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Old 06-05-2006, 02:28 PM   #1
StephN
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Join Date: Nov 2004
Location: Misty woods of WA State
Posts: 4,128
Exclamation HER2 vaccine blues - but wait ...

Well gang, I am once again disqualified from a vaccine trial due to something in my body chemistry. My ANA (antibodies to nuclear antigen) is still positive, so that must be the way I am. This means the DNA vaccine trial at the U of W is out for me.
Still have not seen my FISH number, but that may not matter any more.

There WAS one BRIGHT spot in a message from Patty at the U of W Tumor Group.
She says there is another vaccine that will begin a phase II study the end of summer. It is not specifically a HER2 target, but works against 5T4, something common to tumors of various origins.
Only thing is :
"This phase II trial is studying how well vaccine therapy works in treating patients with stage IIIB or stage IV breast cancer in remission."

Remission is required for this Trovax study and at this time I qualify. The trial criteria says that bone mets is the only qualifier, but Patty says that has been changed and the patient can have had mets anywhere and qualify. They are updating the wording.
If interested check this link:
http://www.clinicaltrials.gov/ct/show/NCT00227474?order=1
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