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07-22-2010, 10:49 PM
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#1
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Senior Member
Join Date: May 2006
Location: California
Posts: 668
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Anyone with mets to chest wall
Hi,
What's the process when someone is dx with mets to the chest wall?.
My doctor's back-up called me two days ago and said that the Pet-Scan showed "suspicious" areas in the chest wall. The doc then did not allow me to ask much, --since he's only providing me with the results, and my doc will be back at the end of the month.
I'm not in pain, haven't been coughing much either, not swollen nor lumps in the chest area so far.
I'm just wondering if anyone else in the group has dealt with this.
What treatment did you do?
Is it possible to do a needle biopsy?
Symptoms?
Anyone? please respond.
Thank you
Adriana
__________________
1994 - rt brst, .lump, underarm node dissection,chemo+rad 1.2 cms, Grade 3.
28 nodes neg
Er,Pr, Positive HER2 status unknown
2003- Recur to rt lung.July 16 ( B-Day!)
Her2+++ Er,Pr, Negative
2003 - Aug04--Navelbine + Herceptin
2004- 2007--NED - Herceptin, only
2007 Feb-April Xeloda added to hereceptin
2007-May Back on Navelbine+Herceptin
2008-Feb-Mar 15 Ses Rad to Rt. Lung
2008- Oc 17 Add Tykerb to Herceptin
2009- June-- Discont Tykerb
2009 July 7--Current Taxol + Herceptin
2009 Dec--Discontinued treatment due to progression. Looking into cyberknife.
2010-Aug Accepted to TDM1, no SE, except liver count went up.
2010-2011 September got kicked out of the trial, due to a small spot found on lung.
2011- 2012 September thru early 2013 on Herceptin
2013- March Bone density shows small spot on 5th rib.
2013 - April 4th appt with onc. will post after discussing course of treatment.
2013-March-April Cyber knife to brain and radiation to rib. Chest --base line before chemo-CT-Scan stable for lung issue. CA2729 Normal.
2013 April Herceptin- TDMI
2013 Sept Herceptin + Perjeta . CA2729 within normal range. Brain and Pet scans October 31st. will post results.
2013 October Brain MRI- mixed response. Will see Onc/rad on Halloween.
2013 October/November Brain-MRI nothing new. Repeat MRI next year in May.
2013 December Continue Herceptin and Perjeta. Stable at the moment.
2014 February Brain MRI -clear!
2014 January Added Taxotere to Perjeta+Herceptin.
2014 March Stopped chemo-chest ct-scan next.
2014- March Scans shows tumor's larger, CA2729 higher. Discontinue Herceptin.
2014 April Perjeta+ Halaven
2014 April CA2729 went down 60 points after one cycle. Cough does not want to go away.
2014 June Continue on Perjeta + Halaven-- no more cough. Stable
2014 June Back on Herceptin + abraxane
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07-23-2010, 08:08 AM
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#2
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Senior Member
Join Date: Jul 2006
Location: Newfoundland, Canada
Posts: 153
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Re: Anyone with mets to chest wall
Adriana,
I ve had mets to the chest wall since Jan 2009. They havent' changed since they showed on the scan. I went on aromasin for a year and aredia infusions every 6 weeks. In Dec 2009 mets showed in my liver and am now on xeloda, aredia and herceptin. My last scan in june showed no change again in the chest wall and the liver has gone from 6 lesions to 5 and the 5th one which was the biggest has changed from 20mm to 5mm. My chest wall lesion could be healing as it hasn't changed for over a year. But until my liver mets I was doing fantastic on just aromasin.
Hope its the same for you.
Dawn
__________________
Dawn
Mar 2006Stage IIIA, Her2/Neu 3+++, Er & Pr positive, 8 of 18 pos 03/14/06: Mastectomy 04/19/06 started Chemo adriamycin, chlophosphamide, taxotere 25 rads
Nov 1, 06: 3 years Tamoxifen, Herceptin (1yr)
Jan 2009 Femara mets to bone aromasin and aredia
June2009: Full Histerectomy
2/22/2010 6 spots in liver 2 mm-10 mm: switched to xeloda and Herceptin will continue with Aredia J
Scan February 2011 new onc, switch to abraxane
April 2011 NED clear organs, 3 spots on bone scar tissue.
Scans August 2mm spot on liver and lungs. now on to tykerb/xeloda
Dec 2011 scans nothing on lungs, liver down to 1 2 mm spot. j
une 2012 another spot on liver on to cisplatin/gemzar.
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07-23-2010, 12:39 PM
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#3
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Senior Member
Join Date: Jul 2006
Posts: 869
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Re: Anyone with mets to chest wall
Adriana, So very sorry to hear this news--any update on the lung issue? Sorry I don't have any answers, here, but Happy Belated July 16th b-day, same as me! Ceesun
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07-24-2010, 01:48 AM
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#4
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Senior Member
Join Date: Feb 2006
Location: Southern, CA
Posts: 2,511
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Re: Anyone with mets to chest wall
Adriana, When I recurred back in Sept. 09 I was told matter of fact I recurred in rt femur, axilla and chest wall. After seeing my onc about this recurrence...I asked her how do they normally trt the chest wall...radiation? She said yes. (I can't have radiation to my chest due to lung issues.)
I was very concerned. I got a copy of my PET/CT as I always do and read it myself. Well...it mentioned chest wall but it said something that's off the midline to the right in chest wall. It turned out to be my seroma that has been there forever! I'm not sure why the rads tech wrote it up the way he did...but as they say...an x-ray, scan, etc is only as good as the guy that reads it. I've also had "suspicious" on reports and it turned out to be nothing. My liver was suspicious once on the PET portion...but CT did not collaborate this. Turn out to be nothing.
As far as doing a biopsy it mainly depends on the location in chest wall as I understand it? It could be a needle, wire or sometimes a surgical biopsy. Someone pls correct me if I'm wrong? I know one women at my cancer center that was dx with mets to chest wall 4 yrs ago...they have remained stable and she is only on Herceptin/Femara. I hope everything turns out ok for you.
Chelee
__________________
DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
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07-26-2010, 02:28 PM
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#5
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Senior Member
Join Date: Jul 2007
Location: Northern California
Posts: 764
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Re: Anyone with mets to chest wall
Adriana,
I just got dx with this. My onc said I needed a biopsy. I not sure how to treat it since I already have had so much radiation. Maybe we can share info.
Thanks, Tonya
__________________
DX 02/01/07
2.5 cm, Er/Pr-, Her2+++
18/20 Nodes
03/07 CT & Bone scan - Clear
AC x 4, Taxol x 4, Added Herceptin
Radiation until 09/07
Herceptin every 3 weeks until 06/08
01/10/08 local recurrence -IBC
01/28/08 CT & Brain MRI - clear
02/08 - Navelbine & Herceptin
05/08 -MRM
05/08 - Gemzar & Herceptin - didn't work
09/08 - Hyperthermia rads
03/09 - Tykerb/Xeloda
05/10 - Tram flap to fix wound
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07-30-2010, 02:16 PM
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#6
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Senior Member
Join Date: Oct 2007
Posts: 1,851
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Re: Anyone with mets to chest wall
Adriana,
Sorry to hear about this development. You're in my prayers.
Joan
__________________
Diagnosed stage 2b in July 2003 (2.3 cm, HER2+, ER-/PR-, 7+ nodes). Treated with mastectomy (with immediate DIEP flap reconstruction), AC + T/Herceptin (off label). Cancer advanced to lung in Jan. 2007 (1 cm nodule). Started Herceptin every 3 weeks. Lung wedge resection April 2007. Cancer recurred in lung April 2008. RFA of lung in August 2008. 2nd annual brain MRI in Oct. 2008 discovered 2.6 cm cystic tumor in left frontal lobe. Craniotomy Oct. 2008 (ER-/PR-/HER2-) followed by targeted radiation (IMRT). Coughing up blood Feb. 2009. Thoractomy July 2009 to cut out fungal ball of common soil fungus (aspergillus) that grew in the RFA cavity (most likely inhaled while gardening). No cancer, only fungus. Removal of tiny melanoma from upper left arm, plus sentinel lymph node biopsy in Feb. 2016. Guardant Health liquid biopsy in Feb. 2016 showed mutations in 4 subtypes of TP53. Repeat of Guardant Health biopsy in Jana. 2021 showed 3 TP53 mutations, BRCA1 mutation and CHEK2 mutation. Invitae genetic testing showed negative for all of these. Living with MBC since 2007. Stopped Herceptin Hylecta (injection) treatment in March 2020. Recent 2021 annual CT of chest, abdomen and pelvis and annual brain MRI showed NED. Praying for NED forever!!
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