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Old 12-22-2006, 08:02 AM   #1
heblaj01
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Join Date: Apr 2006
Posts: 543
Modified neural stem cells as a future treatment help for metastatic cancer

http://www.ivanhoe.com/channels/p_pr...?storyid=15169
Stem Cells Fight Cancer That has Spread

(extract...)

(Ivanhoe Newswire) -- There may soon be a new option for patients with advanced cancer that has spread throughout the body.

Researchers at City of Hope and St. Jude Children's Research Hospital in Duarte, Calif. report modified neural stem cells can activate and concentrate chemotherapy drugs mainly at tumor sites so the surrounding normal tissue is relatively unharmed.

"This approach could significantly improve future treatment options for patients with metastatic cancer," reports lead researcher Karen Aboody, M.D., from City of Hope. "It not only has the potential to destroy residual tumor cells, but it should also improve patients' quality of life by minimizing toxic side effects such as nausea, diarrhea, or bone marrow suppression.".....
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Old 03-07-2007, 08:33 AM   #2
alw
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Does anyone know how close this research is to Clinical Trials?

I'm bumping up this article to see if anyone has any information regarding neural stem cells and Dr Aboody's research.

It sounds so promising - does anyone know how close it is to clinical trials?

Regards,

Amy
__________________
Amy age 37 at dx
Feb 2008 Multifocal DCIS
Apr 2008 Bilateral Mastectomies

Sister to Laura age 37 at dx
April 2006
9 cm ER-/PR- Her2 +++/bone mets
neoadjuvant TCH plus Zometa
November 2006
bilateral mastectomy - Change to ER+/PR- Her2 +++
January 2007
innumerable tiny brain mets - WBR
March 2007
good response to WBR - some gone, all smaller
currently on Lapatinib and Xeloda
Feb 2008
Brain MRI: brain mets went from innumerable (jan '07) to 5 (june '07) to 3 (oct '07) to 1 that is getting less conspicuous(feb '08) PET/CT: Slight uptake in some sclerotic bone mets
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Old 03-07-2007, 11:51 AM   #3
heblaj01
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Amy,
I haven't the info your are seeking but you may get in touch with Dr Karen Aboody using this link:
http://www.cityofhope.org/Researcher...dyKarenBio.htm
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