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Old 07-30-2012, 03:09 PM   #1
Deb33
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Curcumin

My Naturopath found an interesting article on the use of Curcumin with HER2 disease. He has always had me take it from a prevention standpoint but this article is pretty interesting.

http://www.greenmedinfo.com/article/...-breast-cancer
__________________
11/19/10 Identified swollen lymph node
1/24/11 Mammogram showed microcalcifications - no mass
2/4/11 Diagnosed ER/PR- HER2+++
2/23/11 Began TCH protocol every 21 days 6x
5/23/11 Ultrasound of originally diseased lymph node shows normal
7/25/11 Lymph node dissection - 8 of 14 show disease
7/29/11 Double mastectomy with reconstruction (expanders)
8/29/11 Begin follow up chemo - Adriamycin 4 treatments every 2 weeks and Xeloda. Self inject Nupogen shots
1/6/12 6 weeks of Radiation finished
2/13/12 Last Herceptin/remove port
3/27/12 PET/Brain Scan NED :)
8/15/12 Final reconstruction - hello nipples, good bye expanders
9/14/12 Rejected implant/infection. Implant removed
5/6/13 Latissumis Dorsi surgery left side with expander

PS - my photo was taken 5 days after my double mastectomy surgery and 6 weeks after my TCH was completed
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Old 07-31-2012, 12:55 AM   #2
LeahM
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Re: Curcumin

Deb,

I find this very interesting and will talk with my Onc. about it today before chemo #2. I am a firm believer in Vit. and Supplement therapies. I have printed out the abstract you posted to show my Onc.

Where do you buy it? I buy all my supplements from Puritan Pride. Puritan.com. Here is a link to there Cucurmin products, so many to choose from! Any advise as to which one to choose?

http://www.puritan.com/curcumin-521?...order=2&Page=1

Thanks
Leah
__________________
39 year old wife, mother of one and nurse.
April 20, 2012: Dx Invasive Ductal Carcinoma
April 25, 2012: ER+(5%), PR-, HER2+++
May 10, 2012: BRCA 1,2 Negative
May 23, 2012: MUGA Scan EF 70%
May 31, 2012: B/L Mastectomy. 2/2 nodes removed and CLEAR!! Power Port placed. 2 Drains. 2 Expanders placed
June 5, 2012: Drains OUT! Ahhhh..
June 12, 2012: Final Pathology Report, .8x.3cm tumor. Micromets to 1 node .35mm under cytokeratin staining. Stage 2A. Onc says "you are lucky to have found this early"
July 10, 2012: Started 6 rounds of TCH with weekly H
Sept 5, 2012: MUGA 65%
Sept 20, 2012: CAT scan of brain clear!
Oct 23, 2012: LAST TC! AMEN! Continue Herceptin every three weeks until July 2013.
Nov 19, 2012: Port out!
Dec 5, 2012: Started radiation
Dec. 10, 2012: MUGA 65%
Dec. 13, 2012: Turned 40. BEST BIRTHDAY EVER!
Jan 23, 2013: Last radiation. Told I am NED. Continue Herceptin every three weeks till July 2013.
Jan 29, 2013: Begin 5 years of Tamoxifen.
Feb 28, 2013: CT Scan with Contrast of lungs. 5mm and 4mm nodules of unknown origin. Rescan in 3 months.
Mar 6, 2013: EF 60%
May 8, 2013: Exanders out, implants implanted...abd. lipo and fat moved up. Girls are looking good!
June 3, 2013: CT Scan with Contrast of lungs. Previous nodules gone. New nodules (2mm and 3mm) found. Rescan in 3 months. So sorry I opened this can of worms...
June 11, 2013: EF 60%
June 25, 2013: Last Herceptin. wow...
Aug 20, 2013: Tumor markers within normal limits. Xray to sore left ribs shows no disease or fractures.
Sept 9, 2013: CT of lungs shows no disease. Closing this can of worms and moving on.
Nov 20, 2013: Tumor markers within normal limits. Severe Vit D deficiency, started on prescription Vit. D. Blaming chemo for this.
Feb 2014: Tumor markers within normal limits.
May 2014: Tumor markers within normal limits. Graduated to twice yearly onc appts.
Oct 2014: Tumor markers within normal limits.
May 2015: Tumor markers WNL. Bone density scan fine. Bone scan and xray of ribs shows "something" 4th right rib. Could be healed fracture but if it is healed why does it hurt?
Nov 2015: Tumor markers WNL. Follow up bone scan clear.
Feb 2016: Syncope! WTF? Dizzy too. Brain scan clear, ECHO EF 60%, Halter Monitor shows heart is fine. Viral? I will never know.
June 2016: Tumor markers WNL.
Oct 2016: Stabbing pain right eye. Long story short, trigeminal neuralgia.
Nov 2016 Brain MRI clear.
Jan 2017: Tumor markers WNL, still getting weird pain right rib area, and sometimes right upper chest. Xray x2, Bone Scan, Breast MRI all clear. Scar tissue? Rads. I may never know.
www.onmywaytosurvivorhood.blogspot.com
www.thechemobag.com
www.facebook.com/thechemobag

Last edited by LeahM; 07-31-2012 at 12:56 AM.. Reason: forgot a link
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Old 07-31-2012, 04:59 AM   #3
Becky
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Re: Curcumin

I also take curcumin daily. I take one 500 mg capsule based on the whole foods study that women from India tend to get less cancers overall and they are figure is curry. A serving of chicken curry has about 200mg of curcumin. Maybe that is so little it doesn't matter. I have been taking this many years and in a couple of weeks I will be an 8 year survivor so who knows.
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Kind regards

Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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Old 07-31-2012, 09:34 AM   #4
Ellie F
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Re: Curcumin

Bharat Agarwaal from MD Anderson has long championed the merits of curcumin referring to its use when he was a child in India. I was persuaded by the fact that bc is 5 times less common in India where the environmental pollution is 5 times greater than in the West!
Ellie
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Old 07-31-2012, 01:37 PM   #5
Mandamoo
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Re: Curcumin

Does anyone know what a therapeutic dose is in supplement form? I have added raw turmeric to my juices - apparently pepper in conjunction activates it more too. The supplements that I have seen use unusual units of measurement and are difficult to compare. Have any studies been done using the supplements rather than food?
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40 year old Mum to three gorgeous kids - son 5 and daughters 8 and 11
Wife to my wonderfully supportive husband of 17 years!
22 February 2011 - Diagnosed Early Breast Cancer IDBC Stage2b (ER/PR -ve, Her2+ve +++) - 38 years old
(L) skin sparing mastectomy with tissue expander, axilla clearance (2/14 affected) clear margins.
Fec*3, Taxotere and herceptin*2 - stopped due to secondary diagnosis

June 24 2011 Stage IV - Skin met, axilla node, multiple lung lesions

Bolero3 trial - Navelbine, Hereptin weekly, daily Everolimus/Placebo
February 2012 - July 2012 Tykerb and Xeloda - skin mets resolved, Lungs initially dramatically reduced but growing again
August 2012 (turn 40!) tykerb and herceptin (denied compassionate use of TDM1) while holidaying in Italy!
September 2012 - January 2013 TDM1 as part of the Th3resa trial - lymph nodes resolved, lungs slowly progressing.
January 2013 - herceptin, carboplatin and Perjeta (compassionate access)
April 2013 - Some progression in lungs and lymph nodes - Abraxane, Herceptin and Perjeta
July 2013 - mixed response - dramatic reduction of most lung disease, progression of smaller lung nodules and cervical and hilar nodes - ? Add avastin.
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Old 07-31-2012, 02:16 PM   #6
Ellie F
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Re: Curcumin

Hi Amanda
Can't just find the research at the minute but curcumin which is the active part of turmeric was taken at quite large doses in supplement form (if I remember correctly about 8mgs plus daily) without toxicity. Will try to find the article tomorrow. I take an organic supplement that also contains black pepper. As you say this is reputed to increase its absorption through the gut.i also try to take it with a little oil as this also is supposed to make it more bio-available.
Just wanted to add a cautionary note in that curcumin can impact on platelets and reduce their number.
Hope this helps
Ellie
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Old 07-31-2012, 06:54 PM   #7
rhondalea
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Re: Curcumin

I wish I could figure out whether the curcumin with Bioperine (Sabinsa C3 Complex) or liposomal curcumin (Meriva*) is better absorbed. I'm currently taking the C3 Complex (500 mg 3x/day), but when I run out, I may switch to the liposomal formulation. I just haven't done enough research to convince myself that one is better than the other. (Note: I'm not taking curcumin for cancer. It turns out that curcumin, like tobacco, is a mild MAOA-I. Together with nicotine lozenges, it is helping me to give up cigarettes.)

This is the pancreatic cancer trial that used 8 g/day:

http://clincancerres.aacrjournals.or.../4491.abstract

There's more information on the various trials at the MSKCC website:

http://www.mskcc.org/cancer-care/herb/turmeric

And this lady has been been keeping her myeloma at bay for quite some time with curcumin:

http://margaret.healthblogs.org/

Her site has a ton of information, all in one place. I have it on my list for reading, but I'm not quite there yet.

Edited to add: *Meriva is not liposomal curcumin. It is curcumin phytosome, which allegedly has even better absorption.
__________________

2/6/09 Core needle biopsy: negative; Mammos through 2010: no change
3/30/11 Pea-sized lump in left breast at site of prior biopsy; mammo negative, sonogram not so much
4/14/11 Core needle biopsy: negative for cancer
5/18/11 Excisional biopsy 1.2 cm tumor, LVI, positive margin; ER+60%,PR+20%,HER2/CEP17 5
6/15/11 BMX: Left DCIS & LH; Right ADH; SNB: 2/3 nodes: 1.4 cm and 1 mm; ALND L1&2: 0/10; Stage IIa, Grade 3
7/14/11 CT/Bone scans NED; MUGA 66%
7/19/11 Biweekly dd AC w/Neulasta; done 8/30/11
9/13/11 Transfusion (Hemoglobin 8.6); MUGA 64%
9/20/11 Start Taxol + Herceptin; Taxol done 12/6/2011; continue Herceptin until 9/4/2012
12/27/11 Radiation - 6 weeks; 2/27/2012 - DONE! Yayyyy!
2/29/12 Start Tamoxifen 20 mg/day; continue until 2/28/17
5/16/12 Start five-years Metformin trial
6/19/12 MUGA 61%
8/21/12 Brain MRI NED (head still hurts, brain still fogged)
9/4/12 Herceptin done!
9/6/12 Port out!
7/11/13 Aricept 5mg for cognitive impairment; increased to 10mg as of 8/23/13; back to 5mg 12/2013
5/2014 Add Namenda 7mg
9/2014 Stop Aricept and Namenda; Neuropsychological evaluation
10/24/14 Start cognitive rehabilitation therapy
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Old 08-01-2012, 03:31 AM   #8
pibikay
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Re: Curcumin

It is a good food supplement and in Indian Aurveda it is used as an antiseptic and also to cure sores,Hema has natural curcmuin as a powder with her buter or mil or fresh pickled with her bread
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huband of Hema
Metstatic Breast Cancer Stage 4
Left breast cauliflower 25x20cm
ossousmetstatis in vertbrae secondaries L4=L5secondary
nodules in both liver lobes secondary
Diagnosed 10th March 2010
ER/PR-ve
Her 2 neu +++
Taxotrne Zylotec started 16th March
Herceptin added 5th April.9th Herceptin over on 20th Sep '10.Started on Tykerb and Xeloda on 22nd Oct2010TYKERB 4 TAB A DAY XELODA 4 TAB A DAY ONE WEEK ON ONE WEEK OFFZoletrust infusion every 4 months.Lesion in Brain 3D CRT Radiation started on 1st Feb'12 for 20 days ,5 days a week for 4 weeks.Devloped a small lump in breast.Xeloda stopped from 11th April '12.On Taxol.After 3 cycles of Taxol Taxol stopped.Back to Xeloda regime from 3rd July
Herceptin started again on 27th Dec 2012.Xeloda stopped Navelbin added on 7th February 2013.Now on Tykerb Herceptin and Navelbin
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Old 08-06-2012, 12:52 PM   #9
sdstarfish
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Re: Curcumin

I was glad to see this discussion, because turmeric/curcumin is a rock star in the world of herbal remedies
Curcumin is not only a great in promoting cancer prevention; it has also been scientifically shown to shrink tumors and to decrease inflammation due to lymphedema and other injuries/illnesses. If you need some inspiration for cooking with turmeric, here are some easy recipes containing turmeric.


Lisa
www.pinkkitchen.info
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Old 08-12-2012, 06:11 AM   #10
LeahM
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Re: Curcumin

Took this abstract and showed it to my (Indian) onc. He says it can't hurt and asked if I had begun taking it. I said no, I wanted to talk to him first he said (again) it can't hurt. But for what he understood it would be more beneficial to take after I am done TC and just on the H. So I asked if I should wait till the chemo portion of my treatment was over and he said wouldn't hurt to start taking it now. So I am. 500mg day but I will research larger doses.

Deb, you mentioned in another thread that you didn't take it the two days before and after chemo based on your oncs. recommendation. My onc didn't say anything about that. Was there a reason why you stopped it during that time?

Leah
__________________
39 year old wife, mother of one and nurse.
April 20, 2012: Dx Invasive Ductal Carcinoma
April 25, 2012: ER+(5%), PR-, HER2+++
May 10, 2012: BRCA 1,2 Negative
May 23, 2012: MUGA Scan EF 70%
May 31, 2012: B/L Mastectomy. 2/2 nodes removed and CLEAR!! Power Port placed. 2 Drains. 2 Expanders placed
June 5, 2012: Drains OUT! Ahhhh..
June 12, 2012: Final Pathology Report, .8x.3cm tumor. Micromets to 1 node .35mm under cytokeratin staining. Stage 2A. Onc says "you are lucky to have found this early"
July 10, 2012: Started 6 rounds of TCH with weekly H
Sept 5, 2012: MUGA 65%
Sept 20, 2012: CAT scan of brain clear!
Oct 23, 2012: LAST TC! AMEN! Continue Herceptin every three weeks until July 2013.
Nov 19, 2012: Port out!
Dec 5, 2012: Started radiation
Dec. 10, 2012: MUGA 65%
Dec. 13, 2012: Turned 40. BEST BIRTHDAY EVER!
Jan 23, 2013: Last radiation. Told I am NED. Continue Herceptin every three weeks till July 2013.
Jan 29, 2013: Begin 5 years of Tamoxifen.
Feb 28, 2013: CT Scan with Contrast of lungs. 5mm and 4mm nodules of unknown origin. Rescan in 3 months.
Mar 6, 2013: EF 60%
May 8, 2013: Exanders out, implants implanted...abd. lipo and fat moved up. Girls are looking good!
June 3, 2013: CT Scan with Contrast of lungs. Previous nodules gone. New nodules (2mm and 3mm) found. Rescan in 3 months. So sorry I opened this can of worms...
June 11, 2013: EF 60%
June 25, 2013: Last Herceptin. wow...
Aug 20, 2013: Tumor markers within normal limits. Xray to sore left ribs shows no disease or fractures.
Sept 9, 2013: CT of lungs shows no disease. Closing this can of worms and moving on.
Nov 20, 2013: Tumor markers within normal limits. Severe Vit D deficiency, started on prescription Vit. D. Blaming chemo for this.
Feb 2014: Tumor markers within normal limits.
May 2014: Tumor markers within normal limits. Graduated to twice yearly onc appts.
Oct 2014: Tumor markers within normal limits.
May 2015: Tumor markers WNL. Bone density scan fine. Bone scan and xray of ribs shows "something" 4th right rib. Could be healed fracture but if it is healed why does it hurt?
Nov 2015: Tumor markers WNL. Follow up bone scan clear.
Feb 2016: Syncope! WTF? Dizzy too. Brain scan clear, ECHO EF 60%, Halter Monitor shows heart is fine. Viral? I will never know.
June 2016: Tumor markers WNL.
Oct 2016: Stabbing pain right eye. Long story short, trigeminal neuralgia.
Nov 2016 Brain MRI clear.
Jan 2017: Tumor markers WNL, still getting weird pain right rib area, and sometimes right upper chest. Xray x2, Bone Scan, Breast MRI all clear. Scar tissue? Rads. I may never know.
www.onmywaytosurvivorhood.blogspot.com
www.thechemobag.com
www.facebook.com/thechemobag
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Old 08-12-2012, 06:14 PM   #11
ElaineM
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Wink Re: Curcumin

I take curcumin in supplement form and add tumeric to alot of things I cook. It is good added to stir fried veggies and plain Asian noodles along with ginger and garlic with a tiny amount of shoyu.
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12 years and counting
http://her2support.org/vbulletin/showthread.php?t=48247
Lucky 13 !! I hope so !!!!!!
http://her2support.org/vbulletin/showthread.php?t=52807
14 Year Survivor
http://her2support.org/vbulletin/showthread.php?t=57053
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Old 08-13-2012, 07:07 AM   #12
Deb33
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Re: Curcumin

I was on a bunch of supplements and my Onc was fine with everything as long as I did nothing 3 days before and 3 days after. Seemed to be his point of view. He did take note of some of the things I discovered along the way but I'm not sure he is recommending them to others.
- B6/12 shots twice a week during Xeloda - never had an issue with feet or hands.
- DRibose powder daily during Herceptin - muga score went from 70% to 75%.
- Weekly Glutathione IV's during Carbo - limited neuropathy side effects.
- L Glutamine daily after 3rd chemo - stopped muscle cramping.
- Weekly acupuncture - removed nausea

And on another vain note - my hair came in thick, full and a little wavy unlike the majority who have kinky, damaged hair growth initially. I have been told that those of us who take additional nutrition have better luck with a normal hair shaft.
__________________
11/19/10 Identified swollen lymph node
1/24/11 Mammogram showed microcalcifications - no mass
2/4/11 Diagnosed ER/PR- HER2+++
2/23/11 Began TCH protocol every 21 days 6x
5/23/11 Ultrasound of originally diseased lymph node shows normal
7/25/11 Lymph node dissection - 8 of 14 show disease
7/29/11 Double mastectomy with reconstruction (expanders)
8/29/11 Begin follow up chemo - Adriamycin 4 treatments every 2 weeks and Xeloda. Self inject Nupogen shots
1/6/12 6 weeks of Radiation finished
2/13/12 Last Herceptin/remove port
3/27/12 PET/Brain Scan NED :)
8/15/12 Final reconstruction - hello nipples, good bye expanders
9/14/12 Rejected implant/infection. Implant removed
5/6/13 Latissumis Dorsi surgery left side with expander

PS - my photo was taken 5 days after my double mastectomy surgery and 6 weeks after my TCH was completed
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Old 08-13-2012, 11:22 AM   #13
LeahM
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Re: Curcumin

Interesting info Deb. I am taking B6 now, in addition to the B Complex I have been taking for years. Having minimal numbness in my left hand, that I think is because of past nerve problems I've had (and had surgery for Jan 2012)
I am going to look up Glutathione.

My hair has always been kinky and thin...hoping it grows back more like my wig....which, BTW, I never wear...too hot. Too itchy.
__________________
39 year old wife, mother of one and nurse.
April 20, 2012: Dx Invasive Ductal Carcinoma
April 25, 2012: ER+(5%), PR-, HER2+++
May 10, 2012: BRCA 1,2 Negative
May 23, 2012: MUGA Scan EF 70%
May 31, 2012: B/L Mastectomy. 2/2 nodes removed and CLEAR!! Power Port placed. 2 Drains. 2 Expanders placed
June 5, 2012: Drains OUT! Ahhhh..
June 12, 2012: Final Pathology Report, .8x.3cm tumor. Micromets to 1 node .35mm under cytokeratin staining. Stage 2A. Onc says "you are lucky to have found this early"
July 10, 2012: Started 6 rounds of TCH with weekly H
Sept 5, 2012: MUGA 65%
Sept 20, 2012: CAT scan of brain clear!
Oct 23, 2012: LAST TC! AMEN! Continue Herceptin every three weeks until July 2013.
Nov 19, 2012: Port out!
Dec 5, 2012: Started radiation
Dec. 10, 2012: MUGA 65%
Dec. 13, 2012: Turned 40. BEST BIRTHDAY EVER!
Jan 23, 2013: Last radiation. Told I am NED. Continue Herceptin every three weeks till July 2013.
Jan 29, 2013: Begin 5 years of Tamoxifen.
Feb 28, 2013: CT Scan with Contrast of lungs. 5mm and 4mm nodules of unknown origin. Rescan in 3 months.
Mar 6, 2013: EF 60%
May 8, 2013: Exanders out, implants implanted...abd. lipo and fat moved up. Girls are looking good!
June 3, 2013: CT Scan with Contrast of lungs. Previous nodules gone. New nodules (2mm and 3mm) found. Rescan in 3 months. So sorry I opened this can of worms...
June 11, 2013: EF 60%
June 25, 2013: Last Herceptin. wow...
Aug 20, 2013: Tumor markers within normal limits. Xray to sore left ribs shows no disease or fractures.
Sept 9, 2013: CT of lungs shows no disease. Closing this can of worms and moving on.
Nov 20, 2013: Tumor markers within normal limits. Severe Vit D deficiency, started on prescription Vit. D. Blaming chemo for this.
Feb 2014: Tumor markers within normal limits.
May 2014: Tumor markers within normal limits. Graduated to twice yearly onc appts.
Oct 2014: Tumor markers within normal limits.
May 2015: Tumor markers WNL. Bone density scan fine. Bone scan and xray of ribs shows "something" 4th right rib. Could be healed fracture but if it is healed why does it hurt?
Nov 2015: Tumor markers WNL. Follow up bone scan clear.
Feb 2016: Syncope! WTF? Dizzy too. Brain scan clear, ECHO EF 60%, Halter Monitor shows heart is fine. Viral? I will never know.
June 2016: Tumor markers WNL.
Oct 2016: Stabbing pain right eye. Long story short, trigeminal neuralgia.
Nov 2016 Brain MRI clear.
Jan 2017: Tumor markers WNL, still getting weird pain right rib area, and sometimes right upper chest. Xray x2, Bone Scan, Breast MRI all clear. Scar tissue? Rads. I may never know.
www.onmywaytosurvivorhood.blogspot.com
www.thechemobag.com
www.facebook.com/thechemobag
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Old 08-13-2012, 01:26 PM   #14
Alyce
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Re: Curcumin

HI Deb- I just erased my whole message!
In short- My oncologist is very much against supplements. I have been taking Curcumin for last few months. Are you taking Femara? I had my surgery, chemo, radiation, herceptin in 2008.
Since - no have high cholesterol even though we have a really good diet, no processed food, very little meat, fish,mostly veggies, fruit, beans.
Also- I have never had a weight problem until about 2 years ago. Maybe the Femara?
I would like to know more about what other supplements you have found helpful.
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Old 08-14-2012, 08:26 AM   #15
TanyaRD
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Re: Curcumin

Just wanted to chime in on Leah's question as to why curcumin might be avoided a few days before and after chemo. This is likely because curcumin is a strong antioxidant. In some studies antioxidants have been shown to decrease the effectiveness of certain chemotherapy agents. Other studies have shown the opposite or no effect. The onc I work for perfers to err on the side of caution and we recommend avoidance for 2-3 days before and after treatment but fully support its use after treatment is complete.
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Old 08-16-2012, 09:13 AM   #16
JillaryJill
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Re: Curcumin

Question. I have high blood pressure, but controlled by daily medicine. Can I take Curcumin with high blood pressure meds? Any help would be greatly appreciated.
Thank you!
__________________
DX November 2010
Brain MRI, CT of lung, liver, bone, all clear
Double Mastectomy w/expanders December 1, 2010
ER- PR- Her2+++, grade 3, 12 positive nodes out of 15
Stage IIIc
Started TCH/Chemo December 31, 2010
6 rounds TCH
Herceptin every 3 weeks for a year
33 rounds of TomoTube radiation, to chest wall, neck, skin and lymph area
September, 2011, MRI to lower spine, hips, DX bulging disk, L4 & L5, pain not from cancer
Expanders removed, implants in Dec 1, 2011
Finished Herceptin, December 21, 2011
August 2012, CT of chest and abdomen, all ok
Enrolled in MC1136 Phase I Peptide Vaccine Trial at Mayo Clinic, Rochester, Minnesota
March 2013, First Vaccine
April 2013, 2nd Vaccine
May 2013, 3rd Vaccine
June 2013, 4th Vaccine
July 2013, 5th Vaccine
August 2013, 6th Vaccine Done!
September 2013, Mayo visit, Echo results 68, vaccine did not effect my heart! Blood work normal.
January 31, 2013, Mayo visit, Echo normal
February 23, 2014, Numb lips on right side, Brain MRI, normal!
June, 2015, Finished the trial at Mayo Clinic. Feels good!
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Old 08-16-2012, 07:07 PM   #17
rhondalea
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Re: Curcumin

In theory (animal studies--dogs, actually), curcumin caused transient hypotension.

In practice, it does not:

http://www.ncbi.nlm.nih.gov/pubmed/1...?dopt=Abstract

I went through the entire Natural Standard monograph looking for a problem with blood pressure, and that was the sum total. There was nothing at all at the Natural Medicines Comprehensive Database. If you'll post the specific drug you're taking, I'll check for interactions. Or, you can go here and check it yourself:

http://www.doctoroz.com/videos/drug-interaction-checker

You'll want look for "turmeric" (because "curcumin" isn't listed).

As soon as I have two functioning neurons to rub together, I'll post a link to a downloadable copy of the full curcumin monograph for anyone who wants to read it.
__________________

2/6/09 Core needle biopsy: negative; Mammos through 2010: no change
3/30/11 Pea-sized lump in left breast at site of prior biopsy; mammo negative, sonogram not so much
4/14/11 Core needle biopsy: negative for cancer
5/18/11 Excisional biopsy 1.2 cm tumor, LVI, positive margin; ER+60%,PR+20%,HER2/CEP17 5
6/15/11 BMX: Left DCIS & LH; Right ADH; SNB: 2/3 nodes: 1.4 cm and 1 mm; ALND L1&2: 0/10; Stage IIa, Grade 3
7/14/11 CT/Bone scans NED; MUGA 66%
7/19/11 Biweekly dd AC w/Neulasta; done 8/30/11
9/13/11 Transfusion (Hemoglobin 8.6); MUGA 64%
9/20/11 Start Taxol + Herceptin; Taxol done 12/6/2011; continue Herceptin until 9/4/2012
12/27/11 Radiation - 6 weeks; 2/27/2012 - DONE! Yayyyy!
2/29/12 Start Tamoxifen 20 mg/day; continue until 2/28/17
5/16/12 Start five-years Metformin trial
6/19/12 MUGA 61%
8/21/12 Brain MRI NED (head still hurts, brain still fogged)
9/4/12 Herceptin done!
9/6/12 Port out!
7/11/13 Aricept 5mg for cognitive impairment; increased to 10mg as of 8/23/13; back to 5mg 12/2013
5/2014 Add Namenda 7mg
9/2014 Stop Aricept and Namenda; Neuropsychological evaluation
10/24/14 Start cognitive rehabilitation therapy
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Old 08-24-2012, 11:37 AM   #18
sdstarfish
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Join Date: Nov 2010
Posts: 163
Re: Curcumin

I have a question for any of you with Indian heritage - are there desserts made with curcumin or turmeric?

Lisa
www.pinkkitchen.info
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Old 08-24-2012, 12:15 PM   #19
rhondalea
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Join Date: Jun 2011
Location: Somerset, NJ
Posts: 487
Re: Curcumin

I'm not Indian, but having experienced the turmeric and milk combo that soothes a variety of ills, I think that rice or tapioca pudding with turmeric would be very yummy. I'm also guessing that turmeric would add a lovely note to custard-based desserts.
__________________

2/6/09 Core needle biopsy: negative; Mammos through 2010: no change
3/30/11 Pea-sized lump in left breast at site of prior biopsy; mammo negative, sonogram not so much
4/14/11 Core needle biopsy: negative for cancer
5/18/11 Excisional biopsy 1.2 cm tumor, LVI, positive margin; ER+60%,PR+20%,HER2/CEP17 5
6/15/11 BMX: Left DCIS & LH; Right ADH; SNB: 2/3 nodes: 1.4 cm and 1 mm; ALND L1&2: 0/10; Stage IIa, Grade 3
7/14/11 CT/Bone scans NED; MUGA 66%
7/19/11 Biweekly dd AC w/Neulasta; done 8/30/11
9/13/11 Transfusion (Hemoglobin 8.6); MUGA 64%
9/20/11 Start Taxol + Herceptin; Taxol done 12/6/2011; continue Herceptin until 9/4/2012
12/27/11 Radiation - 6 weeks; 2/27/2012 - DONE! Yayyyy!
2/29/12 Start Tamoxifen 20 mg/day; continue until 2/28/17
5/16/12 Start five-years Metformin trial
6/19/12 MUGA 61%
8/21/12 Brain MRI NED (head still hurts, brain still fogged)
9/4/12 Herceptin done!
9/6/12 Port out!
7/11/13 Aricept 5mg for cognitive impairment; increased to 10mg as of 8/23/13; back to 5mg 12/2013
5/2014 Add Namenda 7mg
9/2014 Stop Aricept and Namenda; Neuropsychological evaluation
10/24/14 Start cognitive rehabilitation therapy
rhondalea is offline   Reply With Quote
Old 08-24-2012, 01:01 PM   #20
Alyce
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Join Date: Mar 2008
Location: Illinois
Posts: 25
Re: Curcumin

Hi Rhondalea-
Just read your note and am wondering what Trial you are in? I havn't heard about Metformin. I am taking Femara and am wondering what will happen when I reach the 5 year point. Maybe there will be some sort of vaccine???
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