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03-11-2014, 12:40 PM
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#1
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Senior Member
Join Date: Aug 2013
Location: Texas
Posts: 61
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Elevated CPK and Myoglobin ???
Hi All,
Well of course here I am asking yet another question. :-)
My Onc recently called me back into the office for additional blood work as it appears my CPK and Myoglobin levels are elevated. She didn't give me specific numbers but wanted me to get them checked again. I had surgery Tuesday of last week and then had my herceptin treatment and blood work done on Thursday. So she is thinking it may have something to do with the recent surgery. Therefore I went in this week and had blood work done again. She hasn't called me with the results yet but I wanted to get some feed back on what exactly this means. I read online it has something to do with the muscles which could explain the weakness and achy muscles I have been having since chemo in Jan. The aches and weakness feel like they are getting better but it is still there.
Has anyone had issues with their CPK and/or Myoglobin levels? Is there anything they can do to help get them back on track if they still are elevated?
Thank you all in advance!!
__________________
Lovemyboy3
6/27/2013 - Diagnostic Mammogram due to a tiny lesion found.
6/27/13 - Diagnosed with Breast Cancer at age 33 :'(
07/11/2013 - Surgical needle biopsy
07/15/2013 - Path report results from biopsy - DCIS with micro invasion, Pagents disease - ER/PR- Her2+++
7/26/13 - PET Scan CLEAR!!
8/19/13 - B/L Mastectomy w/DIEP Flap reconstructive surgery. Nodes removed clear!! Stage 1A. Positive Margins remaining
8/23/13 - Finally HOME from the hospital
9/10/13 - All drains out. YEAH!!
9/6/13 - 2nd Surgery to try and remove remaining positive margins. Port placed.
9/11/13 - Path report shows all tissue samples are neg. Clear Margins!!
10/3/13 First TCH treatment - Horrible amount of side effects.
11/10/11 - First weekly Herceptin treatment.
10/11/13 - Late night ER visit due to Neutropenic fever - WBC at 0 in the hospital.
11/17/13 - Ultrasound on left breast due to pain. Benign findings: Oil cysts and possible Fat Neurosis from reconstructive surgery.
11/24/13 - Round 2 TCH treatment.
11/25/13 - Neulasta Shot given. Side effects minimal. Woo Hoo!
11/27/13 - Said goodbye to my hair. :-(
01/14 - Mammogram and Ultra sound - CLEAR!
01/23/14 - Last scheduled Chemo! WOO HOO!
03/04/14 - Phase 2&3 reconstructive surgery DONE!
03/06/14 - 2 days after surgery and 1st Herceptin only treatment. Minimal side affects.
03/14 - Began having pain and weakness in my feet and legs. Doc thinks it is delayed side affects of chemo possibly Neuropathy. Could even be the Herceptin (what ever it is I would appreciate it if it went away :/)
03/14 - A little over 8 wks post chemo and hair is about 1/2in long. :) Not a whole lot but its getting there. Eyebrows are taking there time but are coming in nicely.
04/14 - Where did my eyelashes go? :/
16 Rejoice always, 17 pray continually, 18 give thanks in all circumstances; for this is God’s will for you in Christ Jesus.
1 Thessalonians 5:16-18
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03-12-2014, 09:09 PM
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#2
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Senior Member
Join Date: Jan 2008
Location: "Love never fails."
Posts: 5,808
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Re: Elevated CPK and Myoglobin ???
Hi,
What I've learned over the years is that if the doctor did not call me right away after a procedure/test, then everything was O.K.
That does not mean I wasn't anxious about the test results...
I'm thinking what your doctor is doing is probably similar to the echocardiogram to monitor the heart. Except the blood test is easier/cheaper/faster and can be done more frequently.
Sending you good vibes.
__________________
Jackie07
http://www.kevinmd.com/blog/2011/06/doctors-letter-patient-newly-diagnosed-cancer.html
http://www.asco.org/ASCOv2/MultiMedi...=114&trackID=2
NICU 4.4 LB
Erythema Nodosum 85
Life-long Central Neurocytoma 4x5x6.5 cm 23 hrs 62090 semi-coma 10 d PT OT ST 30 d
3 Infertility tmts 99 > 3 u. fibroids > Pills
CN 3 GKRS 52301
IDC 1.2 cm Her2 +++ ER 5% R. Lmptmy SLNB+1 71703 6 FEC 33 R Tamoxifen
Recc IIB 2.5 cm Bi-L Mast 61407 2/9 nds PET
6 TCH Cellulitis - Lymphedema - compression sleeve & glove
H w x 4 MUGA 51 D, J 49 M
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Tamoxifen B. scan
Irrtbl bowel 1'09
Colonoscopy 313
BRCA1 V1247I
hptc hemangioma
Vertigo
GI - > yogurt
hysterectomy/oophorectomy 011410
Exemestane 25 mg tab 102912 ~ 101016 stopped due to r. hip/l.thigh pain after long walk
DEXA 1/13
1-2016 lesions in liver largest 9mm & 1.3 cm onco. says not cancer.
3-11 Appendectomy - visually O.K., a lot of puss. Final path result - not cancer.
Start Vitamin D3 and Calcium supplement （600mg x2)
10-10 Stopped Exemestane due to r. hip/l.thigh pain OKed by Onco 11-08-2016
7-23-2018 9 mm groundglass nodule within the right lower lobe with indolent behavior. Due to possible adenocarcinoma, Recommend annual surveilence.
7-10-2019 CT to check lung nodule.
1-10-2020 8mm stable nodule on R Lung, two 6mm new ones on L Lung, a possible lymph node involvement in inter fissule.
"I WANT TO BE AN OUTRAGEOUS OLD WOMAN WHO NEVER GETS CALLED AN OLD LADY. I WANT TO GET SHARP EDGED & EARTH COLORED, TILL I FADE AWAY FROM PURE JOY." Irene from Tampa
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03-13-2014, 01:01 AM
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#3
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Senior Member
Join Date: Jul 2013
Posts: 260
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Re: Elevated CPK and Myoglobin ???
Dear Lovemyboys3,
Lots of causes for this and unlikely for there to be a real problem. It is a sign of muscle damage of any sort. Probably shouldn't have had that blood test and you'd be none the wiser. Almost certainly due to the recent surgery. Can even occur with heavy exercise. Should be trending down on the subsequent tests.
The oncologist is being cautious - inflammation in the muscle due to an immune disorder (eg. polymyositis, dermatomyositis) can cause the CPK and myoglobin to rise. This is unlikely, unless you had the condition prior to chemo. Immune disorders like this, or rheumatoid arthritis, can rebound once chemo ceases.
During chemo, there is muscle damage and I expect this would cause some rise in these tests, which would resolve as the muscles heal (takes a few months at least). I think it was bad timing to have these tests so soon after chemo and especially the operation!
Hope you find out the results soon, but I suspect your oncologist won't be too worried.
Aussie Girl
__________________
31mm Infiltrating duct carcinoma
Grade 3, ER/PR-, HER2+, Neg Sentinel nodes x 5
49mm field of DCIS
17 June '13: Screen detected impalpable mass, Mammogram neg, US.
25 June '13: Diagnosed after multiple biopsies and MRIs
28 June '13: Left lumpectomey
4 July '13: Left Mastectomy
12 August '13: Commenced TCH chemo
Mid December '13 : TCH finished. Herceptin continuing three weekly.
4 August 2014- Herceptin infusions finished.
END OF THERAPY - YAY!
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03-13-2014, 08:11 AM
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#4
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Senior Member
Join Date: Dec 2012
Location: Attica, IN
Posts: 371
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Re: Elevated CPK and Myoglobin ???
Aussie girl, I just had a complete panel done....I am taking vitamins and my RBC was "very low" it said 3.45 and my hemoglobin was low and MCV I think it was low too!!
What is the biggest deal with the low RBC and hemoglobin...Does it just mean I am anemic??
__________________
myleftlump.wordpress.com - started blogging my
IDC breast cancer
7/2012 diagnosed with multiple solid lesions
7/20/12 biopsy done. ER+ 30 PR -, HER+++,k167 80% Grade 2
9/2012 biopsy on lymph node - showed malignant
9/2012 Pre-adjunctive TCH chemo.
12/6/12 MRI after Pre-adj.
Results: Modest Decrease in size of left breast malignancy As well as the associated satellite lesions and auxiliary Adenopathy compared to prior study. Doctors hoped for better but good response it didn't grow.
12/18/2012 left masectomy with axillary nodes
Size 3.2 CM, Nottingham score 9/9
Grade 3, no evidence of in situ carcinoma
Areas of angiolymphatic are identified
Carcinoma is 0.5 cm from inked deep
Margin of excision
Attached axillary lymph nodes: metastatic
Carcinoma in 6 of 8 nodes.
Size of largest node 1.5 cm
Extracapsular
ER + 73%, PR+2%, HER2+
2/27/13 6 weeks of IMRT radiation finished
2/2013 Started on Tamoxifan 5 years.
8/2013 will take last Herceptin, 17 treatments total every 3 weeks.
BRCA1 & BRAC2 - Negative
August 28, 2013 DIEP flap on the left breast.
February 2014 Nip & Tuck
March 14, 2014 nipple reconstruction and removed port.
August 14, 2014 lump in lymph nodes under arm and above clavicle. Stage IV
August 28, 2014 herceptin And projeta starting and port put back in.
3/18/15 stopped arimidex.
3/18/15 progression....Tdm1
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03-14-2014, 03:50 AM
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#5
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Senior Member
Join Date: Jul 2013
Posts: 260
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Re: Elevated CPK and Myoglobin ???
Dear Linn,
Yes, those counts mean you are anemic. If the MCV was low, it might be iron deficiency, although some hereditary blood cell disorders cause it. If you had a low MCV all your life, it might be hereditary. Iron deficiency is very common and chemo puts demands on your internal iron stores. You have had surgery recently, but that would only tip you into anemia if you were already low. You might need an iron supplement. Also you might need to be checked for blood loss (from the gut, from heavy periods etc.)
If the MCV was high there are lots of causes - mainly low folate or Vit B12, but also drugs (including chemo drugs), alcohol, low thyroid function etc.
Your doctor should be able to work this out for you. Getting your red cell count back to normal will help you feel much better.
Aussie Girl
__________________
31mm Infiltrating duct carcinoma
Grade 3, ER/PR-, HER2+, Neg Sentinel nodes x 5
49mm field of DCIS
17 June '13: Screen detected impalpable mass, Mammogram neg, US.
25 June '13: Diagnosed after multiple biopsies and MRIs
28 June '13: Left lumpectomey
4 July '13: Left Mastectomy
12 August '13: Commenced TCH chemo
Mid December '13 : TCH finished. Herceptin continuing three weekly.
4 August 2014- Herceptin infusions finished.
END OF THERAPY - YAY!
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