Re: DCIS & Neoadjuvant treatment - moving discussion to a new thread
I read further into the guidelines and found with breast conserving therapy a study of 215 patients showed an 8 year recurrence rate of 0% for low risk DICS, 21.5% for intermediate risk DCIS and 32.1% for high-risk DCIS.
A different study showed a 94% disease free survival rates with low risk DCIS, and 83% for both intermediate and high-risk DCIS over 10 years.
Later in the guidelines it states half of the local recurrences will be Invasive Ductal Carcinoma.
I did not see data on DCIS treated with mastectomy for recurrence rates in the guidelines.
Based on these numbers - if the goal to reduce recurrence perhaps Herceptin could make it into the guidelines. The studies will be worth watching.
I saw that IDC was found in 25% of the DCIS biopsies.
I think Sarah's decision for mastectomy was prudent, and not extreme - especially with intermediate and high risk DCIS.
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