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Old 02-19-2011, 01:34 PM   #1
TriciaK
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Chemo list ?

I think there is a list somewhere of different chemos---if so would like to study them. I have not had a lot of experience with chemos, especially considering I have been fighting breast cancer for 25 years---first in rt. breast (1985), then spine (1990), then her2 in rt. lung (2004) and now again same place. I only had chemo (navelbine) with herceptin in 2004, which worked very well with no side effects. Now this time, navelbine had weird side effects, so had to stop it. The first gemzar had no side effects but second had really bad rash, though it lowered the ca27-29. As I posted here earlier, my oncologist is trying to decide what to try next, maybe even Gemzar again with allergy meds. I really appreciated the suggestions I received. If you know of a list of chemos I would appreciate being able to do some more research. It is a little urgent because the MRI shows the nodule is growing. Thank you all for help, suggestions, and good thoughts. Hugs, TriciaK
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Old 02-19-2011, 03:22 PM   #2
sassy
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Re: Chemo list ?

Tricia,

http://her2support.org/her2-breast-cancer/chemo-drugs

This is a link to our chemo drug list. It has not been updated since this time last year, so there may be a few new ones not listed. This may not have as much in depth info as you would like, but may give you a start. If I can help you find additional drugs or more detailed info about a drug, please PM me and I will see what I can do.
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Old 02-19-2011, 05:43 PM   #3
tricia keegan
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Re: Chemo list ?

I don't have advice Tricia but hoping your onc finds something to zap this fast for you, sending my good wishes and regards !!x
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Dx July '05 IDC 1.9cm Triple positive 3/9 nodes positive
A/C X 4 ..Taxol/Herceptin x 12 wks then herceptin 1 yr
Rads x 36 ..oophorectomy August '06
Currently taking Arimidex..
June 2011 osteopenia/ zometa x1 yearly- stopped Zometa 2015 as Dexa show normal bone density.
Stopped Arimidex July 2014- Restarted Arimidex 2015 for a further two years on the advice of my Onc.
2014 Normal Dexa scan
2018 Mammo all clear, still NED!
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Old 02-19-2011, 06:51 PM   #4
Joan M
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Re: Chemo list ?

Tricia,

Eribulin (halaven) is a drug approved by the FDA in November for advanced breast cancer. Perhaps this could be an option.

Here's a news article about the drug:

http://www.medicalnewstoday.com/articles/208238.php

Hugs,

Joan
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Diagnosed stage 2b in July 2003 (2.3 cm, HER2+, ER-/PR-, 7+ nodes). Treated with mastectomy (with immediate DIEP flap reconstruction), AC + T/Herceptin (off label). Cancer advanced to lung in Jan. 2007 (1 cm nodule). Started Herceptin every 3 weeks. Lung wedge resection April 2007. Cancer recurred in lung April 2008. RFA of lung in August 2008. 2nd annual brain MRI in Oct. 2008 discovered 2.6 cm cystic tumor in left frontal lobe. Craniotomy Oct. 2008 (ER-/PR-/HER2-) followed by targeted radiation (IMRT). Coughing up blood Feb. 2009. Thoractomy July 2009 to cut out fungal ball of common soil fungus (aspergillus) that grew in the RFA cavity. No cancer, only fungus. Still continuing on only Herceptin. Removal of tiny melanoma from upper left arm, plus sentinel lymph node biopsy in Feb. 2016. Guardant Health liquid biopsy in Feb. 2016 showed mutations in 4 subtypes of TP53. Living with MBC for 11 years. Praying for NED forever!!
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Old 02-19-2011, 09:07 PM   #5
ElaineM
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Wink Re: Chemo list ?

I don't have a chemo list, but I am wondering if you and your doctor can negotiate about the dose or taking the drug with a different schedule. Sometimes a doctor will reduce the dose a little or give the drug every other week instead of every week if the drug appears to be working, but the patient is having alot of side effects.
There may also be other chemos you haven't tried yet.
There are alot of new drugs being tested that will be available in the not so distant future. Several of our members have tried T DM1 or are trying Halaven. You might ask them to share their experiences with you.
Have you tried Abraxane? It is Taxol with a less dangerous binder.
It is good to do research about our health problems and what kinds of treatments are available to us, so we can participate in our health care.
Take good care of yourself.
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Old 02-20-2011, 10:46 AM   #6
ElaineM
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Wink Re: Chemo list ?

Here is another list.

http://www.breastcancer.org/treatmen.../medicines.jsp
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ElaineM
12 years and counting
http://her2support.org/vbulletin/showthread.php?t=48247
Lucky 13 !! I hope so !!!!!!
http://her2support.org/vbulletin/showthread.php?t=52807
14 Year Survivor
http://her2support.org/vbulletin/showthread.php?t=57053
"You never know how strong you are until being strong is the only choice you have." author unknown
Shared by a multiple myeloma survivor.
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Old 02-20-2011, 01:34 PM   #7
Jackie07
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Re: Chemo list ?

Crit Rev Oncol Hematol. 2011 Feb 15. [Epub ahead of print]
Treatment of metastatic breast cancer: State-of-the-art, subtypes and perspectives.

El Saghir NS, Tfayli A, Hatoum HA, Dinh P, Awada A.
Breast Center of Excellence, NK Basile Cancer Institute, American University of Beirut Medical Center, PO Box 11-0236, Riad El-Solh 1107 2020, Beirut, Lebanon.
Abstract

Current treatment of metastatic breast cancer (MBC) aims at achieving meaningful clinical responses, improved quality of life, long-term remissions, prolonged survival, and dares to hope for a cure in a small percentage of cases. This article will discuss both consensus and controversies in the management of MBC in the context of the new evolving breast cancer molecular classification.

Hormonal therapy remains the mainstay of management of MBC Luminal A and B. Data is emerging on management of ErbB2-positive HR-positive MBC by combining hormonal manipulation and targeted anti-ErbB2 therapy and has recently received regulatory approval in Europe and USA. The optimal use and duration of single agent or combination chemotherapy is discussed. Data and controversies surrounding the use of newer agents such as nab-paclitaxel, ixabepilone, eribulin, and PARP inhibitors as well as trastuzumab is reviewed. Better understanding of pathophysiology has paved the way for the introduction of newer anti-ErbB2 agents such as lapatinib, pertuzumab, T-DM1 and neratinib. Controversies regarding bevacizumab and anti-angiogenesis are discussed. Bisphosphonates have significantly reduced skeletal related events and made significant improvements in the quality of life of patients with MBC. Newer anti-RANK Ligand antibodies show promising results.

Significant advances in the understanding of molecular biology of breast cancer have been made and should lead to an improvement in the outcome of MBC. More possibilities of cure can become an attainable goal in the near future.

[ErbB2 = Her2]
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Last edited by Jackie07; 02-20-2011 at 04:13 PM..
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Old 02-20-2011, 02:58 PM   #8
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Re: Chemo list ?

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More possibilities of cure can become an attainable goal in the near future.
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