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Need some help...
I've been going through a rough time due to a problem I've ran into with my lungs. I have compromised lung function to begin with. Not long ago my onc made an error with Navelbine/Herceptin and it really set me back. I've been on oxygen for 3 months now. I'm now able to function mostly without it unless I have to walk too far. This has excluded me from the T-DM1 trial since I'm on oxygen. 
My last PET/CT shows progression/uptake in both hips and pelvis. I need to start chemo. CA27.29 still going up...I have to get started which worries me since my lungs aren't fully recovered. I have been holding off chemo for too long but have to do something now. Currently I'm only on Herceptin/Zometa/Femara. Any idea's/thoughts on which chemo I could try at a lower dose that might not be so harsh on my lungs...yet still stop the progression with bone mets?
Chelee
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DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
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