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Old 01-21-2011, 08:42 AM   #1
Jean
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Join Date: Oct 2005
Location: New Jersey
Posts: 3,154
minimal prognostic or survival rate value in analysing sentinel lymph node tissue for

http://www.medicalnewstoday.com/articles/214332.php
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Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
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Old 01-24-2011, 03:26 PM   #2
Becky
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Location: Stockton, NJ
Posts: 4,179
Re: minimal prognostic or survival rate value in analysing sentinel lymph node tissue

Dear Jean

Thanks for posting. As some may know, my initial sentinel node screening was "node negative" but later, upon further inspection, it was found I had 2 small micromets to the sentinel node and was deemed node positive. My tumor was 1.9 cm but in a sense (now) I am alittle grateful for that minor positive node because over 6 years ago, they would have only given me 4AC treatments and no taxol. I also believe that later, when Herceptin became available, I would have had trouble getting that too due to negative nodes (although the tumor size was formible). There were other issues too as Sloane Kettering's evaluation was that they felt the tumor might have been bigger and measurement was hampered by a large cyst (11cm) that was pressed tightly against the tumor (tumor was probably hampering proper lymph drainage).

So, its nice I had the book thrown at me at a time when one would have had to fight to get the book thrown at them if they were node negative (and that my micromets really don't mean much prognostically).
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Kind regards

Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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Old 02-01-2011, 01:06 PM   #3
AlaskaAngel
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Re: minimal prognostic or survival rate value in analysing sentinel lymph node tissue

Let's hope the era of indiscriminate treatment may be coming to an end soon...

http://her2support.org/vbulletin/sho...790#post243790
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Dx 2002 age 51
bc for granny, aunt, cousin, sister, mother.
ER+/PR+/HER2+++, grade 3
IDC 1.9 cm, some DCIS, Stage 1, Grade 3
Lumpectomy, CAFx6 (no blood boosters), IMRT rads, 1 3/4 yr tamoxifen
Rads necrosis
BRCA 1 & 2 negative
Trials: Early detection OVCA; 2004 low-dose testosterone for bc survivors
Diet: Primarily vegetarian organic; metformin (no diabetes), vitamin D3
Exercise: 7 days a week, 1 hr/day
No trastuzumab, no taxane, no AI
NED
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