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07-26-2009, 07:21 PM
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#1
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Senior Member
Join Date: Dec 2008
Location: Merritt Island, FL
Posts: 53
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Complete response
I am interested in who else has received that news after surgery path resport -- what was your long term outcome as the result of that news??? Just curious about how wonderful that news really is in terms of long term outcome. thanks
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PATTY
FOUND MY TUMOR IN 11/08 AFTER CLEAR MAMMOGRAM ON 5/31/08
DX 12/09/2008 STAGE II
CHANGED TO STAGE IIIA AFTER MRI
SURGURY FOR TWO PET SCAN NODES IN CHEST NEGATIVE (DEC08)
AC (4 COMPLETE MAR09)
TAXOL HERCEPTIN (12 TREATMENTS COMPLETE IN JUN09 )
SURGERY IN JUN09 - COMPLETE RESPONSE (BOTH BREASTS NEG AND 9/9 LYMPH NODES NEG) NED
HERCEPTIN RESTARTED IN JUL09 WEEKLY UNTIL JUL10
PET SCAN - NEGATIVE DEC11 AND AUG09
BRAC - NEGATIVE SEP09
28 RADS COMPLETE SEP09
BONE SCAN - NEGATIVE MAR10
PET SCAN - NEGATIVE DEC11
PET SCAN - SARCOIDOSIS OCT11 thought cancer was back thank The Lord it is not they think!!!!!!
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07-27-2009, 03:47 PM
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#2
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Senior Member
Join Date: Sep 2005
Location: Naples FL
Posts: 1,744
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maybe remission??? am not familiar with that phrase, "complete response"
__________________
 Suzan W.
age 54 at diagnosis
5/05 suspicious mammogram-left breast
5/05 biopsy-invasive lobular carcinoma with LCIS,8mm tumor,stage 1 grade 2, ER+ PR+ Her2+++
6/14/05 bilateral mastectomy, node neg. all scans neg.
Oncotype DX-high risk
8/05-10/05 4 rounds A/C
10/05 -10/06 1 yr. herceptin
arimidex-5 years
2/14/08 started daily self administered injections..FORTEO for severe osteoporosis
7/28/09 BRCA 1 negative BRCA2 POSITIVE
8/17/09 prophylactic salpingo-oophorectomy
10/15/10 last FORTEOinjection
RECLAST infusion(ostoeporosis)
6/14/10 5 year cancerversary!
8/2010-18%increase in bone density!
no further treatments
Oncologist says, "Go do the Happy Dance"
I say,"What a long strange trip its been"
'One day at a time'
6-14-2015. 10 YEAR CANCERVERSARY!
7-16 to 9-16. Extensive (and expensive) dental work done to save teeth. Damage from osteoporosis and chemo and long term bisphosphonate use
6-14-16. 11 YEAR CANCERVERSARY!!
7-20-16 Prolia injection for severe osteoporosis
2 days later, massive hive outbreak. This led to an eventual dx of Chronic Ideopathic Urticaria, an auto-immune disease from HELL.
6-14-17 12 YEAR CANCERVERSARY!!
still suffering from CIU. 4 hospitilizations in the past year
as of today, 10-31-17 in remission from CIU and still, CANCER FREE!!!
6-14-18 13 YEAR CANCERVERSARY!! NED!!
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07-27-2009, 05:09 PM
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#3
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Senior Member
Join Date: Nov 2004
Location: Misty woods of WA State
Posts: 4,128
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In my cancer path "complete response" was the term used when I became stageIV. What that meant was after a course of treatment that I would have no more evidence of disease and have no more need for chemo.
Perhaps the term could be used for earlier stage cases after all the treatment is finished and the labs and scans cannot detect any sign of the disease. Never heard that referring to surgery alone.
Good luck and welcome to this online community!
__________________
"When I hear music, I fear no danger. I am invulnerable. I see no foe. I am related to the earliest times, and to the latest." H.D. Thoreau
Live in the moment.
MY STORY SO FAR ~~~~
Found suspicious lump 9/2000
Lumpectomy, then node dissection and port placement
Stage IIB, 8 pos nodes of 18, Grade 3, ER & PR -
Adriamycin 12 weekly, taxotere 4 rounds
36 rads - very little burning
3 mos after rads liver full of tumors, Stage IV Jan 2002, one spot on sternum
Weekly Taxol, Navelbine, Herceptin for 27 rounds to NED!
2003 & 2004 no active disease - 3 weekly Herceptin + Zometa
Jan 2005 two mets to brain - Gamma Knife on Jan 18
All clear until treated cerebellum spot showing activity on Jan 2006 brain MRI & brain PET
Brain surgery on Feb 9, 2006 - no cancer, 100% radiation necrosis - tumor was still dying
Continue as NED while on Herceptin & quarterly Zometa
Fall-2006 - off Zometa - watching one small brain spot (scar?)
2007 - spot/scar in brain stable - finished anticoagulation therapy for clot along my port-a-catheter - 3 angioplasties to unblock vena cava
2008 - Brain and body still NED! Port removed and scans in Dec.
Dec 2008 - stop Herceptin - Vaccine Trial at U of W begun in Oct. of 2011
STILL NED everywhere in Feb 2014 - on wing & prayer
7/14 - Started twice yearly Zometa for my bones
Jan. 2015 checkup still shows NED
2015 Neuropathy in feet - otherwise all OK - still NED.
Same news for 2016 and all of 2017.
Nov of 2017 - had small skin cancer removed from my face. Will have Zometa end of Jan. 2018.
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07-28-2009, 08:50 AM
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#4
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Senior Member
Join Date: Feb 2008
Location: Bayarea,CA
Posts: 679
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Hi Patty,
There are a couple of studies that do show that pCR (pathalogical complete response) is relavent in terms of long term disease free survivial. Especially having clean nodes at the time of surgery.
I had hoped for pCR but had a shrinkage from 6.5 cm to 2.5 cm and all lymph nodes clean - So I am optimistic.
Keep us posted. I think you may be the first here with complete response...not sure..
hugs,
shobha
__________________
DX: 06-30-2007 - left breast -stage IIIB, Her2/Neu 3+++, ER weakly positive, PR-
Taxol+herceptin weekly for 3 months
FEC+herceptin every 3 weeks for 3 months
BRCA 1 and 2 - Negative
Jan 2008 - Bilateral mastectomy, prophylactic Rt. side.
Radiation for 5 weeks
Completed my yr of herceptin on 07-14-2008
Brain MRI - 3/2/09 Clean
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07-28-2009, 05:00 PM
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#5
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Senior Member
Join Date: Aug 2008
Location: San Francisco
Posts: 260
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I was told my breast tumor had a "complete response" to treatment. It went away all on its on after treatment with Taxotere, Cytoxan and Herceptin. I never had surgery.
Still battling with mets elsewhere but they're days are numbered. We think the scans are just showing healing and scar tissue now but its hard to be sure.
Complete response can and does happen!
__________________
4/17/08: Dx Stage IV at age 30 - extensive mets to liver, lungs, and bones. Er/Pr-, Her2+++
April 08-Aug 08:Taxotere, Cytoxan, Herceptin, Zometa - complete response!
Sept 08-Dec 08: Herceptin +Zometa for maintenance.
Jan 09-April 09: Brain mets. Add Tykerb. Watch and wait.
April 09: Gamma Knife 10 brain mets, add Xeloda.
Sept 09: Gamma Knife to 1 brain met.
Nov 09- April 10: Lung progression, add Gemzar to Herceptin, Zometa.
May 10- Sept 10: HER2 Vaccine Trial
Sept 10: Add Tykerb for more brain mets.
Oct 10: Gamma Knife to 7 brain mets.
Dec 10: Switch from Zometa to Denosumab.
Jan 11: Gamma Knife to 3 brain mets.
March 11: Gemzar/Herceptin for lung/bone progression.
April 11: More brain mets - Intrathecal Herceptin
June 11: Ixempra/Herceptin for lung, soft tissue progression.
Aug 11: Gamma Knife
Sep 11: Abraxane/Herceptin
Future: NED
Send me a PM if you'd like to follow my journey on Caringbridge.
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07-29-2009, 05:37 AM
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#6
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Member
Join Date: Dec 2007
Posts: 12
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Re: Complete response
Hello,
I also had cpr after neo-adjuvant chemo. It is a term used when you have chemo before surgery and then when they do remove and examine the tissue where cancer was initially, if they find no trace of cancer cells they can talk about complete pathological response.
It states that no cancer cells were found in the tissues removed, (which would be the original cancer site). It is more accurate than any diagnostic tool, as scans etc, will not pick up very small clusters of cancer cells, while the pathology tests do. Of course it doesn't offer any guarantees for the future, but it tells you that chemo has worked perfectly well in your case, while with adjuvant chemo you will never know (of course I'm talking about primary bc here).
Read this research (one of the authors is one of my oncologists!) for more info http://jco.ascopubs.org/cgi/content/full/24/7/1037
ciao
chiara |
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07-29-2009, 06:00 AM
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#7
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Member
Join Date: Dec 2007
Posts: 12
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Re: Complete response
Hi again Patty,
this is another useful article: http://theoncologist.alphamedpress.o...bstract/13/1/6
In case you're interested I was diagnosed nearly 2 years ago, grade 3, stage 3a, 4cm IDC, a lump of 2cm came up on the pet (it was clearly palpable), so one or more? lymphnode also affected. HER2 + but Er and Pr negative. went through 12 weeks of taxol + 12 weeks of FEC all accompanied by daily lapatinib and weekly herceptin. April 08 had surgery with the results I've already said. Just add my 6monthly check up and all is fine so far.
I'm finally feeling on top of things again, in control of my life and making the most of it! Enjoying my daughters and not worry )too much) about the future. Today I'm still here and life is good!
best of luck with the rest of your treatment,
chiara |
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