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Old 03-18-2005, 03:39 PM   #1
al from canada
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Hi Michele,
The reason I asked if you have mets is because generally, once there are mets, you are officially stage 4, and mastectomies are no longer considered as the cancer is now systemic. I do question why are you are considering a prophylactic bilateral mastectomy. Have you tested positive for the BRCA1 or BRCA2 genes? If you haven't, my reservation would be the activation of HER2 from the surgical trauma of the mastectomies. There seems to be a fair amount of evidence that HER2 can be activated in this way and result in cancer spread. I know some on the board would disagree with me but.....
Good luck in your decision.
Al
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