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Old 06-27-2009, 06:37 AM   #1
sassy
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Join Date: Sep 2005
Location: Mountains of Virginia
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Lani, Becky, All--Triple positive, node neg, herceptin use

Hey All,

I am working with a lady who was recently diagnosed as triple positive node negative. The only treatment mention to her so far has been tamoxifen.

I would like to arm her with some articles to take to her onc next week concerning use of Herceptin for early stage node negative (with or without chemo) and the use of AI over tamox.

What articles do you recommend?

Thanks for any help.
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Rhonda (Sassy)
dx age 45
DX 2/15/05 Stage IIb (at surgery)restaged IIIa
Left mast .9cm tumor 5 of 14 nodes
Triple Positive
4 DD A/C
12 Taxol/Herceptin
33Rads
Strange infect mast site one year aft surg, hosp 1 wk
Herceptin for total of 18 months
Lupron Monthly 4 yrs
Neurontin for aches, pains and hot flashes(It works!)
Ovaries removed 11/09 stop Lupron and Neurontin
Arimidex 6 yrs (tried Femara, no SE improvement)
Tried Exemestane-hips got so bad could hardly walk
Back to Arimidex for year seven
Zometa 2X Annual for 7years, Lasix
Stop Arimidex 5/13
Stop Zometa 7/13-Bi-lateral Stress Fractures in Femurs from Zometa
5/14 Start Tamoxifen
3/15 Stem cell transplant to stimulate femur bone growth/healing
5/15 Complete fracture of right femur/Titanium rods both femurs
9/16 Start Evista stopTamoxifen
3/17 Stop Evista--unwelcome side effects!
NED and no meds.......
14YEARS NED!
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Old 06-27-2009, 01:40 PM   #2
Becky
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Location: Stockton, NJ
Posts: 4,179
http://www.sabcs.org/Newsletter/Docs...008_Issue2.pdf
http://www.moffittcancercenter.com/C...n6/pdf/490.pdf
http://content.nejm.org/cgi/content/full/353/16/1734
http://arpa.allenpress.com/arpaonlin...E%5D2.0.CO%3B2
http://www.issoonline.com/content/5/1/9
http://www.medicalnewstoday.com/articles/133023.php
http://ww5.komen.org/ExternalNewsArt...x?newsID=42942

These should be enough. Look over - there are probably more. Unfortunately, I don't know your friend's stats to include something that even more indicative.
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Kind regards

Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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