Metabolic management of cancer

[AlaskaAngel]

On 2/2/07, eric posted a question about DCA (dicholoroacetate) that was interesting. Following that thread, meredith posted another on 3/9/07, and then Christinemhk posted another on 10/4/07.

I too have been interested in the possible metabolic management of cancer, and have initiated threads about recent information regarding the use of metformin for its effects on the mitochondria.

Because of the further posts by Rich that included more info about DCA and other possible clues regarding cancer and metabolic management, I thought I would post this update on DCA that I found. I don't have the current status of DCA, but for those who wonder if the DCA idea "died" as being "too far out" and "too kooky" in comparison to the standard treatment with chemotherapies, or whether the research into DCA has continued to slowly make progress, this is something of an update on DCA.

This research over time into DCA also provides some insight into the controversies about obstruction in the development of better treatments, and whether the system we have for recommending treatments now is self-perpetuating in favoring more toxic treatments, due in part to our desperation at time of diagnosis and our tendency to want to rely on treatments that hit cancer "as hard as possible".

http://scienceblogs.com/insolence/20...oroacetate.php

Because the discussions in those earlier threads were also interesting, here are some of them over time:

http://her2support.org/vbulletin/sho...&highlight=DCA

http://her2support.org/vbulletin/sho...&highlight=DCA

http://her2support.org/vbulletin/sho...&highlight=DCA

http://her2support.org/vbulletin/sho...&highlight=DCA

One way to make better progress with such work as the metabolic management of cancer would be to train endocrinologists to focus specifically on metabolic management of cancer and to sit as members with full authority to make recommendations for treatment on each of our tumor boards. It could provide more humane and less expensive solutions for the generations to come.

AlaskaAngel