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Re: Experiences with Navelbine
Hi Joyce,
The first time I recurred I did Navelbine/Herceptin. The side affects for this combo is generally well tolerated by most. My worse problem was constipation...it was pretty bad. But found a fix for that. It was pretty hard on my counts so I had to do the Neupogen shots. I did feel a bit nauseated the first 3 or 4 days after infusion, but it never was so bad that I actually got sick or couldn't eat. I just made sure I took my nausea meds to be on the safe side. Other then that I still had a pretty good appetite. It didn't ruin the taste of my food like my first go around with "TCH". My hair did thin some, but not too bad. I did have some jaw pain at times which I read can be a rare side affect...but other then that it really was an easy chemo.
This combo has a good synergy together. There are so many women that have had such great responses with Navelbine/Herceptin. Some that are NED and have remained NED with N/H. (And yes...it is possible that you can actually enjoy life...so make some plans and go have a good time.) 
Chelee
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DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
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Hybrid Mode
