HonCode

Go Back   HER2 Support Group Forums > her2group
Register Gallery FAQ Members List Calendar Search Today's Posts Mark Forums Read

Reply
 
Thread Tools Display Modes
Old 08-22-2021, 08:00 AM   #1
Nguyen
Senior Member
 
Join Date: Nov 2005
Posts: 503
Anyone on Margetuximab/Margenza without chemo?

Hello,

Is anyone here on Margetuximab (Margenza) without chemo?

Thanks.
Nguyen is offline   Reply With Quote
Old 08-23-2021, 06:36 AM   #2
Donna H
Senior Member
 
Join Date: May 2014
Posts: 307
Re: Anyone on Margetuximab/Margenza without chemo?

Is it an immunotherapy?
Donna H is offline   Reply With Quote
Old 08-23-2021, 07:59 AM   #3
Nguyen
Senior Member
 
Join Date: Nov 2005
Posts: 503
Re: Anyone on Margetuximab/Margenza without chemo?

Margetuximab is very similar to trastuzumab and both are sort of indirect immunotherapy. From the immune aspect, Margetuximab is design specifically to attract (more than herceptin) immune cells, particularly in patients that have CD16A-158F variant immune cells. About 80-85% of breast cancer patients have this. Also there are data that it works to some degree in patient with her2 low. It’s only approved together with chemo. I am perplexed about this chemo requirement, since chemo typically suppressed the immune system.
Nguyen is offline   Reply With Quote
Reply

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Forum Jump


All times are GMT -7. The time now is 03:32 AM.


Powered by vBulletin® Version 3.8.7
Copyright ©2000 - 2024, vBulletin Solutions, Inc.
Copyright HER2 Support Group 2007 - 2021
free webpage hit counter