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Old 06-11-2013, 11:30 AM   #1
yanyan
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Join Date: Apr 2011
Posts: 403
How long does it take for Kadcyla to work?

Today is day 12 since my 1st infusion. I know i am being very impatient and it is hard not to. I am not seeing much improvements on my skin mets- the rash is still there, red. I remember while on taxotere i could feel the tumor shrank in the 1st week but Kadcyla does not seem to work so fast.

For anyone of you who have been on Kadcyla, how long did it take to see any improvements? My oncologist said we probably won't see anything until we finish 2 sessions. As long as there is no progression, he considers it working. I feel discouraged as i have already failed herceptin and tykerb even though i am strongly HER2 positive.
__________________
1/11 age 36 DX
ER/PR-, Her2 +
TCH*6, Herceptin
BMX with immediate recontruction 5/2011 Lattismus Flap- Dx stage 3c 10/23 nodes
9/11 Radiation
3/12 Local recurrence to skin stage IV
Whole body scan CLEAR
4/12 Tykerb & Xeolda Skin mets slowly regressing
8/12 PET & Brain CT Clear
5/13 Skin mets progressing
6/13 PET scan chestwall recurrence in contralateral anxillary,internal mammary and ipsilateral subpectoral nodes
6/13 kadcyla
10/13 whole body scan -clear NED. previously resolved skin rash gone but 3 new lesions. Biopsy confirmed for skin recurrence
11/13 to 02/14 tykerb & herceptin
02/14 add abraxane/gemzar, 2 weeks on 1 week off at reduced dose
05/14 whole body PET clear/ brain CT clear but skin mets are getting worse, ready for new chemo
05/14 navelbine perjeta herceptin
07/14 skin mets progressing red rash worse
08/14 wide local excision with diep flap to close wound. Final path shows 2 positive margins showing inflammatory carcinoma Going back to surgery in 2 weeks
09/01/14 resection- clear margins
3 weeks after 2nd surgery, a new nodular rash found near drain incision with 2 small red spots behind the chest wall biopsy on 10/1. Positive for breast cancer
Radiation 11/2014 with xeloda then weekly cisplatin
11/14 brain MRI clean
12/14 finished 33 radiations burnt and very painful. Bedridden for 1 week
12/14 t current Herceptin and perjeta only
02/15 rash on upper back right side skin mets radiation planned
02/15 staring electron radiation *35
Stopped at 30 due to severe skin burn, resumed 10 days later
05/15 red patches appeared in between previously radiated area, skin mets. Ct and brain Mri clear. Simulation planned, radiation to start after trip to Alaska.
05/24 new spot identified in scar line on previously radiated reconstructed breast- electron on both side chest wall area and scar line
07/15 multiple skin and lung recurrence begin halaven
11/15 cough much better but very tired on halaven and starting to see some new red skin blotches-suspicious
11/15 heading to China for immune therapy
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Old 06-11-2013, 06:21 PM   #2
JennyB
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Re: How long does it take for Kadcyla to work?

Hi Yanyan,

I haven't been on Kadcycla but I have read lots of posts here about it being a slow starter so don't be discouraged hold on to what your onc says and 'patiently!!' wait - hard as I am sure it is!?
Prayers and thoughts are with you everyday from all over the world I wish I could do something to take your mind of the wait......
Good luck
Jenny x
__________________
Diagnosed Nov '10 IDC whilst pregnant with 2nd child
Her 2 ++ ER/PR + but weak and patchy 50% + 5%
Left mastectomy Dec '10, 6cm tumour 1 of 2 lymph (micro mets)
Clear margins but lymphovasculer invasion
Stage 3a Grade 3
Fec 100 x 3 Jan '11 Taxotere X 3 and Herceptin X 1yr
Staging scans - CT brain & body and bone - May '11 - NED!!
Start Femara - in chemo induced menapause
25 Rads June '11
Dec '11 Menstruation resumed - zoladex inj monthly and Tamoxifen
Feb '12 Back on Femera and Zoladex
March '12 CT brain & body & bone scan all clear
Zometa x2/yearly
April '12 - Oopherectomy

Praying the Herceptin is as good as its hype!!
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Old 06-12-2013, 02:56 PM   #3
phil
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Join Date: Nov 2010
Posts: 393
Re: How long does it take for Kadcyla to work?

for Lorraine, it took 3-4 doses to knock 7 liver mets to 4. her tumor mrkrs did drop w/in first 2 weeks or so. after 7 doses she had to dose reduce to 3.0 , due to platelet drop , but cancer still shrunk away over next 7-9 months or so. ned at about 11 months of tx., , still ned today , since nov., 2011. every ones response is a little different, but they usually don't do scans until after dose 3 or 4. Good Luck
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Old 06-13-2013, 10:11 AM   #4
yanyan
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Join Date: Apr 2011
Posts: 403
Re: How long does it take for Kadcyla to work?

Thanks ! I have skin mets so for me it is easy to see wheather or not it is working. I am getting 3.6 which is the FDA approved standard. Today is day 14 and I don't have the least nausea or fatigue. Everything feels so normal except that i get paranoid looking at my skin 10 times a day !
__________________
1/11 age 36 DX
ER/PR-, Her2 +
TCH*6, Herceptin
BMX with immediate recontruction 5/2011 Lattismus Flap- Dx stage 3c 10/23 nodes
9/11 Radiation
3/12 Local recurrence to skin stage IV
Whole body scan CLEAR
4/12 Tykerb & Xeolda Skin mets slowly regressing
8/12 PET & Brain CT Clear
5/13 Skin mets progressing
6/13 PET scan chestwall recurrence in contralateral anxillary,internal mammary and ipsilateral subpectoral nodes
6/13 kadcyla
10/13 whole body scan -clear NED. previously resolved skin rash gone but 3 new lesions. Biopsy confirmed for skin recurrence
11/13 to 02/14 tykerb & herceptin
02/14 add abraxane/gemzar, 2 weeks on 1 week off at reduced dose
05/14 whole body PET clear/ brain CT clear but skin mets are getting worse, ready for new chemo
05/14 navelbine perjeta herceptin
07/14 skin mets progressing red rash worse
08/14 wide local excision with diep flap to close wound. Final path shows 2 positive margins showing inflammatory carcinoma Going back to surgery in 2 weeks
09/01/14 resection- clear margins
3 weeks after 2nd surgery, a new nodular rash found near drain incision with 2 small red spots behind the chest wall biopsy on 10/1. Positive for breast cancer
Radiation 11/2014 with xeloda then weekly cisplatin
11/14 brain MRI clean
12/14 finished 33 radiations burnt and very painful. Bedridden for 1 week
12/14 t current Herceptin and perjeta only
02/15 rash on upper back right side skin mets radiation planned
02/15 staring electron radiation *35
Stopped at 30 due to severe skin burn, resumed 10 days later
05/15 red patches appeared in between previously radiated area, skin mets. Ct and brain Mri clear. Simulation planned, radiation to start after trip to Alaska.
05/24 new spot identified in scar line on previously radiated reconstructed breast- electron on both side chest wall area and scar line
07/15 multiple skin and lung recurrence begin halaven
11/15 cough much better but very tired on halaven and starting to see some new red skin blotches-suspicious
11/15 heading to China for immune therapy
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Old 06-13-2013, 10:21 AM   #5
schoonder
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Posts: 186
Re: How long does it take for Kadcyla to work?

Think Phil got it right, difficult to predict exact moment results of kadcyla, a personalized medicine, can be established. Linked article shows signs of efficacy, improved breathing, to occur after couple weeks; other symptoms might be slower to detect.

http://www.nbclosangeles.com/news/lo...200343881.html
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Old 06-13-2013, 02:55 PM   #6
yanyan
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Join Date: Apr 2011
Posts: 403
Re: How long does it take for Kadcyla to work?

I remember reading that post when Kadcyla was approved. My reaction was " wow "....

Update from my doctors visit:

1. I told him i didn't see much improvements in the skin... My doctor said " are you kidding me ?" - I was very happy to hear when he told me it improved a lot since he saw me last week on day 7. He also said he didn't expect to see any dramatic change with only one shot or within 1 week from the treatment

2. Pallates dropped to 18,000 on day 7 but bounced back to 108,000 today on day 14.
__________________
1/11 age 36 DX
ER/PR-, Her2 +
TCH*6, Herceptin
BMX with immediate recontruction 5/2011 Lattismus Flap- Dx stage 3c 10/23 nodes
9/11 Radiation
3/12 Local recurrence to skin stage IV
Whole body scan CLEAR
4/12 Tykerb & Xeolda Skin mets slowly regressing
8/12 PET & Brain CT Clear
5/13 Skin mets progressing
6/13 PET scan chestwall recurrence in contralateral anxillary,internal mammary and ipsilateral subpectoral nodes
6/13 kadcyla
10/13 whole body scan -clear NED. previously resolved skin rash gone but 3 new lesions. Biopsy confirmed for skin recurrence
11/13 to 02/14 tykerb & herceptin
02/14 add abraxane/gemzar, 2 weeks on 1 week off at reduced dose
05/14 whole body PET clear/ brain CT clear but skin mets are getting worse, ready for new chemo
05/14 navelbine perjeta herceptin
07/14 skin mets progressing red rash worse
08/14 wide local excision with diep flap to close wound. Final path shows 2 positive margins showing inflammatory carcinoma Going back to surgery in 2 weeks
09/01/14 resection- clear margins
3 weeks after 2nd surgery, a new nodular rash found near drain incision with 2 small red spots behind the chest wall biopsy on 10/1. Positive for breast cancer
Radiation 11/2014 with xeloda then weekly cisplatin
11/14 brain MRI clean
12/14 finished 33 radiations burnt and very painful. Bedridden for 1 week
12/14 t current Herceptin and perjeta only
02/15 rash on upper back right side skin mets radiation planned
02/15 staring electron radiation *35
Stopped at 30 due to severe skin burn, resumed 10 days later
05/15 red patches appeared in between previously radiated area, skin mets. Ct and brain Mri clear. Simulation planned, radiation to start after trip to Alaska.
05/24 new spot identified in scar line on previously radiated reconstructed breast- electron on both side chest wall area and scar line
07/15 multiple skin and lung recurrence begin halaven
11/15 cough much better but very tired on halaven and starting to see some new red skin blotches-suspicious
11/15 heading to China for immune therapy
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Old 06-13-2013, 05:52 PM   #7
schoonder
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Join Date: Jul 2008
Posts: 186
Re: How long does it take for Kadcyla to work?

Great news yanyan, very happy your doctor is seeing signs drug is doing the job.
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Old 06-14-2013, 02:04 PM   #8
KristinSchwick
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Location: Iowa
Posts: 231
Re: How long does it take for Kadcyla to work?

Yanyan, I've been on Kadcyla for 6 weeks, and just now did my tumor markers show benefit. Although the first few days after infusion, my bone mets ached and I felt pretty tired and stiff. However I felt overall much better in the weeks after my first infusion that I did prior to starting Kadcyla. Clinical response was early.
__________________
[B]Kristin
Aug 2010: diagnosed stage 3b, 4 mo. after birth of son. 29 yrs old and breastfeeding, ER/PR-, Her-2+ started Neoadjuvant therapy: 4x FEC, 10x abraxane & Herceptin
Feb 2011: L mx with recon. Path. showed only DCIS but 4/10+ nodes.
March 2011: 6 wks rads.
Mother passed, lower back pain.
Late May 2011: Bone mets but organs clear; Tykerb, Xeloda, Xgeva. Stopped Herceptin. Implant infected: removed implant.
October 2011: Bone progression; Gemzar and Carboplatin & restarted Herceptin.
Jan 2012: Progression, re-classified as ER+; Tykerb, Herceptin, Zoladex & Femara. Anti-E is working!
May 2012: ovaries out, markers stable but elevated. Cont. Herceptin, Tykerb, Xgeva & Femara.
Dec 2012: aromasin
Jan 2013: faslodex, herceptin, tykerb
Jun: Kadcyla
Aug: Rads to hip, then Perjeta, Herceptin & Taxotere
Nov 2013: Perjeta, Herceptin, Halaven
Early 2014: Affinitor, Aromasin, Perjeta, Herceptin.
June 2014: Estradiol, Perjeta, Herceptin
Aug 14: Tamoxofin, H & P
http://kristin-notdying-blog.blogspot.com/
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Old 06-15-2013, 01:49 PM   #9
yanyan
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Join Date: Apr 2011
Posts: 403
Re: How long does it take for Kadcyla to work?

Hi Kristen I'm glad to hear about ur response to kadcyla! My 2nd treatment is scheduled for next Thursday. As wierd as it may sound I am very looking forward to it. Somehow I like the chills muscle pains and headaches expected to happen on treatment day... I guess these side effects assure me that the drug is in my body doing its job.

Some pp are so fortunate to stay Ned on just herceptin alone for years and years! I wish more pp can have a response like that without developing resistance.
__________________
1/11 age 36 DX
ER/PR-, Her2 +
TCH*6, Herceptin
BMX with immediate recontruction 5/2011 Lattismus Flap- Dx stage 3c 10/23 nodes
9/11 Radiation
3/12 Local recurrence to skin stage IV
Whole body scan CLEAR
4/12 Tykerb & Xeolda Skin mets slowly regressing
8/12 PET & Brain CT Clear
5/13 Skin mets progressing
6/13 PET scan chestwall recurrence in contralateral anxillary,internal mammary and ipsilateral subpectoral nodes
6/13 kadcyla
10/13 whole body scan -clear NED. previously resolved skin rash gone but 3 new lesions. Biopsy confirmed for skin recurrence
11/13 to 02/14 tykerb & herceptin
02/14 add abraxane/gemzar, 2 weeks on 1 week off at reduced dose
05/14 whole body PET clear/ brain CT clear but skin mets are getting worse, ready for new chemo
05/14 navelbine perjeta herceptin
07/14 skin mets progressing red rash worse
08/14 wide local excision with diep flap to close wound. Final path shows 2 positive margins showing inflammatory carcinoma Going back to surgery in 2 weeks
09/01/14 resection- clear margins
3 weeks after 2nd surgery, a new nodular rash found near drain incision with 2 small red spots behind the chest wall biopsy on 10/1. Positive for breast cancer
Radiation 11/2014 with xeloda then weekly cisplatin
11/14 brain MRI clean
12/14 finished 33 radiations burnt and very painful. Bedridden for 1 week
12/14 t current Herceptin and perjeta only
02/15 rash on upper back right side skin mets radiation planned
02/15 staring electron radiation *35
Stopped at 30 due to severe skin burn, resumed 10 days later
05/15 red patches appeared in between previously radiated area, skin mets. Ct and brain Mri clear. Simulation planned, radiation to start after trip to Alaska.
05/24 new spot identified in scar line on previously radiated reconstructed breast- electron on both side chest wall area and scar line
07/15 multiple skin and lung recurrence begin halaven
11/15 cough much better but very tired on halaven and starting to see some new red skin blotches-suspicious
11/15 heading to China for immune therapy
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Old 07-15-2013, 10:10 AM   #10
yanyan
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Join Date: Apr 2011
Posts: 403
Re: How long does it take for Kadcyla to work?

Today is day 4 since my 3rd Kadcyla treatment. The results have been very encouraging. The redness on my breast is scaled down from 10 to 2, so i would say 80% gone ! My doctor thinks based on the speed it is going, it is likely to clear everything up with another 1 or 2 treatments. There will still be very light redness though, as he calls" residue". I still have bad pains all over and this time the low palates seem to have come in earlier as i am already seeing red spots and bruises, some chest congestion too. I am very amazed and thankful how people's life can turn around just within weeks !
__________________
1/11 age 36 DX
ER/PR-, Her2 +
TCH*6, Herceptin
BMX with immediate recontruction 5/2011 Lattismus Flap- Dx stage 3c 10/23 nodes
9/11 Radiation
3/12 Local recurrence to skin stage IV
Whole body scan CLEAR
4/12 Tykerb & Xeolda Skin mets slowly regressing
8/12 PET & Brain CT Clear
5/13 Skin mets progressing
6/13 PET scan chestwall recurrence in contralateral anxillary,internal mammary and ipsilateral subpectoral nodes
6/13 kadcyla
10/13 whole body scan -clear NED. previously resolved skin rash gone but 3 new lesions. Biopsy confirmed for skin recurrence
11/13 to 02/14 tykerb & herceptin
02/14 add abraxane/gemzar, 2 weeks on 1 week off at reduced dose
05/14 whole body PET clear/ brain CT clear but skin mets are getting worse, ready for new chemo
05/14 navelbine perjeta herceptin
07/14 skin mets progressing red rash worse
08/14 wide local excision with diep flap to close wound. Final path shows 2 positive margins showing inflammatory carcinoma Going back to surgery in 2 weeks
09/01/14 resection- clear margins
3 weeks after 2nd surgery, a new nodular rash found near drain incision with 2 small red spots behind the chest wall biopsy on 10/1. Positive for breast cancer
Radiation 11/2014 with xeloda then weekly cisplatin
11/14 brain MRI clean
12/14 finished 33 radiations burnt and very painful. Bedridden for 1 week
12/14 t current Herceptin and perjeta only
02/15 rash on upper back right side skin mets radiation planned
02/15 staring electron radiation *35
Stopped at 30 due to severe skin burn, resumed 10 days later
05/15 red patches appeared in between previously radiated area, skin mets. Ct and brain Mri clear. Simulation planned, radiation to start after trip to Alaska.
05/24 new spot identified in scar line on previously radiated reconstructed breast- electron on both side chest wall area and scar line
07/15 multiple skin and lung recurrence begin halaven
11/15 cough much better but very tired on halaven and starting to see some new red skin blotches-suspicious
11/15 heading to China for immune therapy
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Old 07-15-2013, 02:40 PM   #11
ElaineM
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Posts: 3,142
Wink Re: How long does it take for Kadcyla to work?

I am so happy to hear your skin mets are shrinking.
Have you ever tried sesame oil for platelets?
I had low platelets several years ago and my naturopathic physician suggested a spoon of sesame oil a day. It helped bring up the platelets.
__________________
Peace,
ElaineM
12 years and counting
http://her2support.org/vbulletin/showthread.php?t=48247
Lucky 13 !! I hope so !!!!!!
http://her2support.org/vbulletin/showthread.php?t=52807
14 Year Survivor
http://her2support.org/vbulletin/showthread.php?t=57053
"You never know how strong you are until being strong is the only choice you have." author unknown
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Old 07-15-2013, 03:45 PM   #12
'lizbeth
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Re: How long does it take for Kadcyla to work?

Wow - you Kadcyla gurus are my heros! This is just amazing to hear the good responses. I really hope that everyone gets to NED and has a long, long run on it.

So excited for you all to have this new option.

Phil, can you believe it is finally approved? One of the new ladies was offered the ATEMPT trial for the early breast cancer which compares TH to TDM1. Have you heard of any others?
__________________
Diagnosed 2007
Stage IIb Invasive Ductal Carcinoma, Pagets, 3 of 15 positive nodes

Traditional Treatment: Mastectomy and Axillary Node Dissection followed by Taxotere, 6 treatments and 1 year of Herceptin, no radiation
Former Chemo Ninja "Takizi Zukuchiri"

Additional treatments:
GP2 vaccine, San Antonio Med Ctr
Prescriptive Exercise for Cancer Patients
ENERGY Study, UCSD La Jolla

Reconstruction: TRAM flap, partial loss, Revision

The content of my posts are meant for informational purposes only. The medical information is intended for general information only and should not be used in any way to diagnose, treat, cure, or prevent disease
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Old 07-16-2013, 01:04 PM   #13
phil
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Posts: 393
Re: How long does it take for Kadcyla to work?

yanyan , so happy for you. such a quick response is a good indicator for continued benefits. like Lorraines experience. watch those plats.
hadn't heard of sesame oil for plats, i'll mention it to Lorraine.
i am excited that more pts will get t dm-1 earlier in the battle, been waiting for an adjuvant trial to compare it to taxanes. but how long will that trial take ? 3 yrs ? 4 ? if i was newly dx with a high her2 overexpression, i would give an adjuvant trial some serious thought.
still think the drug appr system needs a serious overhaul, the TDM-1 delay is just one sign of an FDA System that is too slow, out of touch with 21st century science , and the reality of the chemo rooms . You Stage IV 's have too few rights, and noone speaks for you at This FDA , a situation that we aim to change .
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Old 10-31-2013, 10:37 PM   #14
Tonya
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Location: n.c.
Posts: 9
Re: How long does it take for Kadcyla to work?

I am on my fourth dose of kadcyla and was wondering how many doses did you have before ca15-3 starting dropping? After the second dose it leveled off at 366 and next does only dropped it 6 points and now today it has taken a jump up over 150 points. My Doctor Wanted me to try one more round and check markers again. I am praying for a big miracle in the next 3 weeks to pull these markers back down. Any helpful information? bc2002 IV since 2007 liver mets, ovary involvement.Running out of options fast. Tonya
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Old 10-31-2013, 10:53 PM   #15
yanyan
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Join Date: Apr 2011
Posts: 403
Re: How long does it take for Kadcyla to work?

Hi Tonya! Has ur doctor mentioned perjeta? Although some insurance companies might deny coverage Genetech has a copayment assistance program and you may get free drug if your household income is less than $100,000.

My tumor markers have never been high. I get CEA and ca 27.29 tested every month. My CEA was always under 1 but went up to 3 while I am on Kadcyla. There are quite a few members here with liver mets and you may want to open a new thread on the treatment options for liver mets. Stay positive !!
__________________
1/11 age 36 DX
ER/PR-, Her2 +
TCH*6, Herceptin
BMX with immediate recontruction 5/2011 Lattismus Flap- Dx stage 3c 10/23 nodes
9/11 Radiation
3/12 Local recurrence to skin stage IV
Whole body scan CLEAR
4/12 Tykerb & Xeolda Skin mets slowly regressing
8/12 PET & Brain CT Clear
5/13 Skin mets progressing
6/13 PET scan chestwall recurrence in contralateral anxillary,internal mammary and ipsilateral subpectoral nodes
6/13 kadcyla
10/13 whole body scan -clear NED. previously resolved skin rash gone but 3 new lesions. Biopsy confirmed for skin recurrence
11/13 to 02/14 tykerb & herceptin
02/14 add abraxane/gemzar, 2 weeks on 1 week off at reduced dose
05/14 whole body PET clear/ brain CT clear but skin mets are getting worse, ready for new chemo
05/14 navelbine perjeta herceptin
07/14 skin mets progressing red rash worse
08/14 wide local excision with diep flap to close wound. Final path shows 2 positive margins showing inflammatory carcinoma Going back to surgery in 2 weeks
09/01/14 resection- clear margins
3 weeks after 2nd surgery, a new nodular rash found near drain incision with 2 small red spots behind the chest wall biopsy on 10/1. Positive for breast cancer
Radiation 11/2014 with xeloda then weekly cisplatin
11/14 brain MRI clean
12/14 finished 33 radiations burnt and very painful. Bedridden for 1 week
12/14 t current Herceptin and perjeta only
02/15 rash on upper back right side skin mets radiation planned
02/15 staring electron radiation *35
Stopped at 30 due to severe skin burn, resumed 10 days later
05/15 red patches appeared in between previously radiated area, skin mets. Ct and brain Mri clear. Simulation planned, radiation to start after trip to Alaska.
05/24 new spot identified in scar line on previously radiated reconstructed breast- electron on both side chest wall area and scar line
07/15 multiple skin and lung recurrence begin halaven
11/15 cough much better but very tired on halaven and starting to see some new red skin blotches-suspicious
11/15 heading to China for immune therapy
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Old 11-01-2013, 01:59 AM   #16
michka
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Posts: 858
Re: How long does it take for Kadcyla to work?

Hi Tonya. The only real measure is by scan. Your markers can also raise in the beginning because of dying cancer cells. Did you have a scan? Keep faith. Michka
__________________
08.2006 3 cm IDC Stage 2-3, HER2 3+ ER+90% PR 20%
FEC, Taxol+ Herceptin, Mastectomy, Radiation, Herceptin 1 year followed by Tykerb 1 year,Aromasin /Faslodex

12.2010 Mets to liver,Herceptin+Tykerb
03.2011 Liver resection ER+70% PR-
04.2011 Herceptin+Navelbine+750mg Tykerb
06.2011 Liver ned, Met to sternum. Added Zometa 09.2011 Cyberknife for sternum
11.2011 Pet clear. Stop Navelbine, continuing on Hercpetin+Tykerb+Aromasin
02.2012 Mets to lungs, nodes, liver
04.2012 TDM1, Ned in 07.2012
04.2015 Stop TDM1/Kadcyla, still Ned, liver problems
04.2016 Liver mets. Back on Kadcyla
08.2016 Kadcyla stopped working. mets to liver lungs bones
09.2016 Biopsy to liver. no more HER2, still ER+
09.2016 CMF Afinitor/Aromasin/ Xgeva.Met to eye muscle Cyberknife
01.2017 Gemzar/Carboplatin/ Ibrance/Faslodex then Taxotere
02.2017 30 micro mets to brain breathing getting worse and worse
04.2017 Liquid biopsy/CTC indicates HER2 again. Start Herceptin with Halaven
06.2017 all tumors shrunk 60% . more micro mets to brain (1mm mets) no symptoms
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Old 11-01-2013, 11:43 AM   #17
phil
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Posts: 393
Re: How long does it take for Kadcyla to work?

I agree with Michka. get a scan . Lorraine got a scan after 3 doses.
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