Neratinib Clinical Trial

KristyAnn · 03-02-2010, 03:10 PM

I have heard that too- all I really understand is that Herceptin blocks Her2 and neratinib blocks other HER receptors. My onc mentioned that many times when they have a HER2+ person with a recurrence after herceptin, further testing shows there is also an abundance of other HER receptors (like Her3 and 4) and that neratinib may also block those.
Kristy

1rarebird · 03-03-2010, 06:41 AM

Thanks, Kristy--
I am glad to see that the chemo-brain didn't affect my memory that badly after all and that I wasn't imagining things regarding the cross-talk issue. I will keep looking in my files to find the actual paper on this.

I met with my oncologist again 2 days ago and he said that our treatment center is almost finished with the paper work to get approval so it can participate in this trial. He also mentioned that accrual is going well for the trial so far, but that due to the numbers (3500 or so) patients that are being recruited, he expected it to remain open for a couple more years. That should leave me ample time to get on on the trial after I am done with the Herceptin this July.

bird

freyja · 04-10-2010, 09:59 AM

Hey ladies and gentlemen,
Don't know if you remember but I was approved for this trial way back in January but my treatment center somehow were prevented from starting it for some technicality. Now they are back on board, and I should start in a couple weeks when we got all the scans and tests redone. I'll be here reporting on the progress.
Celeste