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Old 04-13-2007, 11:32 AM   #1
RobinP
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colonscopy with breast cancer history?

I was just wondering if others have done a colonscopy due to cancer history even when you are younger? Thanks, my MD recommended this as an option for cancer screening even though no one in my immediate family has had colon cancer.
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2002- dx her2 positive DCIS/bc TX Mast, herceptin chemo
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Old 04-13-2007, 11:49 AM   #2
saleboat
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I wondered if I would have to do this, but so far, it hasn't been recommended. Maybe when I turn 40?
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dx 4/05 @ 34 y.o.
Stage IIIC, ER+ (90%)/PR+ (95%)/HER2+ (IHC 3+)
lumpectomy-- 2.5 cm 15+/37 nodes
(IVF in between surgery and chemo)
tx dd A/C, followed by dd Taxol & Herceptin
30 rads (or was it 35?)
Finished Herceptin on 7/24/06
Tamox
livingcured.blogspot.com

"Keep your face to the sunshine and you cannot see the shadow." -- Helen Keller
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Old 04-13-2007, 12:24 PM   #3
Becky
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I was and did so in April, 2006. It was recommended a year earlier but I procrastinated but I was clean (no pun intended)
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Kind regards

Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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Old 04-13-2007, 12:31 PM   #4
RobinP
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Hi Becky, I'm glad you were clean. How was the procedure? Was it as uncomfortable as it sounds, and do you know if there are any potentially adverse side effects, common or rare, such colon tearing or perforation? Thanks for the help...smile.
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Old 04-13-2007, 12:48 PM   #5
Hopeful
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I have been reccomended to have this test just because of my age (53). Would have done so last year, but bc kind of pushed it off the stage. I expect to get to it this summer. My local imaging place does virtual colonoscopy, which has the value of not requiring anesthesia, as it is non-invasive. I asked my gyn (who is ordering the test) if that would be ok with her, and she said sure. I will have to pay for it myself, but would prefer this to the standard procedure, so I don't mind.

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Old 04-13-2007, 12:52 PM   #6
Grace
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I had one recently and it was relatively easy; hardest part is drinking the liquid the night before. And today you can take a pill and drink water. All invasive procedures can have problems, but it's rare. My husband had two very miserable days after his, done in New York, because of the anesthesia. He had one in Italy (no anesthesia) and had no after effects. I don't think I'd consider doing it if not knocked out, but it is safer. If you have no polpys,you can usually wait another five years for the next; and if you have benign polyps then you are told to return in two years.
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Old 04-13-2007, 01:09 PM   #7
Yorkiegirl
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It was recommended that I have one , and I am glad that I did. They found 6 polyps but they turned out to benign.

Drinking the liquid stuff was yucky but tolerable. I was put under a local to have mine done and had no problems.

Since I had 6 polyps it now recommened that I have this once a year.
Unfortunately colon cancer and BC can go hand in hand, and thought well isn't that just great.
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Texas
Biopsy Dx'd 3-23-05 Age 48
MRM 4-5-05 w/ 2 tumor's 5cm, and 6 cm (right side)
IDC (poorly differentiated infiltrating ductual carcinoma)
5+/16 nodes
Stage III A
Grade 3
ER/PR-, Her2/neu ++
Ki67 78%
Begin Chemo 5-2-05 4XAC Dose Dense , 4X Abraxane Dose Dense (ended August 05)
28 Rad's ended October 13 2005
Started Herceptin Weekly August 2005 for one year
Had a Simple mastectomy left side after Mamo showed incresed micro-calcifications. Jan. 17 2006.
Brain MRI Feb.2006--All Clear
August 28, 2006 Last Weekly Herceptin.
October 2006--Colonoscopy, 6 Polyp's removed--all B9
PET Scan July 2007
Abdominal MRI Oct. 2007---2 Right Kidney Cysts
Core Biopsy-- Lump on Scar Line 1-10-08---B9
Brain MRI 6-2008--All Clear
PET/CT Scan 6-2008
Sept. 8 2008, 4CM area removed from mastectomy scar line. Proved to be B9.
PET/CT Scan-- July 2009 --All clear
August 17,2009 ---Had Port Removed
6 Years NED -- April 5,2011
DX'd with Melanoma left arm 10-10-2011
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Old 04-13-2007, 05:27 PM   #8
skeetur
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I had one last year (pre-cancer dx) at age 45 for some abdominal pain I was having.

My sister dxed with breast cancer last year as well has her first colonoscopy in a few weeks - it was suggested because of her age rather than the BC as she just turned 50.

Kathy
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12/01/2006 Initial Dx via stereotactic biopsy - DCIS, grade 3
12/27/2006 Lumpectomy w/ SNB: 2 foci of IDC (largest .3 cm, Grade 2, Notthingham score 6) amid large area of DCIS: No clear margins on the DCIS; re-excision recommended
ER+(55%)/PR+(60+)/HER2+ (2.8+ via IHC?)
01/23/2007 Re-excision Lumpectomy: No clear margins on the DCIS; mastectomy recommended
03/02/2007 Bilateral mastectomy w/ expander implant insertion
03/19/2007 Emergency surgery to fix broken blood vessel in left breast
03/30/2007 Met w/ oncologist; oncologist checking on HER2 status with pathologist and doing some consulting on my case - no treatments for now!
05/02/2007 Next appointment w/ oncologist
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Old 04-13-2007, 05:38 PM   #9
Becky
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The procedure was fine. I had a twilight anesthesia and was out and up in a flash. The drinking one gallon of trilyte was NO picnic. When I have to get another one in 4 years, I am getting the pills.
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Kind regards

Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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Old 04-13-2007, 08:23 PM   #10
hutchibk
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My doc has said that I can and probably should... but while on certain chemos that knock down my WBC, he has asked me to do it only at a certain point in the 3 week chemo cycle. I have asked him if we would see any other types of cancer (colon or ovarian) on any of my multitude of regular scans and he said
we would see ovarian, but not colon polyps.... so he would like me to follow thru on that. I, too, have been a procrastinator, but I intend to.
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Brenda

NOV 2012 - 9 yr anniversary
JULY 2012 - 7 yr anniversary stage IV (of 50...)

Nov'03~ dX stage 2B
Dec'03~
Rt side mastectomy, Her2+, ER/PR+, 10 nodes out, one node positive
Jan'04~
Taxotere/Adria/Cytoxan x 6, NED, no Rads, Tamox. 1 year, Arimadex 3 mo., NED 14 mo.
Sept'05~
micro mets lungs/chest nodes/underarm node, Switched to Aromasin, T/C/H x 7, NED 6 months - Herceptin only
Aug'06~
micro mets chest nodes, & bone spot @ C3 neck, Added Taxol to Herceptin
Feb'07~ Genetic testing, BRCA 1&2 neg

Apr'07~
MRI - two 9mm brain mets & 5 punctates, new left chest met, & small increase of bone spot C3 neck, Stopped Aromasin
May'07~
Started Tykerb/Xeloda, no WBR for now
June'07~
MRI - stable brain mets, no new mets, 9mm spots less enhanced, CA15.3 down 45.5 to 9.3 in 10 wks, Ty/Xel working magic!
Aug'07~
MRI - brain mets shrunk half, NO NEW BRAIN METS!!, TMs stable @ 9.2
Oct'07~
PET/CT & MRI show NED
Apr'08~
scans still show NED in the head, small bone spot on right iliac crest (rear pelvic bone)
Sept'08~
MRI shows activity in brain mets, completed 5 fractions/5 consecutive days of IMRT to zap the pesky buggers
Oct'08~
dropped Xeloda, switched to tri-weekly Herceptin in combo with Tykerb, extend to tri-monthly Zometa infusion
Dec'08~
Brain MRI- 4 spots reduced to punctate size, large spot shrunk by 3mm, CT of torso clear/pelvis spot stable
June'09~
new 3-4mm left cerrebellar spot zapped with IMRT targeted rads
Sept'09~
new 6mm & 1 cm spots in pituitary/optic chiasm area. Rx= 25 days of 3D conformal fractionated targeted IMRT to the tumors.
Oct'09~
25 days of low dose 3D conformal fractionated targeted IMRT to the bone mets spot on rt. iliac crest that have been watching for 2 years. Added daily Aromasin back into treatment regimen.
Apr'10~ Brain MRI clear! But, see new small spot on adrenal gland. Change from Aromasin back to Tamoxifen.
June'10~ Tumor markers (CA15.3) dropped from 37 to 23 after one month on Tamoxifen. Continue to monitor adrenal gland spot. Remain on Tykerb/Herceptin/Tamoxifen.
Nov'10~ Radiate positive mediastinal node that was pressing on recurrent laryngeal nerve, causing paralyzed larynx and a funny voice.
Jan'11~ MRI shows possible activity or perhaps just scar tissue/necrotic increase on 3 previously treated brain spots and a pituitary spot. 5 days of IMRT on 4 spots.
Feb'11~ Enrolled in T-DM1 EAP in Denver, first treatment March 25, 2011.
Mar'11~ Finally started T-DM1 EAP in Denver at Rocky Mountain Cancer Center/Rose on Mar. 25... hallelujah.

"I would rather be anecdotally alive than statistically dead."
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Old 04-13-2007, 10:18 PM   #11
Dinogirl
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Smile

Robin,

Hello, I cannot speak about having it younger than 50, however, my paternal grandmother had colon cancer, in addition to my maternal great aunt. I had a colonoscopy 4 years ago at age 49, and (the chicken that I am-translated.. I do not like unecessary pain) strongly requested (actually demanded-because my gastroenterologist said I didn't need an anesthesiologist, and that insurance probably wouldn't pay, but ins paid) to have an anesthesiologist to be with my airway (asthma), and so I could have the maximum sedation that was safe. I had no problems with the anesthesia-most are very short acting anyway. For those medically oriented, I believe what I had was Versed, Propofol, and Fentanyl as that is what the anesthesiologist said he would give me after we discussed my desires. It does help to speak up, that is the only way we will get what we want, and helps us feel some control over our lives.
Sorry to ramble on, but hope my point of view is helpful
Dinogirl
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Dinogirl

Diagnosed at age 52-March 2006
Lumpectomy for 0.6 cm IDC rt breast, Sentinel nodes neg (3) HER 2 FISH +, ER/PR +, Grade 2
Taxotere, Cytoxan - one cycle
Taxotere, Cytoxan, Herceptin - 3 cycles (every 3 wks)
Tolerated chemo well with help of Aloxi, Neulasta, Decadron, Benadryl, Immodium, Darvocet (this info provided for those who may be reluctant to have chemo)
35 Rads
Herceptin for one year through May 2007
Femara since 9/2/06
BRAC 1 and 2 neg
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Old 04-14-2007, 07:52 AM   #12
Sandy H
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I had one because of being over 50 and was out the whole time. The prep was no problem for me as I started drinking in the morning and was scheduled at 4:00 p.m. and home by 5:30. Went to a meeting at 6:30 after the procedure! So had a good night's sleep and spend most of the day in the bathroom-then the procedure. I think my primary physican may have requested an afternoon appointment so I wouldn't be up all night. You need to make sure you drink the necessary fluids the day before so you do not get dehydrated which happened to one of my friends. She was very ill from dehydration. I would not be nervous to do it again however, I was told 10 years as nothing was found. hugs, Sandy
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Dx. 03/01, Rt. IBC
AC/Taxatere
Rt. MRM-with graft Lt. simple
5 rads-skin mets
Herceptin, taxol, carboplatin (taxol seem to be the magic drug)
Navelbine & xeloda (did not work)
topical miltex for skin mets
Tykerb/xeloda
thoracentesis x 2 left lung fluid shows cancer cells
Port removal (4 years) with power port replacement
Doxil
Updated 05-07 Scans show no bone or organ involvement we shall see!




I shall not pass this way again. Any good I can do or any kindness that I can show let me not defer or neglect it for I shall not pass this way again.
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Old 04-23-2007, 12:10 PM   #13
Lani
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virtual colonoscopy as an alternative

CT Colonography May be Most Cost-Effective for Colon Cancer Screening

Laurie Barclay, MD

April 23, 2007 — Computed tomography colonography (CTC) with nonreporting of diminutive lesions, which have a low malignancy rate, was more cost-effective than optical colonoscopy for colon cancer screening, according to the results of a study published online in the April 23 Early View of the June 1 print issue of Cancer.

"Prior cost-effectiveness models analyzing...CTC screening have assumed that patients with diminutive lesions (?5 mm) will be referred to optical colonoscopy (OC) for polypectomy," write Perry J. Pickhardt, MD, from the University of Wisconsin, in Madison, and colleagues. "However, consensus guidelines for CTC recommend reporting only polyps measuring ?6 mm. The purpose of the current study was to assess the potential harms, benefits, and cost-effectiveness of CTC screening without the reporting of diminutive lesions compared with other screening strategies."

Despite the availability of effective screening tests for colon cancer, screening rates remain low and deaths remain high; colorectal cancer is the third leading cause of cancer death in both men and women. OC and flexible sigmoidscopy, which have been the primary screening tools for the past few decades, can give rise to complications ranging from abdominal pain to bowel perforation and bleeding.

CTC, also known as virtual colonoscopy, uses x-rays and imaging software to create 2- and 3-dimensional images of the gastrointestinal tract, with higher tolerability and fewer adverse effects than OC and flexible sigmoidscopy.

Using a Markov model applied to a hypothetical cohort of 100,000 people aged 50 years, the investigators determined the cost-effectiveness of screening with CTC (with and without a 6-mm reporting threshold), OC, and flexible sigmoidoscopy.

Compared with no screening, the model predicted an overall cost per life-year gained of $4361, $7138, $7407, and $9180, respectively, for CTC with a 6-mm reporting threshold, CTC with no threshold, flexible sigmoidscopy, and OC. Although the additional costs associated with the reporting of diminutive lesions at the time of CTC amounted to $118,440 per additional life-year gained, the incidence of colorectal cancer was reduced by only 1.3% (from 36.5% to 37.8%).

CTC with a 6-mm threshold yielded a 77.6% reduction in invasive endoscopic procedures (39,374 vs. 175,911) and 1112 fewer reported OC-related complications from perforation or bleeding than with primary OC screening.

"CTC with nonreporting of diminutive lesions was found to be the most cost-effective and safest screening option evaluated, thereby providing further support for this approach," the authors write. "Overall, the removal of diminutive lesions appears to carry an unjustified burden of costs and complications relative to the minimal gain in clinical efficacy."

Study limitations include failure to consider the need for recovery time after OC, the need for a second person to drive the patient home after OC, pathology costs related to the histologic evaluation of polyps, and costs of additional workups related to extracolonic abnormalities detected with CTC.

"These results provide further support for the practice of a 6-mm polyp size reporting threshold at CTC screening," the authors conclude. "The use of primary CTC screening as a selective filter for OC polypectomy for lesions measuring ?6 mm represents a potentially powerful new approach to CRC screening."

Cancer. Published online April 23, 2007.
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Old 04-24-2007, 11:50 AM   #14
RobinP
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Thanks, everybody, I'm going to copy your posts for encouragement to do the procedure.
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2002- dx her2 positive DCIS/bc TX Mast, herceptin chemo
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