Re: getting her2+ER- bc to reexpress ER & consequences more complicated than thought
Has there been any studies for fulvestrant or exemestane (Aromasin) vs the non-steroidal AI's for non-metastatic HER2 breast cancer?
I"m also not clear on where fulvestrant fits into the picure vs tamoxifen, aromasin/femara, and aromasin, particularly with non-metastatic cancer. I think it was developed as a treatment for metastatic cancer, but is now branching into locally advanced cancer, etc?
Thanks
TRS
__________________
Terri, spouse of Ruth, Dallas/Ft. Worth area
Ruth dx 05/01/07 (age 50) Filipino
multifocal, several tumors .5 -2.5 cm, large area
Breast MRI showed 2 enlarged nodes, not palpable
100%ER+, 95%PR+, HER2+++
6x pre-surgery TCH chemo finished 9/15/7 Dramatic tumor shrinkage
1 year Herceptin till 6/08
MRM 10/11/07, SNB: 0/4 nodes + Path: tumors reduced to only a few "scattered cells"
now 50% ER+, PR- ???
Rads finished 1/16/08
Added Tamoxifen,
Finished Herceptin 05/08
NOW is the time to appreciate life to the fullest.
Last edited by TSund; 01-05-2010 at 09:32 AM..
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