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10-21-2012, 08:54 AM
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#1
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Senior Member
Join Date: Oct 2005
Location: New Jersey
Posts: 3,154
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This may explain why so many younger women are being dx.
__________________
Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
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10-21-2012, 11:07 AM
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#2
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Senior Member
Join Date: Apr 2008
Posts: 1,477
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Re: This may explain why so many younger women are being dx.
Jean,
Thanks for posting.
K
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10-21-2012, 11:11 AM
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#3
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Member
Join Date: Jul 2012
Posts: 19
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Re: This may explain why so many younger women are being dx.
I wonder if supplemental progesterone adds to that risk. I administered progesterone vaginally X 3 mos. for both my pregnancies and was diagnosed initially at age 40 when my second child was 2 yo. Anybody else have a similar experience?
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10-21-2012, 01:36 PM
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#4
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Senior Member
Join Date: Aug 2011
Location: Philly Suburbs
Posts: 1,709
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Re: This may explain why so many younger women are being dx.
Yep
I took large doses of progesterone during the first trimester of both of my pregnancies. And...my tumor was ER/PR negative.
Coincidence? Who knows!
But I do know that I wouldn't trade my two beautiful boys for anything...not even the chance to live to a ripe old age. If progesterone was the key to carrying full term...well...it was worth it...to me. But I hope other women have the risks explained to them, prior to treatment with progesterone...informed consent is never a bad thing.
Thanks for posting, Jean
Denise
__________________
1/11-needle biopsy
2/11-Lumpectomy/axillary node dissection - Stage 3c, ER/PR-14/17 nodes
3/11 - Post-op staph infection,cellulitis, lymphedema,seroma,ARRRGH!
4/12/11-A/C x 4, then T/H x 4, H only,Q3 weeks
8/26/11 finished Taxol!!!
10/7/11 mastectomy/DIEP recon
11/11 radiation x28
1/12/12 1st CANCER-VERSARY!
1/12 Low EF/Herceptin "Holiday" :(
2/12 EF up - Back on Herceptin, heart meds
4/2/1212 surgery to repair separated incision from DIEP recon
6/8/12 Return to work :)
6/17/12 Fall, shatter wrist,surgery to repair/insert plate :(
7/10/12 last Herceptin
7/23/12 Brain Mets %$&#! 3cm and 1cm
8/10/12 Gamma knife surgery, LOTS of steroids;start H/Tykerb
8/23/12 Back to work
12/20/12 Injure back-3 weeks in wheel chair
1/12/13 2nd CANCER-VERSARY!
1/14/13 herniate disk in back - surgery to repair
1/27/13 Radiation necrosis - edema in brain - back on steroids - but not back to work - off balance, poor cordination in right arm
5/3/13 Start Avastin to shrink necrosis
5/10/13 begin weaning steroids
6/18/13 Brain MRI - Avastin seems to be working!
6/20/13 quarterly CT - chest, abdomen, pelvis - All Clear!
7/5/13 finally off steroids!!
7/7/13 joined the ranks of the CHEMO NINJAS I am now Tekuto Ki Ariku cancer assassin!
7/13/13 Symptoms return - back on steroids
7/26/13 Back on Avastin - try again!
8/26/13 Not ready to return to classroom yet :( But I CAN walk without holding onto things! :)
9/9/13 Brain MRI - fingers crossed
“ Life is a grindstone, and whether it grinds you down or polishes you up is for you, and you alone, to decide. ” – Cavett Robert
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10-21-2012, 08:12 PM
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#5
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Senior Member
Join Date: Apr 2010
Posts: 129
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Re: This may explain why so many younger women are being dx.
I took Clomid to boost my progesterone levels for a total of 4 cycles. I have 2 kids as a result. I have always wondered if Clomid payed a role in my breast cancer. When I was first diagnosed, I suspected it because we had tried to get private medical insurance 2 years prior, but could not get coverage for me for 5 years post Clomid. The insurance companies must suspect a link. We could never figure out why they cared since it was literally 5 pills each cycle. They sure saved a lot of money by not covering me though! Instead, my husbands co got group insurance. This article makes me wonder about the link even more since my reason for taking Clomid was because my uterine lining was too thin to support a pregnancy. I kept miscarrying.
__________________
March 2010: Diagnosed with Stage IIIC IDC with axillary, mammary and suplaclavicular node involvement. ER/PR -, HER2+++. 7cm tumor in right breast.
April 2010: Started neoadjuvent chemo. 4 DD A/C every 2 weeks, 4 DD Taxotere every 3 weeks with Herceptin weekly.
August 2010: Finished chemo!
August 20, 2010: PET/CT showed no cancer in any nodes, and only a little uptake to the breast.
September 9, 2010: Bilateral mastectomy with immediate reconstruction with implants and Alloderm.
September 16, 2010: Pathology report showed 18/51 positive axillary nodes, 3.2cm tumor. Granual sized cancer found in the fatty tissue between levels 1 and 2.
October 19, 2010: CT showed several spots on lungs and 1 spot on liver. Liver spot is 2mm, lung spots range from 2mm to 4mm. We don't know if they are cancer or not.
12/15/10: Brain MRI clear
1/7/11: PET/CT
1/13/11: Recurrence in lungs. Start Tykerb
5/13/11: Progression in lungs
6/3/11: Lung surgery to get tumors for chemosensitivity testing.
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10-22-2012, 06:41 AM
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#6
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Senior Member
Join Date: Aug 2010
Posts: 58
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Re: This may explain why so many younger women are being dx.
me too deanna. i have always wondered if clomid was the kick starter for me. docs always said no since i was not er+. I took 3 months of clomid with no luck. i needed the chemo to make me fertile. odd but true.
__________________
Laureen (laurie)
Diagnosed 8/10/06 (found own lump)at 35
Her 2 +++, er-/pr-
4 A/C 8-29-06 to 11-06
Lumpectomy, node dissection- 11/30/06
Pathology report stage IIIC
1 tumor 3 cm
10 of 15 nodes +
12 Taxol 12/18/06-03/06/07
Herceptin 12/18/06- 12/11/2007 done!!! yeah!!!
33 rads started 3/22/07, done!! yeah!! 5/07/07
Lymphedema diagnosed 2/1/07
BRCA1/BRCA2 negative
port out 1/10/08
pregnant after 6 yeas of trying- due mid feb.
Ryder David born Feb. 6th 2009
Pregnant with baby #2, due in early june 2011.
*reach to recovery volunteer
*survivor recruitment committee -relay for life
*imerman angels
*making strides- team courage
*livestrong
*young survivor coalition YSC
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10-24-2012, 01:30 PM
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#7
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Senior Member
Join Date: Sep 2011
Location: Mt. Prospect, IL
Posts: 177
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Re: This may explain why so many younger women are being dx.
I did several cycles of clomid and about 4 IVF cycles, miscarried twice. I did progesterone injections with both pregnancies. I miscarried in August of 2010 and was Dx in October of 2010. I always wonder if that IVF cycle and the progesterone injections pumped up my tumor, a tumor that wasnt detected in September of 2009...
__________________
10/01/10 - Dx at age 44. Found lump after miscarrying & was told it was "probably a clogged milk duct" not so much:
stage II - invasive ductal carcinoma ER/PR+ HER2+
10/01/10 - BRCA test - Negative
11/3/10 -2.5cm tumor removed via lumpectomy, clear margins. sentinal node biopsy - nodes clear!
12/2/10 - port placement
12/2/10 to 3/17/11 - 6 rounds of taxotere, carboplatin & herceptin every 3rd week.
04/20/11 - 6/6/11 - 33 rounds of radiation
4/6/11 to 11/2/11 - 11 additional rounds of herceptin every 3rd week
7/15/11 - port removal
7/5/11 started my 5 year journey on Tamoxifen
9/4/11 -1 yr Chest MRI - CLEAN!!!!
9/5/12 -2 yr Chest MRI - CLEAN!!!!
8/29/12 - Started spotting after being in chemopause 1.5 years. Ultra sound detected 6cm ovary mass & very thick lining. YIKES! Taken off Tamoxifen
9/6/12 - Full abdominal hysterectomy. Pathology report came back clean... thank you baby Jesus!!
9/28/12 - Started Anastrozole
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10-24-2012, 02:45 PM
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#8
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Senior Member
Join Date: Jan 2008
Location: "Love never fails."
Posts: 5,808
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Re: This may explain why so many younger women are being dx.
I went through three months of hormone shots and two artificial inseminations when I was 38 but did not result in pregnancy. Instead I got three uterine fibroids. Then I was prescribed birth control pill to curb the growth of the fibroids. Five years after the initial treatment I was diagnosed with breast cancer. The first thing my gynecologist told me (after I'd called and told him about the bc diagnosis) was to quit taking the birth control pills.
__________________
Jackie07
http://www.kevinmd.com/blog/2011/06/doctors-letter-patient-newly-diagnosed-cancer.html
http://www.asco.org/ASCOv2/MultiMedi...=114&trackID=2
NICU 4.4 LB
Erythema Nodosum 85
Life-long Central Neurocytoma 4x5x6.5 cm 23 hrs 62090 semi-coma 10 d PT OT ST 30 d
3 Infertility tmts 99 > 3 u. fibroids > Pills
CN 3 GKRS 52301
IDC 1.2 cm Her2 +++ ER 5% R. Lmptmy SLNB+1 71703 6 FEC 33 R Tamoxifen
Recc IIB 2.5 cm Bi-L Mast 61407 2/9 nds PET
6 TCH Cellulitis - Lymphedema - compression sleeve & glove
H w x 4 MUGA 51 D, J 49 M
Diastasis recti
Tamoxifen B. scan
Irrtbl bowel 1'09
Colonoscopy 313
BRCA1 V1247I
hptc hemangioma
Vertigo
GI - > yogurt
hysterectomy/oophorectomy 011410
Exemestane 25 mg tab 102912 ~ 101016 stopped due to r. hip/l.thigh pain after long walk
DEXA 1/13
1-2016 lesions in liver largest 9mm & 1.3 cm onco. says not cancer.
3-11 Appendectomy - visually O.K., a lot of puss. Final path result - not cancer.
Start Vitamin D3 and Calcium supplement （600mg x2)
10-10 Stopped Exemestane due to r. hip/l.thigh pain OKed by Onco 11-08-2016
7-23-2018 9 mm groundglass nodule within the right lower lobe with indolent behavior. Due to possible adenocarcinoma, Recommend annual surveilence.
7-10-2019 CT to check lung nodule.
1-10-2020 8mm stable nodule on R Lung, two 6mm new ones on L Lung, a possible lymph node involvement in inter fissule.
"I WANT TO BE AN OUTRAGEOUS OLD WOMAN WHO NEVER GETS CALLED AN OLD LADY. I WANT TO GET SHARP EDGED & EARTH COLORED, TILL I FADE AWAY FROM PURE JOY." Irene from Tampa
Advocacy is a passion .. not a pastime - Joe
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10-24-2012, 06:41 PM
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#9
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Senior Member
Join Date: Jul 2011
Location: Melbourne, Australia
Posts: 432
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Re: This may explain why so many younger women are being dx.
I took the pill but didn't have any fertility treatment - I did miscarry 3 times and had three healthy pregnancies.
At my support group today we were discussing fertility treatments and 3 of the girls had fertility treatment and now secondary cancer - non are her2 positive though.
__________________
Amanda xx
40 year old Mum to three gorgeous kids - son 5 and daughters 8 and 11
Wife to my wonderfully supportive husband of 17 years!
22 February 2011 - Diagnosed Early Breast Cancer IDBC Stage2b (ER/PR -ve, Her2+ve +++) - 38 years old
(L) skin sparing mastectomy with tissue expander, axilla clearance (2/14 affected) clear margins.
Fec*3, Taxotere and herceptin*2 - stopped due to secondary diagnosis
June 24 2011 Stage IV - Skin met, axilla node, multiple lung lesions
Bolero3 trial - Navelbine, Hereptin weekly, daily Everolimus/Placebo
February 2012 - July 2012 Tykerb and Xeloda - skin mets resolved, Lungs initially dramatically reduced but growing again
August 2012 (turn 40!) tykerb and herceptin (denied compassionate use of TDM1) while holidaying in Italy!
September 2012 - January 2013 TDM1 as part of the Th3resa trial - lymph nodes resolved, lungs slowly progressing.
January 2013 - herceptin, carboplatin and Perjeta (compassionate access)
April 2013 - Some progression in lungs and lymph nodes - Abraxane, Herceptin and Perjeta
July 2013 - mixed response - dramatic reduction of most lung disease, progression of smaller lung nodules and cervical and hilar nodes - ? Add avastin.
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10-24-2012, 07:11 PM
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#10
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Senior Member
Join Date: Oct 2012
Posts: 45
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Re: This may explain why so many younger women are being dx.
I took birth control pills for years and years for irregular cycles. Then, when I did become pregnant, I had horrible morning sickness. They say morning sickness is from having a bunch of hormones to support the pregnancy. They should research morning sickness and risk of breast cancer.
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