HonCode

Go Back   HER2 Support Group Forums > Articles of Interest
Register Gallery FAQ Members List Calendar Search Today's Posts Mark Forums Read

Reply
 
Thread Tools Display Modes
Old 03-07-2021, 06:00 PM   #1
Nguyen
Senior Member
 
Join Date: Nov 2005
Posts: 304
CDK 4/6 Inhibitors Are Associated With a High Incidence of Thrombotic Events in Breas

CDK 4/6 Inhibitors Are Associated With a High Incidence of Thrombotic Events in Breast Cancer

https://onlinelibrary.wiley.com/doi/...ejh.13590?af=R

https://onlinelibrary.wiley.com/doi/...1111/ejh.13590
Nguyen is offline   Reply With Quote
Old 03-08-2021, 10:48 AM   #2
donocco
Senior Member
 
Join Date: Oct 2013
Posts: 446
Re: CDK 4/6 Inhibitors Are Associated With a High Incidence of Thrombotic Events in B

Nguyen

It goes beyond this. There was a trial using Faslodex alone vs Faslodex and Palbociclib (Ibrance) way back when. The combo extended the time of disease progression from 10 months (Faslodex alone) to 20 months, Faslodex plus Ibrance. This seems impressive.

Yet the important thing is overall survival, not time to progresssion. With Faslodex the overall survival median was 33 months. What about the Faslodex- Ibrance combo. Probably 66 months based on the time to progression info. Well not exactly. The overall survival median for the Ibrance Faslodex combination was 37 months.

Im not sating CDK 4,6 inhibitors are useless but their value is exaggerated by the nonstop advertising. "
donocco is offline   Reply With Quote
Reply

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is On

Forum Jump


All times are GMT -7. The time now is 07:05 PM.


Powered by vBulletin® Version 3.8.7
Copyright ©2000 - 2021, vBulletin Solutions, Inc.
Copyright HER2 Support Group 2007 - 2021
free webpage hit counter