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Old 03-09-2011, 07:19 AM   #1
Barbara2
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Join Date: Sep 2005
Location: South Dakota.
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Results of Utility of Long-term Herceptin Use After Adjuvant Chemotherapy

http://www.cancernetwork.com/practic.../10165/1816904

Overall, the study shows that Herceptin is efficacious as an adjuvant treatment. Nevertheless, the result that extending the period between chemotherapy and the start of Herceptin to 1 to 3 years has a benefit for early breast cancer patients will need to be followed up with a controlled, randomized clinical trial. The optimal Herceptin duration of treatment is still not known and is the subject of ongoing clinical trials. Furthermore, as the author of the accompanying editorial mention, a 4-year follow up is still quite short for an adjuvant trial and it may still play out that concurrent chemotherapy and Herceptin treatment is a more effective strategy that chemotherapy followed by Herceptin in an adjuvant setting.
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Blessings and Peace,
Barbara

DX Oct 02 @ age 52 Stage 2B Grade 3 Mastectomy
"at least" 4.5 cm IDC 1+node ER+61% /PR-
Assiciated Intraductual component with Comedo Necrosis
Her2+ FISH8.6 IHC 2+
5 1/2 CEF Arimidex
Celebrex 400mg daily for 13 months
Prophylactic mastectomy
Estradiol #: 13
PTEN positive, "late" Herceptin (26 months after chemo)
Oct 05: Actonel for osteopenia from Arimidex.
May 08: Replaced Actonel with Zometa . Taking every 6
months.

Accepting the gift of life, I give thanks for it and live it in fullness.
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