I didn't have the nail problem while on Taxol, but did have it with taxotere (same family). My nails turned brown and were very soft and pulling away from the nail beds (all fingers and some toes). Once I stopped the drug, the nails grew back and are now normal (it's been a year of growth). Had I kept on taxotere, I would have lost all of my fingernails( yup, ANOTHER side effect).
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