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08-06-2008, 07:25 PM
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#1
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Junior Member
Join Date: Jul 2008
Posts: 1
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Has anyone tried Alpha Lipic Acid for Neuropathy?
Does anyone know if it is OK to take Alpha Lipic Acid for neuropathy (side effect from Taxol) while taking Herceptin?
Aug, 2007
Diagnosis: Invasive Ductal Carcinoma, Poorly Differentiated
Stage III Metastic
Node Positive
Her2+ Gene amplification 12.0 ratio
4 Rounds TAC, Taxotere, Adriamycin, Cytoxan
Weekly Herceptin
Bilateral Mastectomy, Dec.2007
Jan. 2008
Weekly Herceptin
3 Rounds Taxol
30 Radiation Treatments
Tried 2 monthly Herceptin went back to weekly
off Herceptin for couple weeks, side effects
Will finish Herceptin Jan.2009
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08-06-2008, 07:33 PM
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#2
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Senior Member
Join Date: Nov 2004
Location: Misty woods of WA State
Posts: 4,128
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I have taken Alpha LIPOIC Acid since it is a powerful antioxident. Not sure if this is the same thing as you asked about. Think I started taking it after finishing treatment for stage IV liver mets.
Did not take that for neuropathy, tho. Used the L-Glutamine powder.
__________________
"When I hear music, I fear no danger. I am invulnerable. I see no foe. I am related to the earliest times, and to the latest." H.D. Thoreau
Live in the moment.
MY STORY SO FAR ~~~~
Found suspicious lump 9/2000
Lumpectomy, then node dissection and port placement
Stage IIB, 8 pos nodes of 18, Grade 3, ER & PR -
Adriamycin 12 weekly, taxotere 4 rounds
36 rads - very little burning
3 mos after rads liver full of tumors, Stage IV Jan 2002, one spot on sternum
Weekly Taxol, Navelbine, Herceptin for 27 rounds to NED!
2003 & 2004 no active disease - 3 weekly Herceptin + Zometa
Jan 2005 two mets to brain - Gamma Knife on Jan 18
All clear until treated cerebellum spot showing activity on Jan 2006 brain MRI & brain PET
Brain surgery on Feb 9, 2006 - no cancer, 100% radiation necrosis - tumor was still dying
Continue as NED while on Herceptin & quarterly Zometa
Fall-2006 - off Zometa - watching one small brain spot (scar?)
2007 - spot/scar in brain stable - finished anticoagulation therapy for clot along my port-a-catheter - 3 angioplasties to unblock vena cava
2008 - Brain and body still NED! Port removed and scans in Dec.
Dec 2008 - stop Herceptin - Vaccine Trial at U of W begun in Oct. of 2011
STILL NED everywhere in Feb 2014 - on wing & prayer
7/14 - Started twice yearly Zometa for my bones
Jan. 2015 checkup still shows NED
2015 Neuropathy in feet - otherwise all OK - still NED.
Same news for 2016 and all of 2017.
Nov of 2017 - had small skin cancer removed from my face. Will have Zometa end of Jan. 2018.
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08-06-2008, 07:59 PM
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#3
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Senior Member
Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
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I did as part of a list given to me by my onc. also l gluatmine, acetyl l carnitine b6 and b12 coq10" ala is an antioxidant so don't overdo as some think it may interfere with certain chemos
__________________
Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial
5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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08-07-2008, 11:36 PM
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#5
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Guest
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supplements
My onc recommended the same supplements as Chrissy's when I was on taxotere/herceptin. I took them and suffered only mild neuropathy, which totally went away within a few months after finishing chemo.
Linda
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08-08-2008, 08:58 AM
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#6
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Senior Member
Join Date: Jan 2006
Location: New Jersey
Posts: 46
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I took alpha lipoic acid while I was on taxol. I had some pretty serious neuropathy problems, and the alpha lipoic acid seemed to help. It is also used for diabetics who have neuropathy issues.
Best,
Monica
__________________
Monica
Dx Nov 2003 HER2+++, ER+, PR+
1.7 cm. left breast, Grade 3, Two nodes out of six, stage IIA
Mastectomy right side
Lumpectomy left side
4 A/C, 4 Taxol plus 49 weeks herceptin
Radiation on left side
No tamoxifen or other hormonal drugs
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08-08-2008, 05:46 PM
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#7
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Senior Member
Join Date: Dec 2005
Location: Michigan
Posts: 230
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Interesting thread. Steph, how does L-Glutamine powder help w/ neuropathy?
And does anyone know if it can be improved even after having it for some time?
I recently have stopped my Enbrel (long story) but it boils down to seeing how my body will respond since the drs. still have no definitive answers about my inflammatory arthritis. Anyway, I am currently not having the joint inflammation but my neuropathy is considerably more noticeable now, especially when I wake up in the morn.
As always, any thoughts or suggestions would be appreciated.
Mar
__________________
Mary
Diagnosed 11/04 @39yrs. young
Stage IIB
2.5 cm, ER/PR- Her+++, grade 3
Partial Mast., 1/3 pos. node
1/05 full node dissection
4 A/C 4 Taxol DD, Herceptin 1 yr.
30X rads.
BRCA Negative
NED
Hope is the thing with feathers
That perches in the soul,
And sings the tune without the words,
And never stops at all -Emily Dickinson
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08-09-2008, 01:40 PM
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#8
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Senior Member
Join Date: May 2006
Posts: 3,142
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Has anyone tried Alpha Lipoic Acid
Aloha,
I have taken it for years since it is a powerful antioxidant.
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08-13-2008, 06:48 PM
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#9
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Senior Member
Join Date: Nov 2004
Location: Misty woods of WA State
Posts: 4,128
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Hi Mary -
Really not sure exactly HOW the L-glutimine works in the body - been too long to recall that. I know it DID help me and others.
Stopped at my local supplements store and remembered to ask about the Alpha Lipoid Acid for neuropathy. They said they do recommend it for that problem. Also, the lady clerk said she gives it to her husband who has type 1 diabetes for neuropathy as well as helping kidney function. One more pill for MY hubby! He just rolled his eyes when I told him ...
Guess as time goes on the propeller heads keep finding more uses for these compounds.
__________________
"When I hear music, I fear no danger. I am invulnerable. I see no foe. I am related to the earliest times, and to the latest." H.D. Thoreau
Live in the moment.
MY STORY SO FAR ~~~~
Found suspicious lump 9/2000
Lumpectomy, then node dissection and port placement
Stage IIB, 8 pos nodes of 18, Grade 3, ER & PR -
Adriamycin 12 weekly, taxotere 4 rounds
36 rads - very little burning
3 mos after rads liver full of tumors, Stage IV Jan 2002, one spot on sternum
Weekly Taxol, Navelbine, Herceptin for 27 rounds to NED!
2003 & 2004 no active disease - 3 weekly Herceptin + Zometa
Jan 2005 two mets to brain - Gamma Knife on Jan 18
All clear until treated cerebellum spot showing activity on Jan 2006 brain MRI & brain PET
Brain surgery on Feb 9, 2006 - no cancer, 100% radiation necrosis - tumor was still dying
Continue as NED while on Herceptin & quarterly Zometa
Fall-2006 - off Zometa - watching one small brain spot (scar?)
2007 - spot/scar in brain stable - finished anticoagulation therapy for clot along my port-a-catheter - 3 angioplasties to unblock vena cava
2008 - Brain and body still NED! Port removed and scans in Dec.
Dec 2008 - stop Herceptin - Vaccine Trial at U of W begun in Oct. of 2011
STILL NED everywhere in Feb 2014 - on wing & prayer
7/14 - Started twice yearly Zometa for my bones
Jan. 2015 checkup still shows NED
2015 Neuropathy in feet - otherwise all OK - still NED.
Same news for 2016 and all of 2017.
Nov of 2017 - had small skin cancer removed from my face. Will have Zometa end of Jan. 2018.
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