing the nurse told me was they based how much they were giving me by my weight.
__________________
myleftlump.wordpress.com - started blogging my
IDC breast cancer
7/2012 diagnosed with multiple solid lesions
7/20/12 biopsy done. ER+ 30 PR -, HER+++,k167 80% Grade 2
9/2012 biopsy on lymph node - showed malignant
9/2012 Pre-adjunctive TCH chemo.
12/6/12 MRI after Pre-adj.
Results: Modest Decrease in size of left breast malignancy As well as the associated satellite lesions and auxiliary Adenopathy compared to prior study. Doctors hoped for better but good response it didn't grow.
12/18/2012 left masectomy with axillary nodes
Size 3.2 CM, Nottingham score 9/9
Grade 3, no evidence of in situ carcinoma
Areas of angiolymphatic are identified
Carcinoma is 0.5 cm from inked deep
Margin of excision
Attached axillary lymph nodes: metastatic
Carcinoma in 6 of 8 nodes.
Size of largest node 1.5 cm
Extracapsular
ER + 73%, PR+2%, HER2+
2/27/13 6 weeks of IMRT radiation finished
2/2013 Started on Tamoxifan 5 years.
8/2013 will take last Herceptin, 17 treatments total every 3 weeks.
BRCA1 & BRAC2 - Negative
August 28, 2013 DIEP flap on the left breast.
February 2014 Nip & Tuck
March 14, 2014 nipple reconstruction and removed port.
August 14, 2014 lump in lymph nodes under arm and above clavicle. Stage IV
August 28, 2014 herceptin And projeta starting and port put back in.
3/18/15 stopped arimidex.
3/18/15 progression....Tdm1
|
|
|
|
|
06-11-2013, 01:27 PM
|
#7
|
|
Senior Member
Join Date: Feb 2009
Posts: 1,526
|
Re: Does anyone know about skipping hercept?
Hi
You're quite right the dose you receive is based on your weight, you have exactly the same amount as I do!! A loading dose like Roz said is a higher dose but again based on your weight. I believe that you can go up to 7 days over the three weeks but after this you need a further loading dose.
Hope this helps
Ellie
|
|
|
|
|
06-21-2013, 02:49 PM
|
#8
|
|
Senior Member
Join Date: Feb 2011
Location: San Diego, CA
Posts: 133
|
Re: Does anyone know about skipping hercept?
I had a few different conflicts that required rescheduling - weddings, etc. Sometimes I received a 2 week dose and sometimes I received a 3 week dose. My onc didn't seem to think it was a big deal.
__________________
11/19/10 Identified swollen lymph node
1/24/11 Mammogram showed microcalcifications - no mass
2/4/11 Diagnosed ER/PR- HER2+++
2/23/11 Began TCH protocol every 21 days 6x
5/23/11 Ultrasound of originally diseased lymph node shows normal
7/25/11 Lymph node dissection - 8 of 14 show disease
7/29/11 Double mastectomy with reconstruction (expanders)
8/29/11 Begin follow up chemo - Adriamycin 4 treatments every 2 weeks and Xeloda. Self inject Nupogen shots
1/6/12 6 weeks of Radiation finished
2/13/12 Last Herceptin/remove port
3/27/12 PET/Brain Scan NED :)
8/15/12 Final reconstruction - hello nipples, good bye expanders
9/14/12 Rejected implant/infection. Implant removed
5/6/13 Latissumis Dorsi surgery left side with expander
PS - my photo was taken 5 days after my double mastectomy surgery and 6 weeks after my TCH was completed
|
|
|
|
Posting Rules
|
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts
HTML code is Off
|
|
|
All times are GMT -7. The time now is 10:02 AM.
|
Linear Mode
