Herceptin / Tykerb Share your experiences or ask questions about Herceptin or Tykerb |
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07-20-2013, 11:16 AM
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#1
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Senior Member
Join Date: Apr 2008
Location: Sunny San Diego
Posts: 2,214
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Dr. Dennis Slamon, "our hero"
__________________
Diagnosed 2007
Stage IIb Invasive Ductal Carcinoma, Pagets, 3 of 15 positive nodes
Traditional Treatment: Mastectomy and Axillary Node Dissection followed by Taxotere, 6 treatments and 1 year of Herceptin, no radiation
Former Chemo Ninja "Takizi Zukuchiri"
Additional treatments:
GP2 vaccine, San Antonio Med Ctr
Prescriptive Exercise for Cancer Patients
ENERGY Study, UCSD La Jolla
Reconstruction: TRAM flap, partial loss, Revision
The content of my posts are meant for informational purposes only. The medical information is intended for general information only and should not be used in any way to diagnose, treat, cure, or prevent disease
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07-22-2013, 06:35 AM
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#2
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Senior Member
Join Date: Dec 2012
Location: Attica, IN
Posts: 371
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Re: Dr. Dennis Slamon, "our hero"
I enjoyed that video too! Thanks for posting it Ilizebeth and if you find more interesting ones keep posting. Afterall, there is nothing on TV in the summer and this is good stuff!
__________________
myleftlump.wordpress.com - started blogging my
IDC breast cancer
7/2012 diagnosed with multiple solid lesions
7/20/12 biopsy done. ER+ 30 PR -, HER+++,k167 80% Grade 2
9/2012 biopsy on lymph node - showed malignant
9/2012 Pre-adjunctive TCH chemo.
12/6/12 MRI after Pre-adj.
Results: Modest Decrease in size of left breast malignancy As well as the associated satellite lesions and auxiliary Adenopathy compared to prior study. Doctors hoped for better but good response it didn't grow.
12/18/2012 left masectomy with axillary nodes
Size 3.2 CM, Nottingham score 9/9
Grade 3, no evidence of in situ carcinoma
Areas of angiolymphatic are identified
Carcinoma is 0.5 cm from inked deep
Margin of excision
Attached axillary lymph nodes: metastatic
Carcinoma in 6 of 8 nodes.
Size of largest node 1.5 cm
Extracapsular
ER + 73%, PR+2%, HER2+
2/27/13 6 weeks of IMRT radiation finished
2/2013 Started on Tamoxifan 5 years.
8/2013 will take last Herceptin, 17 treatments total every 3 weeks.
BRCA1 & BRAC2 - Negative
August 28, 2013 DIEP flap on the left breast.
February 2014 Nip & Tuck
March 14, 2014 nipple reconstruction and removed port.
August 14, 2014 lump in lymph nodes under arm and above clavicle. Stage IV
August 28, 2014 herceptin And projeta starting and port put back in.
3/18/15 stopped arimidex.
3/18/15 progression....Tdm1
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07-22-2013, 07:41 AM
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#3
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Senior Member
Join Date: Apr 2008
Location: Sunny San Diego
Posts: 2,214
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Re: Dr. Dennis Slamon, "our hero"
There really is nothing on in the summer, I'll look for more interesting things.
In the Asian 5 element theory you and I are both highly expressed in our earth element. which is why we get on so well and drive others nuts with our accumulation of information and over the top friendliness. I can not learn enough!
__________________
Diagnosed 2007
Stage IIb Invasive Ductal Carcinoma, Pagets, 3 of 15 positive nodes
Traditional Treatment: Mastectomy and Axillary Node Dissection followed by Taxotere, 6 treatments and 1 year of Herceptin, no radiation
Former Chemo Ninja "Takizi Zukuchiri"
Additional treatments:
GP2 vaccine, San Antonio Med Ctr
Prescriptive Exercise for Cancer Patients
ENERGY Study, UCSD La Jolla
Reconstruction: TRAM flap, partial loss, Revision
The content of my posts are meant for informational purposes only. The medical information is intended for general information only and should not be used in any way to diagnose, treat, cure, or prevent disease
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07-22-2013, 08:45 AM
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#4
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Senior Member
Join Date: Dec 2012
Location: Attica, IN
Posts: 371
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Re: Dr. Dennis Slamon, "our hero"
Well, now I am going to have to google Asian 5 Element!!!! LOL.
I am a Virgo too does that mean anything??
But for TV I do have The Kardashian's Reality show DVR'd from last night maybe if I quit reading I will enjoy that tonight!! I am thinking of a path to walk if my back doesn't hurt too much after work. My tailbone has been really aching and it feels like a tooth I want to pull it out!! Geesh, always aches and pains.
__________________
myleftlump.wordpress.com - started blogging my
IDC breast cancer
7/2012 diagnosed with multiple solid lesions
7/20/12 biopsy done. ER+ 30 PR -, HER+++,k167 80% Grade 2
9/2012 biopsy on lymph node - showed malignant
9/2012 Pre-adjunctive TCH chemo.
12/6/12 MRI after Pre-adj.
Results: Modest Decrease in size of left breast malignancy As well as the associated satellite lesions and auxiliary Adenopathy compared to prior study. Doctors hoped for better but good response it didn't grow.
12/18/2012 left masectomy with axillary nodes
Size 3.2 CM, Nottingham score 9/9
Grade 3, no evidence of in situ carcinoma
Areas of angiolymphatic are identified
Carcinoma is 0.5 cm from inked deep
Margin of excision
Attached axillary lymph nodes: metastatic
Carcinoma in 6 of 8 nodes.
Size of largest node 1.5 cm
Extracapsular
ER + 73%, PR+2%, HER2+
2/27/13 6 weeks of IMRT radiation finished
2/2013 Started on Tamoxifan 5 years.
8/2013 will take last Herceptin, 17 treatments total every 3 weeks.
BRCA1 & BRAC2 - Negative
August 28, 2013 DIEP flap on the left breast.
February 2014 Nip & Tuck
March 14, 2014 nipple reconstruction and removed port.
August 14, 2014 lump in lymph nodes under arm and above clavicle. Stage IV
August 28, 2014 herceptin And projeta starting and port put back in.
3/18/15 stopped arimidex.
3/18/15 progression....Tdm1
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07-22-2013, 10:40 AM
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#5
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Senior Member
Join Date: Dec 2012
Location: Attica, IN
Posts: 371
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Re: Dr. Dennis Slamon, "our hero"
Interesting:
Earth dams (or muddies or absorbs) Water. Go figure!
__________________
myleftlump.wordpress.com - started blogging my
IDC breast cancer
7/2012 diagnosed with multiple solid lesions
7/20/12 biopsy done. ER+ 30 PR -, HER+++,k167 80% Grade 2
9/2012 biopsy on lymph node - showed malignant
9/2012 Pre-adjunctive TCH chemo.
12/6/12 MRI after Pre-adj.
Results: Modest Decrease in size of left breast malignancy As well as the associated satellite lesions and auxiliary Adenopathy compared to prior study. Doctors hoped for better but good response it didn't grow.
12/18/2012 left masectomy with axillary nodes
Size 3.2 CM, Nottingham score 9/9
Grade 3, no evidence of in situ carcinoma
Areas of angiolymphatic are identified
Carcinoma is 0.5 cm from inked deep
Margin of excision
Attached axillary lymph nodes: metastatic
Carcinoma in 6 of 8 nodes.
Size of largest node 1.5 cm
Extracapsular
ER + 73%, PR+2%, HER2+
2/27/13 6 weeks of IMRT radiation finished
2/2013 Started on Tamoxifan 5 years.
8/2013 will take last Herceptin, 17 treatments total every 3 weeks.
BRCA1 & BRAC2 - Negative
August 28, 2013 DIEP flap on the left breast.
February 2014 Nip & Tuck
March 14, 2014 nipple reconstruction and removed port.
August 14, 2014 lump in lymph nodes under arm and above clavicle. Stage IV
August 28, 2014 herceptin And projeta starting and port put back in.
3/18/15 stopped arimidex.
3/18/15 progression....Tdm1
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07-22-2013, 10:55 PM
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#6
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Senior Member
Join Date: Feb 2013
Location: Lincoln, NE
Posts: 265
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Re: Dr. Dennis Slamon, "our hero"
Salutations to "Our Hero!!!" Outstanding, once again, thank you for sharing...
I just sat back and was taken...the expertice of his knowledge, wisdom...what is to become...AMAZING THINGS ON THE HILL!!!
Perfect way to end my last day of chemo...FINALLY moving on to get my targeted Herceptin!!
And, yes, I do have a daughter...she is an RN, used to work in the critical care/burn unit, now in radiology...she is working on her MA...then, most probably on to NP...very intelligent young woman...and...so beautiful, of course I'm her mother!!
I had to add her to my "Timeline!!!" ![Smile](http://her2support.org/vbulletin/images/smilies/smile.gif)
Mister Sister...Gotta get you in there, too!!
__________________
10/18/12 Found pea size lump right breast
11/7/12 Biopsy
12/14/12 Lumpectomy
1/4/13 Rexcision, NO CLEAR MARGINS!! :(
2/11/13 Mastectomy with Expander Placed
2/15/13 INFECTION at Mastectomy site...emergency Surgery!!! Expander removed :(
DX: DCIS, IDC, Stage 2a, 2.7cm, 1/5 nodes positive
ER/PR-, HER2+++
3/28/13 Port placed
4/1/13 Begin 6 Cycles TCH Therapy
4/1/14 Finished Herceptin!!
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07-23-2013, 03:44 AM
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#7
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Senior Member
Join Date: Jul 2013
Location: Katonah,New York
Posts: 228
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Re: Dr. Dennis Slamon, "our hero"
Thanks so much for posting that...it is quite encouraging.I will be sure to keep Dr. Slamon in my prayers.
Congratulations SusanN on you last Chemo! What a wonderful day for you😀
__________________
3/11/13- normal mammo and US
4/30/13 Found pea sized lump while showering
5/10/13 core bx
5/15/13 dx IDC 1CM,
5/20/13 BRAC 1&2 neg
5/28/13 lumpectomy and SNB, ER/PR/Her-2+, Nodes neg,positive margins
6/13/13 revision of margins . Now clear
6/26/13 first TCH
Chemo Ninja~kutaki Zika Zukuchiri
10/18/13-Bx of calcification-neg whew
11/7/13 Started Radiation.
01/2014- Started Tamoxifen
06/09/14-Steriotactic BX left breast calcification-Benign
06/18/2014-completed one year of Herceptin!
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07-23-2013, 08:08 AM
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#8
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Senior Member
Join Date: Dec 2012
Location: Attica, IN
Posts: 371
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Re: Dr. Dennis Slamon, "our hero"
Yay, Susan for your last CHEMO!!!! I am sure you are on one happy camper right now knowing this is the last time you have to get this done, the last time you will have harsh SE's!!! That is a GREAT FEELING. Congrats!
And dang if your daughter is going to be a PA she will make some bank...I am sure you are extremely proud I would be!!
__________________
myleftlump.wordpress.com - started blogging my
IDC breast cancer
7/2012 diagnosed with multiple solid lesions
7/20/12 biopsy done. ER+ 30 PR -, HER+++,k167 80% Grade 2
9/2012 biopsy on lymph node - showed malignant
9/2012 Pre-adjunctive TCH chemo.
12/6/12 MRI after Pre-adj.
Results: Modest Decrease in size of left breast malignancy As well as the associated satellite lesions and auxiliary Adenopathy compared to prior study. Doctors hoped for better but good response it didn't grow.
12/18/2012 left masectomy with axillary nodes
Size 3.2 CM, Nottingham score 9/9
Grade 3, no evidence of in situ carcinoma
Areas of angiolymphatic are identified
Carcinoma is 0.5 cm from inked deep
Margin of excision
Attached axillary lymph nodes: metastatic
Carcinoma in 6 of 8 nodes.
Size of largest node 1.5 cm
Extracapsular
ER + 73%, PR+2%, HER2+
2/27/13 6 weeks of IMRT radiation finished
2/2013 Started on Tamoxifan 5 years.
8/2013 will take last Herceptin, 17 treatments total every 3 weeks.
BRCA1 & BRAC2 - Negative
August 28, 2013 DIEP flap on the left breast.
February 2014 Nip & Tuck
March 14, 2014 nipple reconstruction and removed port.
August 14, 2014 lump in lymph nodes under arm and above clavicle. Stage IV
August 28, 2014 herceptin And projeta starting and port put back in.
3/18/15 stopped arimidex.
3/18/15 progression....Tdm1
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07-23-2013, 09:47 AM
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#9
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Senior Member
Join Date: Apr 2008
Location: Sunny San Diego
Posts: 2,214
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Re: Dr. Dennis Slamon, "our hero"
We have lots of "Her2 Heroes" out there. He's one of the first, and most visible of our heroes. He was determined to get a treatment out for what was a terrible diagnosis at the time.
Thanks to him, and others, we have a treatment option: Herceptin. Prior to this being diagnosed with ER-, PR-, Her2+++ had some grim statistics.
As you will find with more reading the theory behind Herceptin that the original theory was the more highly expressed in receptors, the more effective Herceptin would be. I suspect this is why the cutoff was at Her2+++, and the low expressors were, unfortnately, left out of the original clinical trials.
Many times it difficult to let go of a belief, and the premise that higher expression of her2 was the key to stopping this disease persisted.
But, luckily for us, the discovery of the Her2 receptor was a significant finding that the cancer industry could focus on. When it was discovered that the original theory that focused on overexpression of Her2 being the sole reason for the growth of our cancer was a false premise, money poured into research for us.
Now some things were known, such as the ability of the Her2 receptor to dimerize (connect) with Her1 (EGFR), Her3, and Her4. Her2 was really a social butterfly and could connect up with any of the others. (Her1) EGFR could only hook up with Her1, Her3 to Her3, and Her4 to Her4.
Tykerb was the next targeted therapy with FDA approval for Her2 breast cancer, and I posted recently about how it works.
Perjeta is a recent approval of target therapy, and TDM1 (Kadcyla) is our most recent.
I truly believe TDM1 is a significant step toward better Western medicine treatments in cancer.
Now, as Lani (our unofficial board scientist) points out there have been many pathways discovered that the cancer uses to survive. She used the puppy example. I think we can all related to cancer - if someone is trying to take us out, we are going to do whatever is necessary to survive. So if someone blocks the Her2 pathways, we are simply going to find another path to walk on. Therefore, the enthusiasm and ongoing research to find new treatments to block these paths. I will leave questions in this area to Lani, as it is her expertise.
I, personally, want to see more treatments available and enthusiastically, and maybe a little too bluntly, try and steer everyone to a clinical trial. After being a cancer survivor, and a clincial trial participant, I've learned the system. If you go to most oncologists they can only offer standard of care. This is because of past mishaps, the ability to get approved for a clinical trial at one location is highly regulated. So many of the clinical trials are located at large cancer centers and teaching hospitals who have the experienced staff and the resources in place. Now, this is done by the FDA to protect us, the patient. But it makes it extremely difficult for enrollment into the trial. I had to travel from San Diego to San Antonio to participate in one of my trials.
So, if I come across more information from our Her2 Heroes, I'll post it. So we can know some of the important people who are working to keep us well.
__________________
Diagnosed 2007
Stage IIb Invasive Ductal Carcinoma, Pagets, 3 of 15 positive nodes
Traditional Treatment: Mastectomy and Axillary Node Dissection followed by Taxotere, 6 treatments and 1 year of Herceptin, no radiation
Former Chemo Ninja "Takizi Zukuchiri"
Additional treatments:
GP2 vaccine, San Antonio Med Ctr
Prescriptive Exercise for Cancer Patients
ENERGY Study, UCSD La Jolla
Reconstruction: TRAM flap, partial loss, Revision
The content of my posts are meant for informational purposes only. The medical information is intended for general information only and should not be used in any way to diagnose, treat, cure, or prevent disease
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07-24-2013, 07:44 AM
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#10
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Senior Member
Join Date: Apr 2008
Location: Sunny San Diego
Posts: 2,214
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Re: Dr. Dennis Slamon, "our hero"
http://www.youtube.com/watch?v=vsa7oTsYaEE
Dr Dennis Slamon's journey as the pioneer of Herceptin, inspires a movie of his life, LIVING PROOF.
__________________
Diagnosed 2007
Stage IIb Invasive Ductal Carcinoma, Pagets, 3 of 15 positive nodes
Traditional Treatment: Mastectomy and Axillary Node Dissection followed by Taxotere, 6 treatments and 1 year of Herceptin, no radiation
Former Chemo Ninja "Takizi Zukuchiri"
Additional treatments:
GP2 vaccine, San Antonio Med Ctr
Prescriptive Exercise for Cancer Patients
ENERGY Study, UCSD La Jolla
Reconstruction: TRAM flap, partial loss, Revision
The content of my posts are meant for informational purposes only. The medical information is intended for general information only and should not be used in any way to diagnose, treat, cure, or prevent disease
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07-24-2013, 08:26 AM
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#11
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Senior Member
Join Date: Dec 2012
Location: Attica, IN
Posts: 371
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Re: Dr. Dennis Slamon, "our hero"
I watched that movie right after I was diagnosed. What was really strange is my nephew in Iraq watched the movie and told me and my sister about it then we ended up watching it!
I remember thinking how sad that he had to turn people away from the trial and how people had to die and if they could have had herceptin they maybe could have lived. I have watched it a couple of times. Harry Connick Jr. plays the character and he is HOT!
__________________
myleftlump.wordpress.com - started blogging my
IDC breast cancer
7/2012 diagnosed with multiple solid lesions
7/20/12 biopsy done. ER+ 30 PR -, HER+++,k167 80% Grade 2
9/2012 biopsy on lymph node - showed malignant
9/2012 Pre-adjunctive TCH chemo.
12/6/12 MRI after Pre-adj.
Results: Modest Decrease in size of left breast malignancy As well as the associated satellite lesions and auxiliary Adenopathy compared to prior study. Doctors hoped for better but good response it didn't grow.
12/18/2012 left masectomy with axillary nodes
Size 3.2 CM, Nottingham score 9/9
Grade 3, no evidence of in situ carcinoma
Areas of angiolymphatic are identified
Carcinoma is 0.5 cm from inked deep
Margin of excision
Attached axillary lymph nodes: metastatic
Carcinoma in 6 of 8 nodes.
Size of largest node 1.5 cm
Extracapsular
ER + 73%, PR+2%, HER2+
2/27/13 6 weeks of IMRT radiation finished
2/2013 Started on Tamoxifan 5 years.
8/2013 will take last Herceptin, 17 treatments total every 3 weeks.
BRCA1 & BRAC2 - Negative
August 28, 2013 DIEP flap on the left breast.
February 2014 Nip & Tuck
March 14, 2014 nipple reconstruction and removed port.
August 14, 2014 lump in lymph nodes under arm and above clavicle. Stage IV
August 28, 2014 herceptin And projeta starting and port put back in.
3/18/15 stopped arimidex.
3/18/15 progression....Tdm1
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07-24-2013, 08:29 AM
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#12
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Senior Member
Join Date: Apr 2008
Location: Sunny San Diego
Posts: 2,214
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Re: Dr. Dennis Slamon, "our hero"
That is the name that slipped my mind "Harry Connick Jr". Thanks!
LOL, hmmm "HOT!". Shall I find out for you if he's single?
__________________
Diagnosed 2007
Stage IIb Invasive Ductal Carcinoma, Pagets, 3 of 15 positive nodes
Traditional Treatment: Mastectomy and Axillary Node Dissection followed by Taxotere, 6 treatments and 1 year of Herceptin, no radiation
Former Chemo Ninja "Takizi Zukuchiri"
Additional treatments:
GP2 vaccine, San Antonio Med Ctr
Prescriptive Exercise for Cancer Patients
ENERGY Study, UCSD La Jolla
Reconstruction: TRAM flap, partial loss, Revision
The content of my posts are meant for informational purposes only. The medical information is intended for general information only and should not be used in any way to diagnose, treat, cure, or prevent disease
Last edited by 'lizbeth; 07-24-2013 at 08:30 AM..
Reason: typo
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07-24-2013, 08:43 AM
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#13
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Senior Member
Join Date: Apr 2008
Location: Sunny San Diego
Posts: 2,214
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Re: Dr. Dennis Slamon, "our hero"
https://en.wikipedia.org/wiki/Harry_Connick,_Jr.
Oh . . . happily married, sorry! Wow, I had no idea of all his accomplishments.
__________________
Diagnosed 2007
Stage IIb Invasive Ductal Carcinoma, Pagets, 3 of 15 positive nodes
Traditional Treatment: Mastectomy and Axillary Node Dissection followed by Taxotere, 6 treatments and 1 year of Herceptin, no radiation
Former Chemo Ninja "Takizi Zukuchiri"
Additional treatments:
GP2 vaccine, San Antonio Med Ctr
Prescriptive Exercise for Cancer Patients
ENERGY Study, UCSD La Jolla
Reconstruction: TRAM flap, partial loss, Revision
The content of my posts are meant for informational purposes only. The medical information is intended for general information only and should not be used in any way to diagnose, treat, cure, or prevent disease
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07-24-2013, 08:44 AM
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#14
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Senior Member
Join Date: Apr 2008
Location: Sunny San Diego
Posts: 2,214
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Re: Dr. Dennis Slamon, "our hero"
__________________
Diagnosed 2007
Stage IIb Invasive Ductal Carcinoma, Pagets, 3 of 15 positive nodes
Traditional Treatment: Mastectomy and Axillary Node Dissection followed by Taxotere, 6 treatments and 1 year of Herceptin, no radiation
Former Chemo Ninja "Takizi Zukuchiri"
Additional treatments:
GP2 vaccine, San Antonio Med Ctr
Prescriptive Exercise for Cancer Patients
ENERGY Study, UCSD La Jolla
Reconstruction: TRAM flap, partial loss, Revision
The content of my posts are meant for informational purposes only. The medical information is intended for general information only and should not be used in any way to diagnose, treat, cure, or prevent disease
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07-24-2013, 08:47 AM
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#15
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Senior Member
Join Date: Dec 2012
Location: Attica, IN
Posts: 371
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Re: Dr. Dennis Slamon, "our hero"
He can play the piano, sing and act!! And you didn't know he was hot??? What the heck?? How could you not know this?? He has been in several movies. You need to watch more movies like I need to read more books. LOL
__________________
myleftlump.wordpress.com - started blogging my
IDC breast cancer
7/2012 diagnosed with multiple solid lesions
7/20/12 biopsy done. ER+ 30 PR -, HER+++,k167 80% Grade 2
9/2012 biopsy on lymph node - showed malignant
9/2012 Pre-adjunctive TCH chemo.
12/6/12 MRI after Pre-adj.
Results: Modest Decrease in size of left breast malignancy As well as the associated satellite lesions and auxiliary Adenopathy compared to prior study. Doctors hoped for better but good response it didn't grow.
12/18/2012 left masectomy with axillary nodes
Size 3.2 CM, Nottingham score 9/9
Grade 3, no evidence of in situ carcinoma
Areas of angiolymphatic are identified
Carcinoma is 0.5 cm from inked deep
Margin of excision
Attached axillary lymph nodes: metastatic
Carcinoma in 6 of 8 nodes.
Size of largest node 1.5 cm
Extracapsular
ER + 73%, PR+2%, HER2+
2/27/13 6 weeks of IMRT radiation finished
2/2013 Started on Tamoxifan 5 years.
8/2013 will take last Herceptin, 17 treatments total every 3 weeks.
BRCA1 & BRAC2 - Negative
August 28, 2013 DIEP flap on the left breast.
February 2014 Nip & Tuck
March 14, 2014 nipple reconstruction and removed port.
August 14, 2014 lump in lymph nodes under arm and above clavicle. Stage IV
August 28, 2014 herceptin And projeta starting and port put back in.
3/18/15 stopped arimidex.
3/18/15 progression....Tdm1
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07-24-2013, 09:11 AM
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#16
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Senior Member
Join Date: Dec 2012
Location: Attica, IN
Posts: 371
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Re: Dr. Dennis Slamon, "our hero"
Dr. Slamon is a handsome man, and I wonder if he can sing and play the piano!! He would have have the HIM+++. Meaning Him have the triple threat! LOL.
__________________
myleftlump.wordpress.com - started blogging my
IDC breast cancer
7/2012 diagnosed with multiple solid lesions
7/20/12 biopsy done. ER+ 30 PR -, HER+++,k167 80% Grade 2
9/2012 biopsy on lymph node - showed malignant
9/2012 Pre-adjunctive TCH chemo.
12/6/12 MRI after Pre-adj.
Results: Modest Decrease in size of left breast malignancy As well as the associated satellite lesions and auxiliary Adenopathy compared to prior study. Doctors hoped for better but good response it didn't grow.
12/18/2012 left masectomy with axillary nodes
Size 3.2 CM, Nottingham score 9/9
Grade 3, no evidence of in situ carcinoma
Areas of angiolymphatic are identified
Carcinoma is 0.5 cm from inked deep
Margin of excision
Attached axillary lymph nodes: metastatic
Carcinoma in 6 of 8 nodes.
Size of largest node 1.5 cm
Extracapsular
ER + 73%, PR+2%, HER2+
2/27/13 6 weeks of IMRT radiation finished
2/2013 Started on Tamoxifan 5 years.
8/2013 will take last Herceptin, 17 treatments total every 3 weeks.
BRCA1 & BRAC2 - Negative
August 28, 2013 DIEP flap on the left breast.
February 2014 Nip & Tuck
March 14, 2014 nipple reconstruction and removed port.
August 14, 2014 lump in lymph nodes under arm and above clavicle. Stage IV
August 28, 2014 herceptin And projeta starting and port put back in.
3/18/15 stopped arimidex.
3/18/15 progression....Tdm1
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07-24-2013, 10:20 AM
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#17
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Senior Member
Join Date: Apr 2008
Location: Sunny San Diego
Posts: 2,214
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Re: Dr. Dennis Slamon, "our hero"
LMAO, oh I'm so going to adopt the HIM+++ phrase.
I don't know too many of those, most are in the HIM++ category or lower, lol.
I did have one adorable doctor that turned the full force of his masculine charms on me in the hallway. I literally fell off my shoes, then made a hasty exit.
__________________
Diagnosed 2007
Stage IIb Invasive Ductal Carcinoma, Pagets, 3 of 15 positive nodes
Traditional Treatment: Mastectomy and Axillary Node Dissection followed by Taxotere, 6 treatments and 1 year of Herceptin, no radiation
Former Chemo Ninja "Takizi Zukuchiri"
Additional treatments:
GP2 vaccine, San Antonio Med Ctr
Prescriptive Exercise for Cancer Patients
ENERGY Study, UCSD La Jolla
Reconstruction: TRAM flap, partial loss, Revision
The content of my posts are meant for informational purposes only. The medical information is intended for general information only and should not be used in any way to diagnose, treat, cure, or prevent disease
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07-24-2013, 10:51 AM
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#18
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Senior Member
Join Date: Apr 2008
Location: Sunny San Diego
Posts: 2,214
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Re: Dr. Dennis Slamon, "our hero"
Oh, more movies with HOT men, you are soooo funny. I have a wonderful husband who is a jellybean. I try to avoid temptation! I typically do a good job too.
I hear George Clooney is available again, and the nice thing about dating him is his ex's seem to get a boob job. That might just work out really well for you right now.
__________________
Diagnosed 2007
Stage IIb Invasive Ductal Carcinoma, Pagets, 3 of 15 positive nodes
Traditional Treatment: Mastectomy and Axillary Node Dissection followed by Taxotere, 6 treatments and 1 year of Herceptin, no radiation
Former Chemo Ninja "Takizi Zukuchiri"
Additional treatments:
GP2 vaccine, San Antonio Med Ctr
Prescriptive Exercise for Cancer Patients
ENERGY Study, UCSD La Jolla
Reconstruction: TRAM flap, partial loss, Revision
The content of my posts are meant for informational purposes only. The medical information is intended for general information only and should not be used in any way to diagnose, treat, cure, or prevent disease
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07-24-2013, 11:24 AM
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#19
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Senior Member
Join Date: Dec 2012
Location: Attica, IN
Posts: 371
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Re: Dr. Dennis Slamon, "our hero"
First of all, oh my, George Clooney is definately my type!! He is Him+++ and me being HER2 aka social butterfly would fit him into my busy schedule for dinner !! Also, don't forget I will be getting a tummy tuck along with my new 20 year old breasts. However, I know with George it would go no further because he only believes in co-habitation, and that is not how I roll. I need more of a committment on my end. Next......
Secondly, your husband is a "Jelly Bean" interesting. Does he have a certain jelly belly flavor??? You typically do a good job??? Does that mean you sometimes do a bad job??? LOL!!!
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myleftlump.wordpress.com - started blogging my
IDC breast cancer
7/2012 diagnosed with multiple solid lesions
7/20/12 biopsy done. ER+ 30 PR -, HER+++,k167 80% Grade 2
9/2012 biopsy on lymph node - showed malignant
9/2012 Pre-adjunctive TCH chemo.
12/6/12 MRI after Pre-adj.
Results: Modest Decrease in size of left breast malignancy As well as the associated satellite lesions and auxiliary Adenopathy compared to prior study. Doctors hoped for better but good response it didn't grow.
12/18/2012 left masectomy with axillary nodes
Size 3.2 CM, Nottingham score 9/9
Grade 3, no evidence of in situ carcinoma
Areas of angiolymphatic are identified
Carcinoma is 0.5 cm from inked deep
Margin of excision
Attached axillary lymph nodes: metastatic
Carcinoma in 6 of 8 nodes.
Size of largest node 1.5 cm
Extracapsular
ER + 73%, PR+2%, HER2+
2/27/13 6 weeks of IMRT radiation finished
2/2013 Started on Tamoxifan 5 years.
8/2013 will take last Herceptin, 17 treatments total every 3 weeks.
BRCA1 & BRAC2 - Negative
August 28, 2013 DIEP flap on the left breast.
February 2014 Nip & Tuck
March 14, 2014 nipple reconstruction and removed port.
August 14, 2014 lump in lymph nodes under arm and above clavicle. Stage IV
August 28, 2014 herceptin And projeta starting and port put back in.
3/18/15 stopped arimidex.
3/18/15 progression....Tdm1
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07-24-2013, 12:01 PM
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#20
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Senior Member
Join Date: Feb 2013
Location: Lincoln, NE
Posts: 265
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Re: Dr. Dennis Slamon, "our hero"
GEEZZ, I do believe I JUST got "online" to some great stuff gals!! MUCH NEEDED as I woke up feeling YUCK with the LAST of these awful SE...
Yes, linn...thanks much as to your "Congrats!" Prayerfully and Trusting God, I NEVER want to relive chemo!!!! On to the "targeted" Herceptin...Monday...after having a thorough appt with MO, he said that the SE from Herceptin are 10x less than what I've just been through...something like that...
Just about when he "thought" I was finished addressing my questions...I asked him...as to the BBB not crossing the brain...he then closed the door & we talked for awhile, I felt comfortable in his answer...I CANNOT sit around worrying my life away...got to TRUST IN THE GOOD LORD ABOVE...some days are harder than others...quite the journey...CAN'T WAIT FOR MY LOCKS TO GROW BACK!!!!
As to my reconstruction...another story...we'll discuss it after the Herceptin is over...messed up situation there...he said half of breast reconstuctions have problems...I'm OF COURSE that half!!! Don't know IF I even want to try it again...especially after my expander had to be taken out, due to an infection...my extremely thin skin...and the fact that I hardly have any skin left to expand...and on a good day, I weigh in at about 115...don't really want any more skin cut from here or there...
Okay...enough of "poor pitiful me!!" I'd really like to watch Living Proof as well...was too vulnerable in the beginning, but could handle it now!!
Have an AWESOME day Beautiful Ladies!!! ![Smile](http://her2support.org/vbulletin/images/smilies/smile.gif)
__________________
10/18/12 Found pea size lump right breast
11/7/12 Biopsy
12/14/12 Lumpectomy
1/4/13 Rexcision, NO CLEAR MARGINS!! :(
2/11/13 Mastectomy with Expander Placed
2/15/13 INFECTION at Mastectomy site...emergency Surgery!!! Expander removed :(
DX: DCIS, IDC, Stage 2a, 2.7cm, 1/5 nodes positive
ER/PR-, HER2+++
3/28/13 Port placed
4/1/13 Begin 6 Cycles TCH Therapy
4/1/14 Finished Herceptin!!
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