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Old 07-22-2010, 02:31 PM   #1
candlegranny
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nails falling off??

i am finished with my chemo, meeting with radiologist tomorrow morning. I wear acrylic nails. Never had a problem this whole time until yesterday. I was lifting some clothing and one of my nails popped off. It took my whole nail with it. mean there is nothing on the end of my finger! I also started trimming my toe nails and my big toe nail almost came off in my clippers, not it is missing all but a little spot of nail that is left. Is this a side effect of taxotere? how long do the side effects linger on? The watery eyes, no eyelashes, my skin itches all over and is very dry. My eyebrows itch awful I think i need to go soak these fake nails off and hope to save my nails instead of risking breaking another off.has anyone else suffered these side effects and if so what did you go for relief?
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Mammogram Sep 21, 2009 everything good and clear
DX jan 19,2010 Invasive Ductal Carcinoma, Grade 2 Age 56
modified radical masectomy on LEFT side 29 Jan 2010
2.7 cm 18/31 nodes
mets to just above collar bone ( 2 nodes showed in PET)
ER- PR - / Her2 +++ (IHC) Stage 111 C
ki-67 60% nottingham score 7
A/C chemo mar 22,2010 DD
herceptin & taxotere DD june 1,2010
finished taxotere july 12, 2010
finished herceptin 16 May 2011
PET Scan 9 Aug 10, cancer in neck is gone! NED
33 Rads completed 1 Oct 2010
PET/CT Scan 6 Jan 2011 NED
PET/CT Scan 3 Aug 2011
MUGA 59% 3/22/10 -63% 9/23/10 - 51% 1/4/11 - 55% 2/17/11 - 50% 8/3/11
26 Aug 2011 NED
20 Feb 2012 NED
5 Mar 2012 PORT OUT
12 July 2012 DIEP breast reconstruction
23 Aug 2012 NED
15 Nov 2012 new breast tweeked and natural breast uplifted and implant added
17 Feb 2013 NED
27 mar 2013 lipo suction to add fat cells to new breast in hopes for needed adjustment.


"Don't spend your time worrying about when or how you are going to die, spend your time figuring out how you are going to live today". ~Elizabeth Edwards.
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Old 07-22-2010, 02:52 PM   #2
MJo
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Re: nails falling off??

I don't know about taxotere, but AC definitely effects the nails. Mine turned black! They didn't fall off, but it might have been better if they had. Had to wait for them to grow out. I'm sure your nail problems are a side effect of all the chemo.
What did I do for relief? antidepressants and xanax!
As for the nails, I didn't do anything except hand cream and watching out for infection.
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IDC, Stage I, Grade 2
Oncotype DX Score 32
Her2++ E+P+, Node Neg.
Lumpectomy 11/04/05 Clear Margins
3 Dose dense AC (Couldn't tolerate 4)
4 Dose dense Taxol & Herc. (Tolerated well)
36 weeks Herceptin (Could not complete one year due to decrease in MUGA score)
2 years of Arimidex, then three years of Femara
Finished Femara May 2011
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Old 07-22-2010, 03:01 PM   #3
candlegranny
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Re: nails falling off??

is AC the adrimyacin and cytoxin? I had that in the beginning. I am doing good with coping I think just wanted an idea of when all this would be over. Guess I just need to keep positive and think with all the side effects, surely the chemo wiped out any left over cancer. I know it will get better I am just a little impatient.
__________________
Mammogram Sep 21, 2009 everything good and clear
DX jan 19,2010 Invasive Ductal Carcinoma, Grade 2 Age 56
modified radical masectomy on LEFT side 29 Jan 2010
2.7 cm 18/31 nodes
mets to just above collar bone ( 2 nodes showed in PET)
ER- PR - / Her2 +++ (IHC) Stage 111 C
ki-67 60% nottingham score 7
A/C chemo mar 22,2010 DD
herceptin & taxotere DD june 1,2010
finished taxotere july 12, 2010
finished herceptin 16 May 2011
PET Scan 9 Aug 10, cancer in neck is gone! NED
33 Rads completed 1 Oct 2010
PET/CT Scan 6 Jan 2011 NED
PET/CT Scan 3 Aug 2011
MUGA 59% 3/22/10 -63% 9/23/10 - 51% 1/4/11 - 55% 2/17/11 - 50% 8/3/11
26 Aug 2011 NED
20 Feb 2012 NED
5 Mar 2012 PORT OUT
12 July 2012 DIEP breast reconstruction
23 Aug 2012 NED
15 Nov 2012 new breast tweeked and natural breast uplifted and implant added
17 Feb 2013 NED
27 mar 2013 lipo suction to add fat cells to new breast in hopes for needed adjustment.


"Don't spend your time worrying about when or how you are going to die, spend your time figuring out how you are going to live today". ~Elizabeth Edwards.
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Old 07-22-2010, 03:49 PM   #4
tricia keegan
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Re: nails falling off??

I kept my own long manicured nails with a/c, (adriamycin/cytoxin) and it felt good to hang on to these after my hair fell out!!!

I had your experience with Taxol though, my eye lashes/brows went along with broken nails

Its best to keep them short for a time and hopefully no more will break off!! Mine were so long when they broke off I had to plaster's over them

It will pass once the tx is over so hang in there
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Tricia
Dx July '05 IDC 1.9cm Triple positive 3/9 nodes positive
A/C X 4 ..Taxol/Herceptin x 12 wks then herceptin 1 yr
Rads x 36 ..oophorectomy August '06
Currently taking Arimidex..
June 2011 osteopenia/ zometa x1 yearly- stopped Zometa 2015 as Dexa show normal bone density.
Stopped Arimidex July 2014- Restarted Arimidex 2015 for a further two years on the advice of my Onc.
2014 Normal Dexa scan
2018 Mammo all clear, still NED!
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Old 07-22-2010, 04:46 PM   #5
PinkGirl
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Re: nails falling off??

On taxol, my nails cracked off, peeled off, fell off .... and they
continued to give me grief while on herceptin. After herceptin they
went back to normal.
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Dx Aug/05 at age 51
2cm. Stage 2A, Grade 3
ER+/PR-
Her2 +++

Sept 7/05 Mastectomy
4 FAC, 4 Taxol, no radiation
1 year of Herceptin
Tamoxifen for approx. 4 months,
Arimidex for 5 years
Prophylactic mastectomy June 22/09



" I yam what I yam." - Popeye

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Old 07-22-2010, 08:33 PM   #6
Nancy L
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Re: nails falling off??

My fingernails all broke off about half way down and then fell off. I also lost both of my large toe nails. It was painful when it happened. I believe it was the Taxotere. I have been on Herceptin for over five years and Tykerb now for 16 months. My nails peel and I have them cut as short as possible. I was told not to wear artificial nails because of increased issues with infections. I used to wear gel nails and am considering trying them again.

Good luck with your treatment. Your nails will grow back but they probably won't be the same.
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Old 07-23-2010, 03:33 AM   #7
Ellie F
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Re: nails falling off??

Me to! Lost eyebrows and eyelashes with taxotere however the most painful part was when my big toe nails separated and bleed underneath. Didn't have problem with nails on AC just hair loss.

Ellie
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Old 07-23-2010, 07:12 AM   #8
caya
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Re: nails falling off??

I had crappy nails on Taxotere and Herceptin.
Like Pinky, these issues resolved after treatment.

I use 100% organic virgin coconut oil on my hands and feet (actually all over my body) and it helps immensely.
You only need a bit, but it goes a long way. Buy a jar at a health food store - a large jar costs $10 - $15 but will last for months.

all the best
caya
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ER90%+/PR 50%+/HER 2+
1.7 cm and 1.0 cm.
Stage 1, grade 2, Node Negative (16 nodes tested)
MRM Dec.18/06
3 x FEC, 3 x Taxotere
Herceptin - every 3 weeks for a year, finished May 8/08

Tamoxifen - 2 1/2 years
Femara - Jan. 1, 2010 - July 18, 2012
BRCA1/BRCA2 Negative
Dignosed 10/16/06, age 48 , premenopausal
Mild lymphedema diagnosed June 2009 - breast surgeon and lymph. therapist think it's completely reversible - hope so.
Reclast infusion January 2012
Oopherectomy October 2013
15 Years NED!!
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Old 07-23-2010, 07:17 AM   #9
michka
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Post Re: nails falling off??

8 toe nails fell out with Taxol. Nothing stopped it. The onc had told me it only happened with Taxotere... But my finger nails held on. Three or four were just a little brown. I had to wear oversized sport shoes. I understand how difficult it is for you. You can't do much about it but as you finished chemo now the process should reverse. My nails grew back like they were before even during Herceptin and then Tykerb. But it takes time. Michka
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08.2006 3 cm IDC Stage 2-3, HER2 3+ ER+90% PR 20%
FEC, Taxol+ Herceptin, Mastectomy, Radiation, Herceptin 1 year followed by Tykerb 1 year,Aromasin /Faslodex

12.2010 Mets to liver,Herceptin+Tykerb
03.2011 Liver resection ER+70% PR-
04.2011 Herceptin+Navelbine+750mg Tykerb
06.2011 Liver ned, Met to sternum. Added Zometa 09.2011 Cyberknife for sternum
11.2011 Pet clear. Stop Navelbine, continuing on Hercpetin+Tykerb+Aromasin
02.2012 Mets to lungs, nodes, liver
04.2012 TDM1, Ned in 07.2012
04.2015 Stop TDM1/Kadcyla, still Ned, liver problems
04.2016 Liver mets. Back on Kadcyla
08.2016 Kadcyla stopped working. mets to liver lungs bones
09.2016 Biopsy to liver. no more HER2, still ER+
09.2016 CMF Afinitor/Aromasin/ Xgeva.Met to eye muscle Cyberknife
01.2017 Gemzar/Carboplatin/ Ibrance/Faslodex then Taxotere
02.2017 30 micro mets to brain breathing getting worse and worse
04.2017 Liquid biopsy/CTC indicates HER2 again. Start Herceptin with Halaven
06.2017 all tumors shrunk 60% . more micro mets to brain (1mm mets) no symptoms
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Old 08-31-2010, 04:56 PM   #10
msleslie
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Re: nails falling off??

A couple of days ago two of my toe nails split straight across. I'm not sure how they are still hanging on. First no hair, no taste buds, now I learn I may have to give up my sexy shoes - WOW.
__________________
6/14/2010 - Self discovered Lump; Age 39
6/24/2010 - Biopsy results confirm breast cancer
Right breast, invasive ductal adenocarcinoma
HER2neu positive, BRAC I & II negative
7/8/2010 - Lumpectomy right breast, sentinel lymph node biopsy, & port-a-cath installed on left
Stage II, Size 3.2cm, Clear Nodes, Clear Margins
8/19/2010 - Chemo begins - Taxotere, Carboplatin, Herceptin & Tykerb all simulanteously; ALTTO trial arm 4
9/9/2010 - Chemo dose #2
9/30/2010 - Chemo dose#3
10/21/2010 - Chemo dose#4
11/11/2010 - Chemo dose#5
12/02/1010 - Chemo dose #6 - WooHoo, it is complete!
12/14/2010 - Simulation & Planning session for radiation
02/18/2011 - Completed radiation treatment (33 rounds)
08/04/2011 - Completed Herceptin & Tykerb
09/30/2013 - ultrasound guided biopsy (following annual MRI)
10/1/2013 - new cancer in left breast. 6mm discovered via MRI
10/28/2013 - bilateral mastectomy - no reconstruction
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Old 09-02-2010, 11:21 AM   #11
wlproctor
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Re: nails falling off??

My nails haven't fallen off but they are tissue thin. I have to keep them trimmed to the quick.
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Diagnosed 3/13/2009 from FNA, 39 years old.
4/09 lumpectomy with SNB, did not obtain clear margins.
5/09 - BMX with full axillary dissection on right side.
Final pathology report: 4cm+ high grade DCIS tumor with micro-invasive idc, 2/32 lymph nodes, ER/PR-, Her2+++, Stage IIa

7/09 - started TCH, finished 10/09
11/09 - 9 more months of Herceptin, finished 7/10

Reconstruction scheduled for Jan 2011

Expander placement completed - January 2011
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Old 09-05-2010, 09:35 AM   #12
Nina
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Re: nails falling off??

I have been on TCH since late April. Just finished. Nails have pealed and ripped, but I have kept the damage to a minimum by using a clear gel polish and keeping them very short. They have not fallen out or even loosened. Same with toe nails. They have even grown a tiny bit during this time.
__________________
Routine mammo 1/8/10
Ultrasound 1/22/10
Biopsy 2/2/10 - IDC, 2 cm, ER+, PR+, HER2 3+, Grade 3 (8/9)
Liver MRI (for other reason) on 2/12/10 clear - no mets
PET scan 3/5/10 - arm pit lymph nodes "lit up", no other areas of concern other than breast tumor
Lumpectomy 3/10 - tumor and all lymph nodes on left side removed
Pathology report results 3/19 show only 2 of 23 nodes removed were malignant, tumor margins were positive - additional surgery required
Second surgery 3/31/10
Pathology results 4/13/10- all margins clear
Stage 2a bc
Started TCH 4/30/10- finished 8/12/10 (2 more weeks of Herceptin to go)
9/2/10 - started Herceptin every three weeks
PET scan 9/18-10 - all well except shadowy area in lung
Started radiation 9/7/10 - finished 10/21/10
Aromasin started 11/1/10 (hate it!)
PET scan 12/13 area in lung is smaller - probably just inflamation
Aromasin stopped 1/14/11 due to side effects
Currently on AI holiday
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Old 09-05-2010, 07:04 PM   #13
msleslie
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Re: nails falling off??

I'm using a clear polish and avoiding remover. I'll just continue to reapply as needed. I also use an olive oil nail & cuticle treatment (looks just like a clear polish but is simply oil). In addition, my onc has recommended that I apply vicks rub to my nails daily to prevent them from turning yellow.
__________________
6/14/2010 - Self discovered Lump; Age 39
6/24/2010 - Biopsy results confirm breast cancer
Right breast, invasive ductal adenocarcinoma
HER2neu positive, BRAC I & II negative
7/8/2010 - Lumpectomy right breast, sentinel lymph node biopsy, & port-a-cath installed on left
Stage II, Size 3.2cm, Clear Nodes, Clear Margins
8/19/2010 - Chemo begins - Taxotere, Carboplatin, Herceptin & Tykerb all simulanteously; ALTTO trial arm 4
9/9/2010 - Chemo dose #2
9/30/2010 - Chemo dose#3
10/21/2010 - Chemo dose#4
11/11/2010 - Chemo dose#5
12/02/1010 - Chemo dose #6 - WooHoo, it is complete!
12/14/2010 - Simulation & Planning session for radiation
02/18/2011 - Completed radiation treatment (33 rounds)
08/04/2011 - Completed Herceptin & Tykerb
09/30/2013 - ultrasound guided biopsy (following annual MRI)
10/1/2013 - new cancer in left breast. 6mm discovered via MRI
10/28/2013 - bilateral mastectomy - no reconstruction
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